Early And Late Symptoms Of Parkinsons Disease
Parkinsons disease is a common neurodegenerative disorder. It is characterized by progressive loss of muscle control, stiffness, slowness, and impaired balance. As the disease progresses the patient presents symptoms such as difficulty in walking, talking, and completing simple tasks.
The adult onset of disease is very common and it is mostly seen in the people aged 60 years or elder. Early onset i.e. age between 21-40 years or juvenile onset i.e. below 21 years of age can also occur.
What’s The Difference Between Memory Loss And Parkinson’s Dementia
Alzheimer’s dementia and Parkinson’s disease can both affect a person’s memory, but not in the same way.
Generally speaking, Parkinson’s dementia is not associated with the sort of memory loss that comes with Alzheimer’s, the most common form of dementia. Put differently: It doesn’t typically impact a person’s ability to absorb and store new memories or information the way Alzheimer’s does.;
“You can learn , but it’s difficult to retrieve the information that you have in your brain,”Irene Litvan, MD, director of the Movement Disorder Center at the University of California, San Diego, tells Health. “You may not know where the cassette is, but if somebody asks you, ‘Where were you when you lost it?’ You can say, ‘Oh, I was there.'”;
But that’s not to say Parkinson’s disease dementia doesn’t affect memory at all. On the contrary, some people with Parkinson’s dementia do indeed experience short- and long-term memory loss. They might also forget how to perform simple tasks, like how to run the dishwasher. And since Parkinson’s can affect people in different ways, there’s no way to tell whether someone with the disease will experience memory loss related to dementia.
Do What You Can While You Can
I have had Parkinsons disease for nearly 20 years. My wife is a teacher, so we travel every summer when she is not working. Since my diagnosis, I have been to China, Nepal, Prague, Paris and many other places. The Parkinsons comes along, too, so our trips require more planning than they used to and we involve my care team. We factor in daily naps and take it slow. My balance isnt as good as it used to be and too much walking wears me out so we bring a collapsible wheelchair along or make sure one is available. I also use a cane. I dont know how many more places we will get to visit as my disease continues to progress, but we have made some wonderful memories that we wouldnt have if we had let my Parkinsons dictate every aspect of our lives. Nicholas, diagnosed at 52, still traveling at 72
Many people with Parkinsons disease are not allowing the condition to take over their lives. Despite the everyday setbacks they face, they are still creating fulfilling lives for themselves by redirecting their attention to people and activities that bring them joy. You can do the same. Try building a few hobbies into your routine that will give you a break from dwelling on the disease. Find some activities that help you forget about Parkinsons for a while. That may be painting, writing, gardening, or reading to your grandchildren. ;
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Tips For Caring For Someone With Parkinsons Disease
Caring for a loved one with early onset Parkinsons can be difficult. If youre a caregiver for someone with this condition, its important that you remember your own emotional and physical health.
Not only are you dealing with a difficult diagnosis, youre also managing an increased number of responsibilities. Burnout is common in caregivers, so make sure youre checking in with your own needs.
The Michael J. Fox Foundation Center for Parkinsons Research recommends these tips for caregivers:
What Are The Different Stages Of Parkinsons Disease
Each person with Parkinsons disease experiences symptoms in in their own unique way. Not everyone experiences all symptoms of Parkinsons disease. You may not experience symptoms in the same order as others. Some people may have mild symptoms; others may have intense symptoms. How quickly symptoms worsen also varies from individual to individual and is difficult to impossible to predict at the outset.
In general, the disease progresses from early stage to mid-stage to mid-late-stage to advanced stage. This is what typically occurs during each of these stages:
Early symptoms of Parkinsons disease are usually mild and typically occur slowly and do not interfere with daily activities. Sometimes early symptoms are not easy to detect or you may think early symptoms are simply normal signs of aging. You may have fatigue or a general sense of uneasiness. You may feel a slight tremor or have difficulty standing.
Brief Description Of Treatment
You didnt want to need any treatment in the early stages of Parkinsons disease because the symptoms are usually mild. However, you are to visiting your specialist regularly so that your condition can be monitor.
Currently, there is no treatment for Parkinsons disease. However, there are a number of treatments available to control symptoms and maintain your quality of life. These may be supportive therapy to help you cope with daily life or medicines to control your symptoms. For individuals with certain symptoms, surgery may be an option.
You are agree on a care plan with your health care workers and your family or caregiver, and it should be review regularly.
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Stooping Or Hunched Posture
People who have Parkinsons disease may notice changes in their posture due to other symptoms of the disease, such as muscle rigidity.
People naturally stand so that their weight is evenly distributed over their feet. However, people who have Parkinsons disease may start bending forward, making them appear hunched or stooped over.
Braaks Hypothesis On How Parkinsons Disease Begins
Braaks hypothesis, named for professor Heiko Braak, MD, who outlined the theory in 2003, suggests that rather than beginning in the brain, Parkinsons disease begins in the periphery of the body. Braaks hypothesis proposes that the earliest signs of PD are found in the gut and the olfactory bulb, an area of the brain involved in the sense of smell.2-4
The accumulation of the protein alpha-synuclein is believed to begin in the gastrointestinal tract or the olfactory bulb before progressing to other areas of the brain. After the aggregates of alpha-synuclein have formed, they appear to be capable of growing and spreading from nerve cell to nerve cell across the brain.2-4
The appearance of alpha-synuclein aggregates coincides with the appearance of symptoms: alpha-synuclein aggregates in the brainstem correlates with the onset of motor symptoms. Appearance of alpha-synuclein aggregates in the cortex correlates with dementia and cognitive dysfunction.2-4
Is There A Way To Slow The Progress Of Parkinsons
Parkinsons disease is a progressive disorder, which means its symptoms worsen slowly over time. There is no cure for Parkinsons disease yet and no known way to slow its progress.
But there are treatments and medications that can control or reduce the symptoms and help people live productive lives. Some research suggests that regular exercise may slow the progress of Parkinsons. Physical activity can also alleviate stiffness and other symptoms.
Early symptoms of Parkinsons
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What Is The Treatment For Parkinson’s Disease
There is currently no treatment to cure Parkinson’s disease. Several therapies are available to delay the onset of motor symptoms and to ameliorate motor symptoms. All of these therapies are designed to increase the amount of dopamine in the brain either by replacing dopamine, mimicking dopamine, or prolonging the effect of dopamine by inhibiting its breakdown. Studies have shown that early therapy in the non-motor stage can delay the onset of motor symptoms, thereby extending quality of life.
The most effective therapy for Parkinson’s disease is levodopa , which is converted to dopamine in the brain. However, because long-term treatment with levodopa can lead to unpleasant side effects , its use is often delayed until motor impairment is more severe. Levodopa is frequently prescribed together with carbidopa , which prevents levodopa from being broken down before it reaches the brain. Co-treatment with carbidopa allows for a lower levodopa dose, thereby reducing side effects.
In earlier stages of Parkinson’s disease, substances that mimic the action of dopamine , and substances that reduce the breakdown of dopamine inhibitors) can be very efficacious in relieving motor symptoms. Unpleasant side effects of these preparations are quite common, including swelling caused by fluid accumulation in body tissues, drowsiness, constipation, dizziness, hallucinations, and nausea.
The Most Important Thing
The diagnosis of Parkinsons disease is often delayed.
Unfortunately, people often neglect the early symptoms. It is not unusual for 5 years to go by before the patient is finally diagnosed with Parkinsons disease.
In addition to symptoms, a doctors examination may uncover additional early signs of Parkinsons disease.
Do not neglect these symptoms. Talk to your doctor early.
|Caution: This information is not a substitute for professional care. Do not change your medications/treatment without your doctor’s permission.|
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Stiffness And Slowed Movements
Watch for an abnormal stiffness in your joints along with muscle weakness that doesnt go away and makes everyday tasks like walking, teeth brushing, buttoning shirts, or cutting food difficult. If you no longer swing your arms when walking, your feet feel stuck to the floor , or people comment that you look stiff when you havent been injured, the National Parkinson Foundation suggests seeing a doctor.
Learn more about these types of leg pain.
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Mood And Mental Problems
- Deal with depression. If you are feeling sad or depressed, ask a friend or family member for help. If these feelings don’t go away, or if they get worse, talk to your doctor. He or she may be able to suggest someone for you to talk to. Or your doctor may give you medicine that will help.
- Deal with dementia. Dementia is common late in Parkinson’s disease. Symptoms may include confusion and memory loss. If you notice that you are confused a lot or have trouble thinking clearly, talk to your doctor. There are medicines that can help dementia in people with Parkinson’s disease.
What Is Rem Behavior Disorder And How Is It Connected To Parkinson’s
A: REM behavior disorder is different than other sleep problems, like insomnia. People who have it may jerk or kick it’s as though they are acting out their dreams. In a similar pattern to anosmia, people with idiopathic REM sleep behavior disorder have at least a 50 percent chance of eventually developing Parkinson’s disease.
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Speech And Language Therapy
Up to half of the people with Parkinsons disease have communication problems, such as slurred speech or poor body language. If you have communication problems, a speech and language therapist can help you improve your speech and language use. They may use verbal exercises and tools to help you express yourself clearly.
Depression May Be An Early Symptom Of Parkinsons
Depression is one of the most common, and most disabling, non-motor symptoms of Parkinsons disease. As many as 50 per cent of people with Parkinsons experience the symptoms of clinical depression at some stage of the disease. Some people experience depression up to a decade or more before experiencing any motor symptoms of Parkinsons.
Clinical depression and anxiety are underdiagnosed symptoms of Parkinsons. Researchers believe that depression and anxiety in Parkinsons disease may be due to chemical and physical changes in the area of the brain that affect mood as well as movement. These changes are caused by the disease itself.
Here are some suggestions to help identify depression in Parkinsons:
- Mention changes in mood to your physician if they do not ask you about these conditions.
- Complete our;Geriatric Depression Scale-15;to record your feelings so you can discuss symptoms with your doctor. Download the answer key and compare your responses.
- delusions and impulse control disorders
Early Symptoms Of Parkinsons Can Be Overlooked
Symptoms of Parkinsons disease are divided into 2 groups: motor symptoms and non-motor symptoms.
Early non-motor symptoms can be subtle and its possible to overlook them as signs of Parkinsons: for example, anxiety and depression, fatigue, loss of smell, speech problems, difficulty sleeping, erectile dysfunction, incontinence and constipation. Another sign of Parkinsons is handwriting that becomes smaller.
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How Is It Treated
At this time, there is no cure for Parkinson’s disease. But there are several types of medicines that can control the symptoms and make the disease easier to live with.
You may not even need treatment if your symptoms are mild. Your doctor may wait to prescribe medicines until your symptoms start to get in the way of your daily life. Your doctor will adjust your medicines as your symptoms get worse. You may need to take several medicines to get the best results.
Levodopa is the best drug for controlling symptoms of Parkinson’s. But it can cause problems if you use it for a long time or at a high dose. So doctors sometimes use other medicines to treat people in the early stages of the disease.
The decision to start taking medicine, and which medicine to take, will be different for each person. Your doctor will be able to help you make these choices.
In some cases, a treatment called deep brain stimulation may also be used. For this treatment, a surgeon places wires in your brain. The wires carry tiny electrical signals to the parts of the brain that control movement. These little signals can help those parts of the brain work better.
There are many things you can do at home that can help you stay as independent and healthy as possible. Eat healthy foods. Get the rest you need. Make wise use of your energy. Get some exercise every day. Physical therapy and occupational therapy can also help.
Diagnosing Early Onset Parkinsons Disease
There is no single test to detect Parkinsons. A diagnosis may be difficult and take a while. The condition is usually diagnosed by a neurologist based on a review of your symptoms and a physical exam.
A DaTscan to visualize your brains dopamine system may help confirm diagnosis. Blood tests and other imaging tests, such as an MRI scan, dont diagnose Parkinsons. However, they may be used to rule out other conditions.
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Tremor In Other Conditions
While tremor is a common symptom of Parkinsons, it can also be a symptom of other conditions, most notably essential tremor. The main difference between Parkinsons tremor and most other types of tremor is that in Parkinsons resting tremor is most common. Other conditions are usually characterized by action tremor, which tends to lessen at rest and increase when youre doing something, like trying to make a phone call or take a drink.
Tremors of the head and voice are also common in essential tremor but rare in Parkinsons.
When To See A Doctor
If you’re experiencing more than one of the above symptoms, ask your doctor about screening for Parkinson’s. “Unfortunately, making a PD diagnosisespecially in its early stagesis not easy,” says Beck. “There is not a simple blood test or brain scan that confirms a diagnosis. The presence of bradykinesia , plus either tremor or stiffness/rigidity, will help doctors make a PD diagnosis.”
If you’re diagnosed with Parkinson’s disease by an internist or geriatrician, the Parkinson’s Foundation “strongly recommends following up with a movement disorder specialist for a second opinion,” says Beck. “Movement disorder specialists are neurologists who have specific training in diagnosing and treating PD.” And to get through this pandemic at your healthiest, don’t miss these 35 Places You’re Most Likely to Catch COVID.
For more information, the Parkinson’s Foundation has many resources on its website, or you can call their helpline toll-free at 1-800-4PD-INFO.
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Parkinson’s Disease Is Difficult To Diagnose
Parkinson’s is a challenge to diagnose since there is no definitive test for it. Blood tests and scans are usually run just to rule out other causes of the symptoms.
If a GP suspects a patient could have Parkinson’s, they may refer them to a neurologist who can make a diagnosis based on medical history, a review of the signs and symptoms and a physical examination. It can help to keep a diary of symptoms leading up to the appointment.
Diagnosing Parkinson’s disease in some people can be a long process.
Causes Of Parkinson’s Disease
Parkinson’s disease is caused by a loss of nerve cells in the part of the brain called the substantia nigra.
Nerve cells in this part of the brain are responsible for producing a chemical called dopamine. Dopamine acts as a messenger between the parts of the brain and nervous system that help control and co-ordinate body movements.
If these nerve cells die or become damaged, the amount of dopamine in the brain is reduced. This means the part of the brain controlling movement can’t work as well as normal, causing movements to become slow and abnormal.
The loss of nerve cells is a slow process.;The symptoms of Parkinson’s disease;usually only start to develop when around 80% of the nerve cells in the substantia nigra have been lost.
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