Why Do I Get Constipated
We are still learning about constipation in PD and why it happens. Here is what we know:
The same changes that occur in brain cells in Parkinsons disease may also occur in nerve cells in the spinal cord and the intestinal wall. These changes may slow down the muscles that push food through the intestines.
Medications used to treat PD in particular, the class called anticholinergics and the medication amantadine, used to treat dyskinesia are known for causing constipation. If you are on these medications, your healthcare provider may be able to reduce your dose or switch you to a different one. But for some people, the benefits of the medication outweigh the possibility of constipation.
Because people with Parkinsons disease experience difficulty with their movement, they often become less active. People with PD who increase their movement experience better overall functioning, which includes their digestive system.
Many people with Parkinsons disease limit their fluids to avoid making frequent trips to the bathroom. When a person drinks less liquid, the gut may not have the lubrication it needs to have a bowel movement, which contributes to constipation.
It is possible to have a family predisposition to constipation. Ask family members what solutions work for them. Your body may respond to the same strategies.
Individual Body Chemistry
Constipation And Hydration In Parkinsons Disease
As Parkinsons disease can cause constipation, the Parkinsons Foundation recommends a diet featuring 20 to 25 grams of daily fiber to maintain bowel health.
Its really important for overall health to keep bowels moving, Subramanian says. We recommend a diet with a lot of vegetables and as much fiber as you can take. Foods that are high in prebiotics, including fermented foods like sauerkraut and kimchee, can also help.
Some Parkinsons disease medications dont work as well when taken with fermented foods, however, so check with your doctor before incorporating them into your diet.
Proper hydration is also important for everyone, including people who have Parkinsons disease. Try to drink six to eight glasses of water a day and take your medications with a full glass of water, the Parkinsons Foundation notes. It may help your body break down the medication more efficiently.
Hydration helps with blood pressure and constipation, Subramanian notes. We recommend our Parkinsons patients drink 40 ounces of water a day. Thats just water, not coffee or tea or other drinks. This can also help improve digestion.
If drinking water leads to urinary urgency, try eating foods with a high water content like celery, butternut squash, grapefruit, strawberries, and watermelon instead.
Parkinsons Disease: Combating Constipation
In Part 2 of this 3-part blog series we discuss constipation related to Parkinsons disease and the gut-brain connection.
In patients with Parkinsons disease, the major cause of constipation is that the nervous system control of the gut slows down due to the effects of the disease, resulting in the slowing down of gut movement and leading to constipation.
Alpha-synuclein refers to the abnormal protein that is also seen in the brains of patients with PD. These same protein deposits have been observed in the gut prior to development of motor symptoms, up to 20 years prior to diagnosis. These abnormalities have also been found in the parasympathetic neurons of the vagus and sacral nerves that connect the brain to the visceral organs and are involved in the autonomic nervous system. The term parasympathetic refers to the side of the autonomic nervous system that allows the gut to move . Basically as the nervous system control of the gut slows, gut function slows and constipation results.
Interestingly, patients self-reports of constipation may not paint the full picture of the severity of constipation. One study found that objective measurements of colon transit time revealed higher rates of constipation than subjectively reported by patients. This is known as slow transit constipation.
Patients with PD should be aware of their bowel movements and remain vigilant to the development of constipation and should do the following to improve bowel regularity:
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Best Laxative For Heart Patients
Laxatives are a common and effective treatment for constipation. They work by softening the stool and increasing the number of bowel movements. This can help to relieve the symptoms of constipation, such as pain, bloating, and difficulty passing stool.
There are a variety of laxatives available, including over-the-counter and prescription options. Some laxatives are taken orally, while others are taken rectally. The type of laxative that is best for a heart patient will depend on the severity of the constipation and the individuals preferences.
If constipation is severe or persists despite the use of laxatives, it is important to see a doctor. Constipation can be a sign of a more serious underlying condition, such as an obstruction in the intestines.
Recommendations On Safe Laxative Use
Safe laxative practices are important to avoid potential harms.
First, always follow the advice of your medical professional regarding product type, dosing and duration. Most laxatives are not intended for long-term use.
Laxatives are generally safe for people over the age of 12, but be sure to avoid certain laxatives not intended for specific populations .
Be sure to use laxatives with at least six to eight cups of additional water to avoid dehydration.
Summary: Use laxatives as instructed and stay adequately hydrated.
Taking Your Drugs And Food Together
Levodopa is the best medication for Parkinsonâs. Ideally, you should take it on an empty stomach, about 30 minutes before eating or at least one hour after a meal. But that can cause nausea in some people. Your doctor may prescribe something else or a different mix of drugs, which may not always make the nausea go away. In that case, your doctor may recommend you take medication for your side effects.
Also, ask your doctor if you should cut down on protein. In rare cases, a high-protein diet can make levodopa work less well.
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Other Treatments Options For Constipation
While laxatives often provide a quick fix for constipation, they are not your only option.
Try some of these diet and lifestyle changes to address constipation:
- Consume plenty of fiber-rich foods like whole grains, legumes, vegetables and fruits
- Drink more fluids, especially water
- Exercise regularly
To learn more, check out this extensive article on proven remedies for chronic constipation.
Summary: Diet and lifestyle changes are important components in constipation prevention and treatment.
Miralax Powder Laxative 45 Doses 269 Ounce
Miralax works with your bodys natural process to provide effective relief from occasional constipation. Because it works with the body, Miralax provides a gentle experience, and doesnt cause harsh side effects such as gas, bloating, cramping, or sudden urgency.
Miralax easily dissolves completely in four to eight ounces of water, fruit juice, or any other beverage.
How Serine Prevents Bmaa Toxicity
BMAA produces its brain-damaging effects by causing an altered shape of brain proteins by replacing the L-serine. Basically, brain cells mistake BMAA and its more toxic form nitroso-BMAA for L-serine and when they replace BMAA for L-serine in the proteins the brain cell manufactures it leads to a protein that is not shaped the way that it should be leading to a degeneration of the protein and toxicity to brain cells. The proteins are not folded properly. They are either folded in odd ways or not folded at all. Much of the initial research was done by scientists working at Coxs Brain Chemistry Labs in Jackson Hole, Wyoming.
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How To Deal With It
Like other symptoms of Parkinsons, constipation should also be treated properly. Because if not treated properly, it can lead to a number of other problems in patients. For example, it can cause abdominal pain, nausea, bloating, vomiting, and weight loss. In some patients it also lead to intestinal obstruction and bleeding.
So here are 4 ways that you can use to deal with constipation!
First Try Psyllium Husk A Natural Laxative
Bulk-forming laxatives are typically the first line of therapy for those with constipation or IBS-C.
However, its important to know that the fermentability of the fiber makes a difference in its ability to improve symptoms.
Overall, its best to pick soluble, non-fermenting fiber like psyllium husk, which is a low-risk, highly effective laxative option .
In a study comparing psyllium husk and docusate sodium on 170 subjects for 2 weeks, researchers found psyllium to be superior in its ability to soften stools and produce a laxative effect .
In fact, there is poor evidence supporting the use of docusate to treat constipation, with some concern over its occasional impact on liver function.
Mineral oil also has insufficient data for its use in constipation and numerous reports of undesired side effects and poor tolerability.
Overall, for occasional and mild constipation, its best to start treatment with psyllium fiber .
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What Is Parkinsons Disease
Parkinsons disease is a chronic, degenerative neurological disorder that affects older people most often, and men more often than women. Its believed to be caused by a combination of both genetic and environmental factors.
Characteristics of Parkinsons include tremors, muscle stiffness, poor balance and difficulty walking. Although symptoms vary from person to person, with time simple tasks like getting dressed in the morning or going to work can often become a chore.
Because Parkinsons disease is a chronic condition, symptoms usually persist over a long period of time and also progress with age. Each Parkinsons patient is different, so its common to experience varying levels of different symptoms. For this reason, some patients respond better to certain natural treatments than others.
Rectal Enemas & Suppositories
This type of laxative mechanically stimulates the rectum to help empty the bowels.
Enemas are either water or salt solutions that are pushed into the rectum via a prepared enema, enema bulb or fountain syringe.
They are highly effective at improving constipation, typically within 2 to 15 minutes, but may cause intense urgency, bloating and cramping.
Suppositories work slightly differently than enemas by irritating the bottom of the intestine, causing it to contract. They can also stimulate the intestines to secrete more water and salt, which helps soften stool.
Examples include Glycerine and Fleets Phosphosoda.
Summary: There are numerous laxatives available to help relieve constipation. Many work by softening or moisturizing stool or by stimulating the digestive tract muscles. While most are generally safe for short-term use, its important to talk to your doctor to find out which laxative is best suited for you.
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Certain Foods And Drinking Not Enough Water
Eating certain foods can cause Parkinsons patients to be constipated. It could be a specific food or a combination of different things. Drinking not enough water can also be the reason for the body to be constipation. If the body is not properly hydrated, the stool becomes hard and makes it difficult for the colon to pass it through.
Follow A Squatty Potty Posture In The Toilet
A proper posture while sitting on the commode in the toilet is very important for controlling constipation. But this is ignored by most people.
We usually follow a slump posture while sitting in the toilet. This position is not good for proper elimination as it makes a kink in the rectum and restrains the outward movement of bowel which makes the constipation more worsen.
To avoid this, researchers recommend following a squatty potty posture. In this posture, your sitting position makes an angle in a way where your knees are above your hips, the same like you do squats. This position makes the rectum like a shoot that allows the bowel to eliminate out the stool more easily.
Using a western toilet commode can make it very hard to get into squatty potty position. However, a toilet stool can make it easier for you. So use a small stool available in your house that allows to raise your knees above your hips and make it to a squatty position when sitting in the toilet. You can also buy a squatty potty stool, which is especially designed for squatty potty position.
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The Importance Of Diagnosing Depression
Treatment of depression in patients with PD may significantly slow cognitive decline, deterioration in Activities of Daily Living and progression to the more advanced of the Hoehn and Yahr stages. A longitudinal study by Starkstein and colleagues showed that patients with major depression and PD showed a significantly greater decline in ADLs over a 1-year period than patients with PD with minor depression only or no depression. Patients with major depression and PD had significantly longer durations of illness, but when patients were matched for duration and followed longitudinally, those with major depression worsened to a significantly greater extent. Cost-benefit analyses of antidepressant treatment in patients with PD are urgently needed.
Drink Plenty Of Water
Drinking plenty of water is important for all Parkinsons patients, but it is even more important for those who frequently experience constipation.
Research suggests that drinking not enough water is the main reason of constipation in Parkinsons disease. A study in patients with Parkinsons disease conducted in Japan showed that decreased water intake from early life was strongly linked to constipation in patients.
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New Jnnp Online Submission And Review System
The Editors of JNNP are pleased to inform authors and reviewers of its new online submission and review system. Bench> Press is a fully integrated electronic system which uses the internet to allow rapid and efficient submission of manuscripts, plus the entire peer review process to be conducted online.
To access the system click on SUBMIT YOUR MANUSCRIPT HERE on the JNNP homepage: , or you can access Bench> Press directly at .
We are very excited with this new development and we would encourage authors and reviewers to use the on-line system where possible. It really is simple to use and should be a big improvement on the current peer review process. Full instructions can be found on Bench> Press and JNNP online at . Please contact Natalie Davies, Project Manager, ndaviesbmjgroup.com for further information.
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Addressing Practical Aspects Of Eating And Drinking
Some people with Parkinsons have problems chewing and swallowing. This can make it difficult to eat a diet with plenty of fibre. A speech and language therapist can give advice about this. Ask your GP, specialist or Parkinsons nurse for a referral. If it takes a long time to eat and your meal goes cold, eat smaller portions and go back for seconds that have been kept warm. You can also get special plates that keep your meals hot the Disabled Living Foundation has more information.
An occupational therapist will also be able to give you some tips and practical advice.
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Natural Remedies For Parkinson Disease
Uncontrollable tremors, memory loss, foggy thoughts, sleep disruptions, difficulty to speak Parkinsons Disease is a severe condition that degrades the life quality of millions around the world. Conventional medicine can be helpful, but many people who suffer from the disease dont enjoy the side effects or the thought of consuming chemicals on a daily basis.
Parkinsons disease is a degenerative illness of the nervous system that results in loss of intentional movement and impaired motor functioning. Parkinsons disease symptoms affects smooth, natural movements of the body, and can make it hard to perform everyday tasks like speaking properly, walking, swallowing and sleeping.
With Parkinsons, the area of the brain that controls muscular movements receives less dopamine than usual. Dopamine is an important chemical necessary for not only coordinating proper body movements, but also things like learning, increasing motivation and regulating moods. This is one reason why depression and other mood changes often affect those with Parkinsons.
What causes Parkinsons, and is it curable? There is no specific known cause, but some aggravating factors include exposure to certain chemicals and toxic water, plus inflammation of the brain. While there is no cure for Parkinsons , there are medications available to boost dopamine in the brain and help manage symptoms.
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