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What Treatment For Parkinson Disease

Who Does It Affect

Parkinson’s Disease Symptoms, Treatment, Nursing Care, Pathophysiology NCLEX Review

The risk of developing Parkinsons disease naturally increases with age, and the average age at which it starts is 60 years old. Its slightly more common in men or people designated male at birth than in women or people designated female at birth .

While Parkinsons disease is usually age-related, it can happen in adults as young as 20 .

Support For People With Parkinsons Disease

Early access to a multidisciplinary support team is important. These teams may include doctors, physiotherapists, occupational therapists, speech therapists, dietitians, social workers and specialist nurses.

Members of the team assess the person with Parkinsons disease and identify potential difficulties and possible solutions.

There are a limited number of multidisciplinary teams in Victoria that specialise in Parkinsons disease management. But generalist teams are becoming more aware of how to help people with Parkinsons disease.

Does Cbd Help Parkinsons

CBD hasnt been used in Parkinsons Disease patients long term, and there are few studies to rely on for treatment guidance. Recently, a Phase II clinical trial was completed on CBDs role in the treatment of Parkinsons Disease. Treatment outcomes were positive for sleep, depression, behavior and emotion, anxiety, and cognition. Improvements in psychotic features were seen as well.

About 20-40% of PD patients experience psychotic symptoms. And, treatment with antipsychotics may bring out Parkinson-like symptoms. Taking CBD may relieve pain associated with PD, although research favors THC for this effect.

CBD oil for Parkinsons symptom treatment can be in the form of edibles, oils, tinctures, ointments, vape cartridges, and creams. Topical CBD can be used for muscle spasms so common in patients with PD, and oils can be used to relieve symptoms faster.

However, data is lacking regarding this mode of delivery. Tinctures also offer speedy effects as a way to take CBD. The only FDA-approved way of taking CBD, however, is through the drug Epidiolex although its benefits have been shown from other CBD oils.

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A New Era For Parkinsons Disease Treatment

March 2, 2022 | By

A non-invasive ultrasound treatment for Parkinsons disease that was tested in a pivotal trial led by University of Maryland School of Medicine researchers is now broadly available at the University of Maryland Medical Center .

Howard Eisenberg, MD, Dheeraj Gandhi, MD, MBBS, Paul Fishman, MD, PhD, Bert W. OMalley, MD.

The device, called Exablate Neuro, was approved in November by the U.S. Food and Drug Administration to treat advanced Parkinsons disease on one side of the brain. The approval was based on findings from the UMSOM clinical trial and effectively expands access to focused ultrasound beyond clinical trial participation.

Rapid Reversal of Symptoms

Focused ultrasound is an incisionless procedure, performed without the need for anesthesia or an in-patient stay in the hospital. Patients, who are fully alert, lie in a magnetic resonance imaging scanner, wearing a transducer helmet. Ultrasonic energy is targeted through the skull to the globus pallidus, a structure deep in the brain that helps control regular voluntary movement. MRI images provide doctors with a real-time temperature map of the area being treated. During the procedure, the patient is awake and providing feedback, which allows doctors to monitor the immediate effects of the tissue ablation and make adjustments as needed.

Patient: Focused Ultrasound Changed My Life

A New Era for Parkinsons Disease Treatment

Parkinsons Disease Natural Treatment & Remedies In 5 Steps

Pharmaceutical Treatment of Parkinson

By Dr. Josh Axe, DC, DNM, CN

Parkinsons disease is a degenerative illness of the nervous system that results in loss of intentional movement and impaired motor functioning. Parkinsons disease symptoms affects smooth, natural movements of the body, and can make it hard to perform everyday tasks like speaking properly, walking, swallowing and sleeping.

With Parkinsons, the area of the brain that controls muscular movements receives less dopamine than usual. Dopamine is an important chemical necessary for not only coordinating proper body movements, but also things like learning, increasing motivation and regulating moods. This is one reason why depression and other mood changes often affect those with Parkinsons.

What causes Parkinsons, and is it curable? There is no specific known cause, but some aggravating factors include exposure to certain chemicals and toxic water, plus inflammation of the brain. While there is no cure for Parkinsons , there are medications available to boost dopamine in the brain and help manage symptoms.

A 2016 study by researchers at the University of Saskatchewan also found a possible way to stop the progression of Parkinsons. Researchers created caffeine-based chemical compounds which also contained nicotine, metformin and aminoindan that prevented the misfolding of alpha-synuclein, a protein necessary for dopamine regulation.

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Important Points About The New Medications

With multiple new medications available for the treatment of PD, there is more hope than ever that Parkinsons symptoms can be successfully managed for many years. A few things to consider:

  • For people whose symptoms are difficult to control, these new treatments are welcome additions to what was previously available and many people with PD have been using these new medications with significant benefit.
  • On the other hand, many of the newly-approved medications have the same mechanisms of action as older medications so they are not breaking new ground in treating symptoms.
  • In addition, for some people, the effect on symptoms may be mild or not substantial.

These caveats may mean that your physician has not suggested a medication change for you. It is also important to note that despite all the new medications, carbidopa/levodopa remains the most potent medication to treat the motor symptoms of PD.

If your doctor does choose to try one of the new options, there may be multiple paths that your doctor can take when contemplating a medication adjustment. Often trial and error is the only way to determine the best medication regimen for you, so you may need to practice some patience as you work together with your doctor to determine what works or doesnt work.

Diagnosis And Management Of Parkinsons Disease

There are no diagnostic tests for Parkinsons. X-rays, scans and blood tests may be used to rule out other conditions. For this reason, getting a diagnosis of Parkinsons may take some time.

No two people with Parkinsons disease will have exactly the same symptoms or treatment. Your doctor or neurologist can help you decide which treatments to use.

People can manage their Parkinsons disease symptoms through:

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When To Seek Professional Help For Parkinsons Symptoms

Parkinsons is a debilitating disease that when left unchecked can leave you with little to no control over your body. Even though there is no cure for Parkinsons disease the earlier you are diagnosed the more likely you are to live your life without severe symptoms. By intervening early with these natural Parkinsons treatment options – and/or medication depending on your health case – you have a greater chance of slowing down the progression of this disease and your symptoms.

If you have a family history of Parkinsons it’s important to consider genetic testing to assess your risk factor, especially if you have any of the symptoms or early signs of this disease.

If you are currently diagnosed with Parkinsons disease and are interested in how you can treat this condition naturally, schedule a telehealth consultation for personalized treatment with functional medicine.

As one of the first functional medicine telehealth clinics in the world, we provide webcam health consultations for people around the globe.

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

BY DR. WILL COLE

Evidence-based reviewed article

The Best Alternative Treatments For Parkinsons

Vibrating gloves could counteract Parkinson’s disease

Research is continuing to examine the mechanisms behind Parkinsons to find possible cures and ways to ease symptoms. Because of this extensive research, there are many promising natural Parkinsons treatment options. While our knowledge around these Parkinsons natural treatment options are still evolving, these are supported by the most research.

1. Cannabis

Currently, cannabis is the natural treatment for Parkinsons that is getting the most attention, and for good reason. Also known as marijuana, cannabis contains cannabinoid compounds like THC – the one with the psychoactive properties – and CBD that includes many of the health benefits of THC but without the psychoactive properties.

Early studies on both THC and CBD have found cannabis to be a promising therapy for improved motor function and neuroprotection in patients with Parkinsons. As anecdotal evidence for cannabis and Parkinsons continues to emerge, it has prompted more research to be done on its effects.

2. Diet

In functional medicine, we understand that food is foundational and the foods you eat on a daily basis can either fuel disease or facilitate health. Multiple studies have connected the ketogenic diet – a high-fat, moderate protein, low-carb diet – to significant improvement in Parkinsons disease symptoms.

3. Acupuncture

4. COQ10

5. Massage therapy

6. Tai chi

7. Aromatherapy

8. Hydrotherapy

9. Alexander Technique

10. Yoga

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Symptoms Of Parkinsons Disease

Parkinsons has four main symptoms:

  • Tremor in hands, arms, legs, jaw, or head
  • Muscle stiffness, where muscle remains contracted for a long time
  • Slowness of movement
  • Impaired balance and coordination, sometimes leading to falls

Other symptoms may include:

The symptoms of Parkinsons and the rate of progression differ among individuals. Early symptoms of this disease are subtle and occur gradually. For example, people may feel mild tremors or have difficulty getting out of a chair. They may notice that they speak too softly, or that their handwriting is slow and looks cramped or small. Friends or family members may be the first to notice changes in someone with early Parkinsons. They may see that the persons face lacks expression and animation, or that the person does not move an arm or leg normally.

People with Parkinson’s disease often develop a parkinsonian gait that includes a tendency to lean forward take small, quick steps and reduce swinging their arms. They also may have trouble initiating or continuing movement.

Symptoms often begin on one side of the body or even in one limb on one side of the body. As the disease progresses, it eventually affects both sides. However, the symptoms may still be more severe on one side than on the other.

Cbd Oil For Parkinsons

CBD oil can help with various health issues, significantly in pain and high blood pressure.

Preliminary research has found that CBD oil may help with treating quality-of-life issues in patients without psychotic symptoms. Another study showed the effectiveness of CBD in the treatment of psychosis in PD patients. The treatment did not worsen motor functions, and one of CBDs benefits was that it alleviated the psychotic symptoms present in PD patients.

There are clear advantages to using CBD oil for Parkinsons in the relief of non-movement-related symptoms, not to mention it may have neuroprotective effects as part of the treatment.

While few studies exist as to CBDs potential benefits on movement disorder treatment in PD, clinical and pre-clinical research has shown a reversal of catalepsy in rodent models. And, dose-related improvement in dystonia was noted with CBD oil in five patients in an open-label study on movement disorders.

The improvement ranged from 20% 50% in its effects on dystonia symptoms of Parkinsons. More research is needed on CBDs effects on the nervous system in general and on the motor and non-motor symptoms, specifically in people with Parkinsons.

While evidence exists as to the positive effects that CBD may have on PD patients quality of life issues, such is not the case for medical marijuana. There is insufficient evidence as of the last updated study in 2020 to indicate medical marijuanas usefulness to treat PD patients motor symptoms.

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Monoamine Oxidase Type B Inhibitors

MAO B inhibitors, such as Zelapar , Azilect , and Xadago , are typically considered for milder or less-advanced cases. Dosages vary based on type. For instance, 5 mg of Zelapar twice a day is currently the recommended indication.

Potential side effects of MAO B inhibitors are similar to other therapies and include headache, nausea, confusion, hallucinations, and dyskinesia.

Causes Of Parkinson’s Disease

Traveling the Rocky Treatment Path with Parkinsons Disease

The causes of Parkinsons disease are still greatly unknown. Scientists who have studied this disorder estimate that 10-15% of cases come from genetics after seeing a series of genetic mutations that were common in Parkinsons patients.

Doctors suspect that environmental factors and lifestyle choices may have effects on the severity of Parkinsons disease symptoms. Exposure to chemicals like pesticides may increase the likelihood of developing Parkinsons disease. On the other hand, a good diet and regular exercise may decrease your chances.

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Medication For Parkinsons Disease

Once the doctor diagnoses Parkinsons disease, the next decision is whether a patient should receive medication, which depends on the following:

  • The degree of functional impairment

  • The degree of cognitive impairment

  • Ability to tolerate antiparkinsonian medication

  • The advice of the attending doctor

No two patients react the same way to a given drug, therefore, it takes time and patience to find an appropriate medication and dosage to alleviate symptoms.

How To Administer Cbd Oil For Parkinsons Disease

Commercial CBD oil may come in 30 ml bottles with a 1 ml dropper in it. The 30 ml vial concentration will differ, so if you have a 500-milligram bottle, each 1 ml dropper will contain 50 milligrams in one dropper-full of CBD. The label should have a table of contents indicating the dose per bottle and dropper.

For the fastest absorption and effects of CBD, squeeze the oil onto the back of the underside of your tongue for rapid absorption through the blood vessel located directly under the tongue. Most CBD bypasses the gastrointestinal tract, and this increases the rate of absorption.

The fastest absorption method is achieved with the use of vape pens. You may experience effects within minutes of using a vape pen. CBDs effects are noted within minutes of vaping.

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Parkinsons Disease: Causes Symptoms And Treatments

Parkinsons disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination.

Symptoms usually begin gradually and worsen over time. As the disease progresses, people may have difficulty walking and talking. They may also have mental and behavioral changes, sleep problems, depression, memory difficulties, and fatigue.

While virtually anyone could be at risk for developing Parkinsons, some research studies suggest this disease affects more men than women. Its unclear why, but studies are underway to understand factors that may increase a persons risk. One clear risk is age: Although most people with Parkinsons first develop the disease after age 60, about 5% to 10% experience onset before the age of 50. Early-onset forms of Parkinsons are often, but not always, inherited, and some forms have been linked to specific gene mutations.

What Are Surgery Options For Parkinson’s Disease

Parkinson’s Disease (Shaking Palsy) – Clinical Presentation and Pathophysiology

Depending upon your needs, medical history, health, and symptoms, one of the following procedures may be considered for Parkinson’s disease:

There are many other procedures being researched. One of the most promising involves the transplantation of fetal dopamine neurons into the brains of people with Parkinson’s disease. The hope is that these cells will be able to re-grow the damaged dopamine-producing nerve cells.

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What Parkinsons Disease Treatment Options Are Right For You

All of the above Parkinsons disease treatment options should be discussed with your doctor before implementation. Most of the treatments listed above your doctor will likely prescribe for you with exceptions for DBS, which will be prescribed for specific situations. Whatever Parkinsons treatment your doctor prescribes you it is important to take their advice and be consistent with your treatment plan.

Parkinsons symptoms can be managed and there is no reason you cant live a normal and fulfilling life if you stick to your Parkinsons disease treatment plan prescribed by your doctor.

Support For People Living With Parkinsons Disease

While the progression of Parkinsons is usually slow, eventually a persons daily routines may be affected. Activities such as working, taking care of a home, and participating in social activities with friends may become challenging. Experiencing these changes can be difficult, but support groups can help people cope. These groups can provide information, advice, and connections to resources for those living with Parkinsons disease, their families, and caregivers. The organizations listed below can help people find local support groups and other resources in their communities.

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Medications For People With Parkinsons Disease

Symptoms of Parkinsons disease result from the progressive degeneration of nerve cells in the brain and other organs such as the gut, which produce a neurotransmitter called dopamine. This causes a deficiency in the availability of dopamine, which is necessary for smooth and controlled movements.

Medication therapy focuses on maximising the availability of dopamine in the brain. Medication regimes are individually tailored to your specific need. Parkinsons medications fit into one of the following broad categories:

  • levodopa dopamine replacement therapy
  • dopamine agonists mimic the action of dopamine
  • COMT inhibitors used along with levodopa. This medication blocks an enzyme known as COMT to prevent levodopa breaking down in the intestine, allowing more of it to reach the brain
  • anticholinergics block the effect of another brain chemical to rebalance its levels with dopamine
  • amantadine has anticholinergic properties and improves dopamine transmission
  • MAO type B inhibitors prevent the metabolism of dopamine within the brain.

There is no best medication treatment for Parkinsons. Each person has different symptoms, disease progression, lifestyle and physical tolerances. All of these factors will affect the timing, type, dose and combinations of medication.

As the disease progresses, your doctor will need to review and alter your medication program. Its is important to see a neurologist or a doctor who has experience in helping people with Parkinsons disease.

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