Why Scientists Believe Theyve Made New Breakthrough In Parkinsons Disease Treatment By Building On Gdnf Research
The Finnish researchers are now working to improve the properties of BT13 to make it more effective as a potential treatment that could benefit many people living with the disease.
The study, which was published online yesterday in the journal Movement Disorders, builds on previous research on another molecule that targets the same receptors in the brain.
GDNF – or glial cell line-derived neurotrophic factor – is an experimental treatment for Parkinson’s discovered in 1993 that has been shown to bring dying brain cells back to life and particularly effective in dopamine neurons.
It was the subject of a BBC documentary in February 2019 that followed a phase two trial in Bristol involving 42 patients. While the results weren’t clear cut, GDNF has shown promise to restore damaged cells in people with Parkinson’s.
However, the GDNF protein requires complex robot-assisted surgery to deliver the treatment to the brain because it’s a large molecule that can’t cross the blood-brain barrier – a protective wall that prevents some drugs from getting into the brain.
BT13 is a smaller molecule that is able to cross the blood-brain barrier – and therefore could be more easily administered as a treatment if shown to be beneficial in further clinical trials.
Dr Yulia Sidorova, lead researcher on the study, said: “We are constantly working on improving the effectiveness of BT13.
“Our ultimate goal is to progress these compounds to clinical trials in a few coming years.”
Related Article
Roles Of Osmolytes In Protein Folding And Aggregation In Cells And Their Biotechnological Applications
names Mannitol as one of these bio-protective substances.
“Nature has selected osmolytes to protect intracellular macromolecules exposed to denaturing conditions and stabilize proteins. Osmolytes are small naturally occurring compounds that act as ‘chemical chaperones’ under changing environmental conditions and in disease states, and are present in microorganisms, animals, and plants. In the intracellular environment osmolytes naturally accumulate at high concentrations when cells/tissues are exposed to stressful conditions, which is important because protein aggregation, misfolding, and destabilization underlie the pathogenesis of several life-threatening neurodegenerative disorders. The ‘chaperone’ abilities of osmolytes suggests they may be therapeutically used for the treatment of several diseases associated with protein misfolding , and their abilities to protect proteins against stresses”
Specifically, the researchers say about Mannitol:
“Mannitol protects thiol-regulated enzymes such as thioredoxin, phosphoribulokinase, ferredoxin and glutathione from inactivation by ROS; quenches hydroxyl radicals and protects the enzymes inactivation by reactive oxygen species ;”
See
What’s Hot In Pd Update On The Use Of Mucuna Pruriens For The Treatment Of Parkinsons Disease
Selected References
Katzenschlager R, Evans A, Manson A, et al. Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study. J Neurol Neurosurg Psychiatry 2004;75:1672-77.
Latest News In Parkinson Disease: Treatment Progress Cognition Improvements And More
An overview of the latest news in Parkinson disease reported across MJH Life Sciences™.
An overview of the latest news in Parkinson disease reported across MJH Life Sciences™.
FDA Approves Investigational NDA for Ketamine in Levodopa-Induced Dykinesia
As the gold standard of treatment for PD, levodopa effectively reduces parkinsonian symptoms, although long-term use has been linked with several adverse events. Chief among these, frequency of OFF time and abnormal involuntary movements, known as levodopa-induced dyskinesia , have been shown to significantly impact quality of life and treatment efficacy.
There are no approved treatments to address LID; however, an article by NeurologyLive® indicates there may be some progress in addressing this issue. Last week, the FDA approved PharmaTher Holdings’ investigational new drug application for ketamine, an N-methyl-D-aspartate receptor-modulating drug, in the treatment of LID in patients with PD.
A phase 2 clinical trial evaluating the safety, efficacy, and pharmacokinetics of ketamine compared with the active control treatment of midazolam is expected to begin patient enrollment in the third quarter of this year. Pending success, the manufacturer noted that it will seek an agreement with the FDA to proceed to a phase 3 clinical study next year.
Novel Treatment Associated With Cognition Improvement in PD, Alzheimer Disease
Neurological Disease Link With COVID-19 Severity, Death
Natural Remedies And Treatments For Parkinsons Disease That Get Powerful Results
To successfully treat the symptoms of Parkinson’s, andeven reverse this disorder, there are 4 things you must do…
a) Increase your natural dopamine levels
b) Detox your body of all heavy metals andpollutants
c) Reduce all inflammation in the body,especially the brain
d) Repair the neuro pathways
These 10 natural treatments and remedies do all four. Solet’s not waste any more time then. Here they are in order of importance…
What’s Hot In Pd When Should You Start Medication Therapy For Parkinsons Disease
One of the most common questions that we receive on both on the Parkinson’s Foundation Ask the Doctor forum, and on the1-800-4PD-INFO Helpline is “when should I start medications for my Parkinson’s disease.” This months What’s Hot in PD column will focus on this simple, but critically important question.
The most important factor in initiating medications for an individual patient is whether Parkinson’s symptoms are affecting quality of life, or alternatively whether symptoms are affecting work performance. Bothersome Parkinson’s symptoms commonly include motor issues , and/or non-motor issues . Most experts agree that there is no benefit to delaying medication therapy if bothersome symptoms appear, and there may be risks in delaying treatment, especially if a treatment delay results in unsteadiness, falls, and fractures.
Over the last 10-20 years the thinking has evolved on when and how to initiate medication therapy for early Parkinson’s disease. Most experts agree that the medication dosage and the timing of the medication dosage should be carefully monitored in order to maximize the control of potentially responsive Parkinson related symptoms. The recommendation that patients should be started on dopamine agonist instead of levodopa has faded over the last decade, especially with the emergence of impulse control disorders and other dopamine agonist associated side effects.
New Treatment May Have The Potential To Slow Stop Or Reverse Parkinson Disease
Results from a recent study suggest that a revolutionary treatment may have the potential to slow, stop, or even reverse the progression of Parkinson disease.
Results from a February study of a revolutionary treatment suggest that it may be possible to slow, stop, or even reverse the progression of Parkinson disease, according to findings in the Journal of Parkinson’s Disease.
The 3-part, experimental study investigated whether using a novel delivery system to increase levels of glial cell line-derived neurotrophic factor can regenerate dying dopamine brain cells in patients with Parkinson disease and even reverse their condition. GDNF is a naturally occurring protein that promotes the survival of many types of neurons.
“I believe that this approach could be the first neuro-restorative treatment for people living with Parkinson’s, which is, of course, an extremely exciting prospect,” Steven Gill, MB, MS, FRCS, who designed the infusion device used in the study, said in a statement.
Initially, 6 patients enrolled in a pilot study which evaluated the safety of the treatment approach. After the pilot study, 35 additional individuals participated in a subsequent 9-month double-blind trial. Half of the participants were randomly assigned to receive monthly infusions of GDNF while the other half received placebos.
Reference
What Is Parkinsons Disease Symptoms Causes Diagnosis Treatment And Prevention
The causes and symptoms of Parkinson’s disease can vary from person to person. While there is no cure, there are medications and treatments to help manage the condition.
Parkinson’s disease is a movement disorder that happens when nerve cells in a certain part of the brain are no longer making the chemical dopamine.
The condition is also sometimes known as paralysis agitans or shaking palsy.
The Parkinson’s Foundation estimates that 60,000 Americans are diagnosed with Parkinson’s every year. However, the true number of people who develop the disease may be much higher.
Naturaltreatment For Parkinsons #9 Exercise And Other Alternative Therapies:
Regular exercise has been shown to help Parkinson’ssufferers by reducing muscle stiffness, increasing mobility, and enhancing postureand balance. Exercise also increases oxygen levels and neurotransmitters, alongwith releasing potent “mood elevating” chemicals called endorphins.
The type of exercise performed for PD is crucial. Aqua orwater aerobics can be particularly useful as traditional exercise is usuallyquite difficult for many Parkinson’s sufferers. Muscle decline, loss of strength,stiffness and loss of balance can make conventional exercises difficult toperform. The great thing about aqua aerobics is it still has the same benefits as other exercise regimens,but the risk of falling is eliminated.
Other types of exercises that can be beneficial for PDsufferers include Tai Chi, Yoga, dancing, walking, aerobic/jazzercise classes,and general stretching.
For more information on the different exercise programsavailable for Parkinson’s patients, you can check out this website… Exercise and Physical Therapy for Parkinson’sDisease
Homeopathy Doctor Near Me For Homeopathic Treatment For Parkinsons Disease
Since homeopathy belongs to a category of holistic medicine, all homeopathic doctors treat all diseases because homeopathic treatment applies to a patient, not to a disease. When you are looking for homeopathic practitioners, consider a homeopathic school. This physician graduated, experience, and online reviews. Homeopathy, similar to other holistic methods , is not something that any practitioner can do. In holistic medicine, never settle for less; get the best.
At the Philadelphia Homeopathic Clinic, internationally recognized homeopath, medical doctor Victor Tsan has 40+ years of academic and clinical experience. Contact our clinic 621-8485 to schedule your first appointment for a homeopathic evaluation with Dr. Tsan or do it online.
Natural Treatment For Parkinsons #3 Turmeric And Otherherbs And Spices:
A recent study published in the journal Stem Cell Research & Therapy, foundthat the extracts in turmeric, particularly curcumin and the newly discovered Ar-turmerone,can regenerate “a damaged brain” and reverse neurological disorders. Researchers said Ar-turmerone is “a promising candidate to supportregeneration in neurologic disease.” Michigan State University researcherBasir Ahmad also found that a compound in turmeric may help fight Parkinson’sdisease by disrupting the proteins responsible for the disease.
Another study published in the Pharmacognosy Magazine found that tumeric can prevent and evenreverse the toxic effects exerted on the brain from fluoride exposure. Fluorideis a nasty and dangerous heavy metal that destroys brain cells and the intricateworkings of the central nervous system. Fluoride poisoning has also beenimplicated in the development of neurological diseases such as Alzheimer’s,Parkinson’s, ALS and multiple sclerosis. 7
Turmeric is also a very potent anti-inflammatory spice. Because Parkinson’s is aninflammation type disease, turmeric will help immensely. A heaped teaspoon ofhigh quality turmeric powder taken 3 times daily in asmoothie will do the trick. Just make sure you combine it with 10-12 blackpeppercorns for enhanced absorption Turmeric is also fat soluble so you’ll need tocombine it with some coconut oil, red palm oil or fish/krill oil as well.
The Latest Research About Mucuna Pruriens As A Treatment For Parkinsons
In 2004, a study was conducted comparing the efficacy of MP with the standard medication used in PD, carbidopa/levodopa . Eight patients were given one dose of a MP preparation or C/L in a blinded fashion and then tested four hours after ingestion. MP acted more quickly and lasted longer than C/L without worsening of dyskinesias. A 2017 study also compared various single dose preparations of MP vs. C/L given blindly and determined that MP had a quicker onset of action, lasted longer and caused fewer dyskinesias.
However, when MP was given for longer periods of time as opposed to in single doses, the results were not as positive. In 2018, a study was conducted in which 14 patients were given MP powder for eight weeks and then carbidopa/levodopa for eight weeks. Seven of the patients discontinued MP, four for gastro-intestinal side effects and three for worsening of motor symptoms.
For the seven who remained on treatment, efficacy of MP was the same as C/L. Nobody discontinued during the C/L phase. Although the study showed that MP can be effective in reducing PD symptoms, it drew attention to the need for additional research into the optimal MP formulation and dose to allow for greater tolerability when taken continually.
H3: The difference between mucuna pruriens and cabidopa levodopa
How Can A Person With Pd Get A Supply Of Mp And What Is A Typical Dose
Interview With Clinical Research Scientist Prof Karen Raphael
Originally published on Tomorrow Edition on May 31, 2018
Surgery For Parkinsons Disease Is Another Approach To Help Patients
Deep brain stimulation is the popular surgical intervention that recently became one of the most recommended treatments for Parkinson’s disease due to the following reasons:
- It does not destruct brain tissue
- It is rescindable
- It can be altered and adjusted according to the phase of the disease.
- Bilateral interventions can be made without a substantial intensification in opposing events.
Massage The Most Popular Natural Treatment For Parkinsons Disease
Massage treatment can diminish muscle tension and helps to relax. This type of therapy, usually covered by health insurance if performed in physical therapy offices.
So, how massage therapy fits into the overall protocol for sustaining a healthy lifestyle for a person with Parkinson’s disease?
No wonder that massage therapy has been sought in PD for many years as an adjunct treatment to standard medical treatments.
One study by the National Institutes of Health details the different types of MT and the benefits in many areas for a patient with Parkinson’s disease.
Their study focused on reducing tremor and stiffness, which they actually saw a reduction. Other case studies observed in the NIH study discuss a reduction in pain, stiffness, constipation, less depression, and greater vitality! In addition, massage has been found to release the happy endorphins we need to fight depression and stop the pain!
Discuss The Latest Research In The Parkinsons News Today Forums
2. Carbidopa-levodopa infusion: In 2015, the FDA approved Duopa, which is a combination of carbidopa and levodopa in a gel form which is administered via a feeding tube into the small intestine.
Duopa is generally given to patients with advanced Parkinson’s disease whose response to carbidopa-levodopa is varied. The drug is infused continuously so the level of the drugs remains constant.
The risks associated with Duopa are infections at the site of the feeding tube and the tube falling out.
3. Dopamine agonists: Dopamine agonist mimic the effects of dopamine in the brain. They are generally not as effective as levodopa but the effects last longer and they can be used in conjunction with levodopa to counter any fluctuation in efficiency.
These medications can be administered through a patch, oral medications or as an injection. The side effects are also nausea and lightheadedness, but may also cause drowsiness, hallucinations and compulsive behaviors such as gambling, overeating, and hypersexuality — which will need to be addressed by a doctor.
MORE: Find out about the four possible causes of Parkinson’s disease here.
4. MAO-B inhinitors: Medications such as selegiline and rasagiline help to prevent dopamine breaking down in the brain by releasing monoamine oxidase B enzymes.
5. Catechol-O-methyltransferase inhibitors: These types of medications help to prolong the effects of levodopa by blocking brain enzymes that deplete dopamine.
What Are The Latest Approved Treatments For Parkinsons Disease
Several medicines have been approved for the treatment of Parkinson’s disease. Here are some of the available medicines for Parkinson’s disease:
Nuplazid 3,4
Nuplazid was approved for the treatment of patients with hallucinations and delusions associated with Parkinson’s disease psychosis by the Food and Drugs Administration on April 29, 2016. On December 3, 2020 The approved an update to the prescribing information for Nuplazid that will allow the medication to be taken more easily by Parkinson’s patients who have difficulty swallowing.
Ongentys 5,6
Ongentys is a medication used for the treatment of Parkinson disease. It is indicated for the treatment of adult patients with Parkinson disease. It is used as an add-on to levodopa/DOPA decarboxylase inhibitors in patients who are having fluctuations in the control of their condition.
Opicapone was approved for treating patients with Parkinson’s Disease as an add-on to levodopa/DOPA decarboxylase inhibitors in patients who are having fluctuations in the control of their condition by the European Medicines Agency on June 24, 2016 and by the Food and Drug Administration on April 24, 2020.
Nourianz/Nouriast 7,8,9
Nourianz/Nouriast was approved by the Food and Drug Administration , USA, on August 27, 2019 and by the Pharmaceuticals and Medical Devices Agency , Japan, in June 2013.
Inbrija 10,11,12
Natural Treatment For Parkinsons #1 Cannabis/medicalmarijuana:
Cannabis, aka medical marijuana, is an incredibletreatment for Parkinson’s disease. You can have a Parkinson’s patient shakingviolently and uncontrollably, and yet within 30-40 minutes of self-administering with some cannabis, their symptoms will almost completely disappear. Watch this short 2minute video from Parkinson’s sufferer, Ian Frizell, who shows you what he waslike before self-medicating with cannabis and then again after. The change is truly astonishing!
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Taylor French is another Parkinson’s patient thatundergoes a remarkable transformation once he ingests what he calls “nutritional vegetable extract” . This guy has an advanced form ofParkinson’s and is normally confined to a wheelchair with limited use of hisbody due to stiff and rigid muscles . But after ingestingsome cannabis he’s able to walk, and incredibly, in his video he even getsinto his car and drives off down the road!
You can view it here…
Elyse Del Francia also tells the story of her Parkinson’ssuffering husband, and the time she decided to smother his morning pancakes withsome canabutter. She said…
“Within45 minutes of eating a pancake with marijuana on it, he stopped shaking. Thatwas my lightbulb moment. That’s when I knew that I was onto something thatwould relieve his pain and suffering, because it’s horrible, horrible, to haveParkinson’s Disease and not have any relief. I feel that this is something thathelps so many people in so many ways with pain and suffering.” 5
What Lifestyle Changes Can I Make To Ease Parkinsons Symptoms
Exercise: Exercise helps improve muscle strength, balance, coordination, flexibility, and tremor. It is also strongly believed to improve memory, thinking and reduce the risk of falls and decrease anxiety and depression. One study in persons with Parkinson’s disease showed that 2.5 hours of exercise per week resulted in improved ability to move and a slower decline in quality of life compared to those who didn’t exercise or didn’t start until later in the course of their disease. Some exercises to consider include strengthening or resistance training, stretching exercises or aerobics . All types of exercise are helpful.
Eat a healthy, balanced diet: This is not only good for your general health but can ease some of the non-movement related symptoms of Parkinson’s, such as constipation. Eating foods high in fiber in particular can relieve constipation. The Mediterranean diet is one example of a healthy diet.
Preventing falls and maintaining balance: Falls are a frequent complication of Parkinson’s. While you can do many things to reduce your risk of falling, the two most important are: 1) to work with your doctor to ensure that your treatments — whether medicines or deep brain stimulation — are optimal; and 2) to consult with a physical therapist who can assess your walking and balance. The physical therapist is the expert when it comes to recommending assistive devices or exercise to improve safety and preventing falls.
Improve the quality of your sleep.
Current Parkinsons Treatments Cant Slow Down Onset Of Disease
Parkinson’s is a long-term degenerative disorder of the central nervous system, which mainly the area of the brain that controls movement – leading to a slow onset of symptoms including tremors, rigidity and slow movement.
More than 10 million people worldwide are estimated to be living with Parkinson’s disease, according to the US-based Parkinson’s Foundation, with the Parkinson’s News Today website saying it affects 1,900 per 100,000 among those aged over 80,
Typically, by the time people are diagnosed with the condition, they have already lost between 70% and 80% of their dopamine-producing cells, which are involved in co-ordinating movement.
While current treatments mask the symptoms, there is nothing that can slow down its progression or prevent more brain cells from being lost.
As dopamine levels continue to fall, symptoms get worse and new symptoms can appear.
Scientists Are Close To Finding A Cure For Parkinsons Disease
Researchers studied mutant fruit flies to uncover how the disease affects the brain
SCIENTISTS are on the brink of finding a cure for Parkinson’s disease after discovering what causes the illness and how it affects brain cells.
Experts previously thought people who fell ill at a younger age than most who develop Parkinson’s suffer from a poorly functioning ‘mitochondria’.
These are the powerhouses of cells and without reliable sources of energy, neurons wither and die.
But Medical Research Council researchers at University of Leicester found this may not be the complete picture of what is happening within the brain cells affected by Parkinson’s.
Now it is thought neuro deterioration occurs in response to stress on the endoplasmic reticulum – part of the outer skin of the cell – rather than failure of the mitochondria as previously thought.
During the study fruit flies were injected with chemicals to prevent the effects of ER stress and as a result, it prevented the death of neurons which are commonly associated with the disease.
Dr Miguel Martins said: “This research challenges the current held belief that Parkinson’s disease is a result of malfunctioning mitochondria.
“By identifying and preventing ER stress in a model of the disease it was possible for us to prevent neurodegeneration.
“Lab experiments, like this, allow us to see what effect ER stress has on Parkinson’s disease.
Leicester’s MRC Toxicology unit in Leicester carried out the experiment.
- Topics
Parkinsons Disease Natural Treatment & Remedies In 5 Steps
April 17, 2018
Parkinson’s disease is a degenerative illness of the nervous system that results in loss of intentional movement and impaired motor functioning. Parkinson’s disease symptoms affects smooth, natural movements of the body, and can make it hard to perform everyday tasks like speaking properly, walking, swallowing and sleeping.
With Parkinson’s, the area of the brain that controls muscular movements receives less dopamine than usual. Dopamine is an important chemical necessary for not only coordinating proper body movements, but also things like learning, increasing motivation and regulating moods. This is one reason why depression and other mood changes often affect those with Parkinson’s.
What causes Parkinson’s, and is it curable? There is no specific known cause, but some aggravating factors include exposure to certain chemicals and toxic water, plus inflammation of the brain. While there is no cure for Parkinson’s , there are medications available to boost dopamine in the brain and help manage symptoms.
A 2016 study by researchers at the University of Saskatchewan also found a possible way to stop the progression of Parkinson’s. Researchers created caffeine-based chemical compounds — which also contained nicotine, metformin and aminoindan — that prevented the misfolding of alpha-synuclein, a protein necessary for dopamine regulation.
Protein Identified That May Help Treat Parkinsons Disease
Scientists have identified a protein that can slow or stop some signs of Parkinson’s disease in mice.
The team found that the bone morphogenetic proteins 5 and 7 can have these effects in a mouse model of the disease.
This research, which appears in the journal Brain, may be the first step toward developing a new treatment for Parkinson’s disease.
This type of brain disorder typically affects people over the age of 60, and the symptoms worsen with time.
Common symptoms include stiffness, difficulty walking, tremors, and trouble with balance and coordination.
The disease can also affect the ability to speak and lead to mood changes, tiredness, and memory loss.
Parkinson’s Foundation report that about 1 million people in the United States had the disease in 2020, with about 10 million affected globally.
Despite this prevalence, scientists are still unsure why Parkinson’s disease affects some people and not others, and there is currently no cure.
The National Institute on Aging note that some cases of Parkinson’s disease seem to be hereditary. In other words, the disease can emerge in different generations of a family — but for many people with the disease, there appears to be no family history.
Researchers believe that multiple factors may affect a person’s risk, including genetics, exposure to environmental toxins, and age.
Since there is currently no cure for Parkinson’s disease, treatments typically focus on alleviating its symptoms.
Natural Remedies And Treatments For Parkinsons Finalnote
So there you have our top 10 natural remedies andtreatments for reversing Parkinson’s disease. We believe this is one of the most informative andthorough health articles on this disease you’ll find anywhere on the internet. Ifyou follow these 10 tips to-the-letter and continue to use them consistently,we guarantee that in 3-6 months’ time you will be truly astounded at themiraculous level of improvement you’ll see. In 12 months’ time you will scarcely recognize yourself! . But of course, you must stickwith them and follow through with each remedy every day if you want them towork. We sincerely hope you do.
Good luck and best wishes.
P.S. Because Parkinson’s is closely linked to Alzheimer’s disease and actually goes under the “dementia umbrella”, we recommend you take the time to read our “Powerful Natural Remedies for Dementia and Alzheimer’s” article for a more complete and comprehensive understanding on the causes and treatments for these diseases. You can click on the link below to go there…
Surgical Therapies With Transplantation And Gene Therapy
Cell transplantation is regarded as a potential future PD treatment. There have been trials using autologous and non-autologous cells. Human embryonic stem cells and induced pluripotent stem cells are few of the cells that have been included in these transplantation studies. One of the concerns with cell transplantation using stem cells is the ethical bounds that must be considered.
Since the first clinical trial in 1987 involving the transplantation of dopaminergic- neuron-rich human fetal mesencephalic tissue into PD patients’ striatums, more research has aimed to explore whether the grafted dopaminergic neurons will live and form connections in the brain, if the patient’s brain can harmonize and make use of the grafted neurons, and if the grafts can generate significant clinical improvement. Clinical trials with cell therapy intend to discover if there are long-lasting improvements following restoration of striatal DA transmission by grafted dopaminergic neurons. Experimental data from rodents and nonhuman primates show that fetal ventral mesencephalon intrastriatal grafted DA neurons demonstrate many morphological and functional characteristics of normal DA neurons. Significant improvements of PD-like symptoms in animal models have been demonstrated after successful reinnervation by the grafts. Dopaminergic grafts can reinnervate the striatum in the brain, restore regulated release of DA in the striatum, and can become functionally integrated into neural circuitries.
What Are The Surgical Treatments For Parkinsons Disease
Most patients with Parkinson’s disease can maintain a good quality of life with medications. However, as the disease worsens, medications may no longer be effective in some patients. In these patients, the effectiveness of medications becomes unpredictable – reducing symptoms during “on” periods and no longer controlling symptoms during “off” periods, which usually occur when the medication is wearing off and just before the next dose is to be taken. Sometimes these variations can be managed with changes in medications. However, sometimes they can’t. Based on the type and severity of your symptoms, the failure of adjustments in your medications, the decline in your quality of life and your overall health, your doctor may discuss some of the available surgical options.
What Is The Outlook For Persons With Parkinsons Disease
Although there is no cure or absolute evidence of ways to prevent Parkinson’s disease, scientists are working hard to learn more about the disease and find innovative ways to better manage it, prevent it from progressing and ultimately curing it.
Currently, you and your healthcare team’s efforts are focused on medical management of your symptoms along with general health and lifestyle improvement recommendations . By identifying individual symptoms and adjusting the course of action based on changes in symptoms, most people with Parkinson’s disease can live fulfilling lives.
The future is hopeful. Some of the research underway includes:
- Using stem cells to produce new neurons, which would produce dopamine.
- Producing a dopamine-producing enzyme that is delivered to a gene in the brain that controls movement.
- Using a naturally occurring human protein – glial cell-line derived neurotrophic factor, GDNF – to protect dopamine-releasing nerve cells.
Many other investigations are underway too. Much has been learned, much progress has been made and additional discoveries are likely to come.
Homeopathic Treatment For Parkinsons Disease By Dr Tsan
Mercurius Solubilus – in experimentally induced Dementia in rats, this homeopathic remedy progresses cerebral blood flow and memory. Mercurius is the most common Homoeopathic Treatment forParkinson’s disease.
A weakness of arms and legs, unsteady gait, and especially shaking hands are the most common symptoms for which homeopathic doctors will prescribe it.
Zincum Metallicum is another common homeopathic remedy forParkinson’s disease when Violent shaking of the whole body as a result of stress and emotional events is the main manifestation of the disease.
focusing on the central nervous system and thus triggering different levels of paralysis as well as sleepiness, tiredness, dreariness, and trembling. On the list of the most common homeopathic remedies forParkinson’s disease,Gelsemium will take 3rd place.
Naturaltreatment For Parkinsons #6 Magnesium & Iodine:
Magnesium is vital for the health of the entire nervoussystem, especially the protective layer that surrounds the nerves . Magnesiumis also essential for the production of dopamine and helps protect dopaminergicneurons in the substantia nigra from degeneration. In addition to this, new evidence is showing that low levels of magnesium in the brain causes a build-up ofheavy metals – a major factor in the development of Parkinson’s, Alzheimer’s,epilepsy and MS. In a recent trial, 30 epileptics were given 450 mg ofmagnesium daily and this successfully controlled their seizures. Ifmagnesium can help epilepsy patients, it can certainly help Parkinson’s sufferers. Worldrenowned magnesium expert and author, Dr Carolyn Dean, has both Parkinson’s andAlzheimer’s disease in her “top 55 health conditions caused by amagnesium deficiency” list and says that magnesium is 100% essential for the preventionand treatment of both of these diseases… Dr Carolyn Dean Interview
In regards to iodine, well-known researcher and author,Dr James Howenstein, says…
“Iodineis found in large quantities in the brain and the ciliary body of the eye. A lackof iodine may be involved in the production of Parkinson’s disease andglaucoma.”
“Inthe brain, iodine concentrates in the substantia nigra, an area of the brainthat has been associated with Parkinson’s disease.”
David Brownstein M.D. 9
Best Sources of Magnesium and Iodine…
-What You’ll Need
1 cup of Magnesium Chloride Flakes
1 cup of Distilled Water