Wednesday, April 10, 2024
Wednesday, April 10, 2024
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Cutting Edge Parkinson’s Treatment

Should I Talk To My Healthcare Provider Before I Start Exercising If I Have Parksinson’s Disease

New technology could signal the future of medicine

Talk to your neurologist and your primary care provider before starting a new exercise regimen. They can:

  • Counsel you on how intense your exercises can be.
  • Recommend exercises appropriate for your individual health.
  • Refer you to a physical therapist to create a personal exercise program.
  • Warn about exercises to avoid based on your particular challenges or limitations.

Clinical Trials Of Parkinsons Therapies Robust Despite Covid

With funding from APDA, these researchers can further develop their theories and obtain significant pilot data and initial proof of concept that enables them to apply for and receive larger grants from the National Institutes of Health and other funding institutions, Gilbert said. Without this initial funding from APDA, some research projects might never get off the ground.

Since its foundation, in 1961, APDA has raised and invested more than $207 million to provide outstanding patient services and educational programs, raise public awareness about Parkinsons, and support cutting-edge research meant to ultimately end the disease.

This years APDAs awards include a George C. Cotzias fellowship , two Diversity in Parkinsons Disease Research grants, three post-doctoral fellowships, six research grants, and continued funding for eight APDA Centers for Advanced Research.

The three-year George C. Cotzias fellowship is awarded to a young physician-scientist with exceptional promise to fund an innovative long-range project. This years winner is Abby L. Olsen, MD, PhD, at the Brigham and Womens Hospital, who will focus on the therapeutic potential of glia, which are non-neuronal cells that play critical roles in brain function, in Parkinsons.

The post-doctoral fellowships are designed to support early career post-doctoral scientists whose promising research focuses on Parkinsons causes, effects on the body, and treatments.

New Treatment For Tremors: Cutting

Oregon Health & Science University is now the first in Oregon to offer a cutting-edge type of brain surgery that doesnt involve cutting at all.

The procedure, known as focused ultrasound, directs more than 1,000 sonic beams through the skull to create a small lesion in the focal point of the brain that causes a condition known as essential tremor. Approved by the Food and Drug Administration for clinical use in 2016, the procedure also treats a related condition known as tremor-dominant Parkinsons disease.

The OHSU neurosurgeon leading the new program expects a surge of interest among patients with tremors across the Pacific Northwest.

Patients love it, and the results are instantaneous, said Ahmad M. Raslan, M.D., FAANS, associate professor of neurological surgery in the OHSU School of Medicine.

Thats certainly the case for Raslans first focused ultrasound patient, 73-year-old Madras, Oregon, resident Jean Henderson.

For the past three years, the uncontrollable tremor in her hands meant that she couldnt so much as sign her name or drink a cup of coffee without spilling it.

I try to eat and I really cant, she said. Sometimes, I have to just use my fingers to put food in my mouth. Its really hard.

All that changed in an instant on March 30, when Henderson made history as the first person in Oregon to undergo the procedure.

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Are There Any Risks Of Exercising With Parkinsons Disease

Some symptoms, like Parkinsons tremors, may seem worse during exercise. But exercise generally improves tremors and other symptoms in the long run.

Reduce challenges by stretching before and after exercise. Use good form to prevent injury. And avoid slippery floors, poor lighting and tripping hazards. If you have pain, stop and rest.

Pushing yourself too hard during exercise can lead to injury. Start slowly and increase intensity and duration over time. Keep a log to track your exercise choices and how you feel. Eventually, youll learn what works best for you.

Deep Brain Stimulation Has Been Around For Two Decades But Now It Can Be Managed By The Touch Of An Ipod

Is There Any Cure For Parkinson

The tremors started when Paul Detlefsen was in his 30s. At 36, he got the diagnosis: Parkinsons disease.

It was tough news for the Woodbridge resident, who works with his hands as a machine mechanic.

I had real bad tremors in my right arm, he said. I didnt want to leave the house. I kind of got depressed.

Three years ago he opted to treat the symptom with deep brain stimulation , which uses surgically implanted electrodes to stimulate areas of the brain that control movement. DBS therapy, which has been around for two decades, had the desired effect.

Now you couldnt even tell I have Parkinsons, the 43-year-old said.

The only real drawback was the remote control unit that came with the DBS system. If the units settings had to be changed because tremors returned, it required an appointment with a specialist. There were other inconveniences as well.

It was bulky and you had to check the battery, Detlefsen said. To look at it, you had to take it off and youd lose contact.

Thats all changed with the rollout of technology that allows the patient to manage their DBS with the touch of an iPod. JFK Neuroscience Institute in Edison is at the forefront of using the iPod. In fact, Detlefsen is the first patient in the United States and among the first in the world to marry the traditional DBS system with this iPod touch remote.

Staff writer Jerry Carino: .

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Uncovering The Brain Circuitry Changes In Parkinsons Disease

Two National Institutes of Health funded studies led by Un Jung Kang, MD, the Founders Professor of Neurology, professor in the Department of Neuroscience and Physiology, and director of translational research in the Department of Neurology and Fresco Institute for Parkinsons and Movement Disorders, seek to reveal the dynamic between therapeutic dopaminethe standard of care for patients with the conditionand the brain circuitry behind motor dysfunction.

In the first study, Dr. Kang is mapping cell types in the brains striatum to investigate how this circuitry influences so-called motor learning, which may underlie the long-duration therapeutic response seen in dopamine-treated patients. Were discovering that dopamine not only helps patients move better, but also contributes to sustained functional improvement, he says. Were trying to understand whats behind this gradual buildup of benefit and how long it lasts.

Paradoxically, Dr. Kang and his team are also investigating how brain compensation can interfere with dopamines therapeutic effects. When treatment begins, some patients brain circuitry, having rewired itself to adapt to dopamine loss, leads to hypersensitive response. They go from movements that are too slow to uncontrolled movements that interfere with mobility for the opposite reason, notes Dr. Kang. The rewired brain no longer knows what to do with the dopamine.

Supporting Patients And Their Families

Our expert team of medical professionals have decades of experience working with patients suffering from all types of movement disorders, and we remain committed to keeping up to date with the most cutting edge treatment options. Chronic neurologic disorders like Parkinsons disease can be incredibly difficult to manage for patients, as well as their families and loved ones. Contact us today to learn more about what services we offer to help you receive the support and care you need.

Patient Stories

  • It was like turning on a light switch. Literally the next day, my voice was almost back to normal.

    Mike

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What Will A Cure For Parkinson’s Look Like

Parkinson’s varies so much from person to person. There are over 40 symptoms of Parkinsons. Tremor. Pain. Hallucinations. Everyones experience is different.

Because of this, there may not be a single ‘cure’.

Instead, we may need a range of different therapies to meet the needs of the individual and their specific form of the condition.

This mix may include treatments, therapies and strategies that can:

  • slow or stop the progression of the condition
  • replace or repair lost or damaged brain cells
  • control and manage particular symptoms
  • diagnose Parkinson’s at the earliest possible stage.

And this could involve medical treatments, such as drugs and surgical approaches, as well as lifestyle changes, for example to diet and exercise.

Restoring The Quality Of Life You Deserveinova Parkinson’s And Movement Disorders Center

A cure for Parkinson’s: Overcoming the blood brain barrier

Be it Parkinson’s disease, essential tremor, dystonia or other movement disorders, the Inova Parkinson’s and Movement Disorders Center provides comprehensive care designed to get you moving again.

From the first moments you meet with one of our specialists, you will understand our team’s dedication to individualized care. Each person has his or her own unique brand of Parkinson’s, essential tremor, dystonia, Huntington’s disease or tic disorder and deserves a personalized treatment plan to address specific needs. Our experienced movement disorders team will work with you to chart a path to better health.

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Multidisciplinary Movement Disorders Clinic

Patients who come to the Movement Disorders Clinic are seen by a movement disorders specialist, a neurologist who has extra training in evaluating and treating a person with Parkinsons disease. There are no blood or imaging tests that can confirm Parkinsons disease, so diagnosis is based on visible signs and symptoms, which are reviewed during a medical history and neurologic examination.

Why Choose Hackensack Meridian Health For Your Care

Excellence

Jersey Shore University Medical Center has earned the Healthgrades Neurosciences Excellence Award in 2020, 2021 and 2022.

Quality

Hackensack University Medical Center is recognized by The Joint Commission, a national health care accreditation organization, for excellence in care and treatment for Parkinsons Disease care, we offer the regions most complete lineup of neuroscience services for movement disorders.

Innovation

Hackensack Meridian Healths Neuroscience Institute is a leader in the diagnosis and treatment of brain and spine disorders and for our cutting-edge research to advance the treatment of traumatic brain injury and stroke.

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Vibrating Socks To Reduce Freezing Gait

This innovative accessory being developed by researchers in the Netherlands is designed to act as a cue for reducing freezing of gait a Parkinsons symptom that is sometimes described as the feeling that your feet are glued to the ground.

Many existing cueing systems, such as using marks on the floor or an audible metronome, can be visible to others which is often off-putting for people with the condition. The team hope that these vibrating socks could be an alternative way of supporting mobility and improve the quality of life of people with the condition.

If I Exercise Will I Still Need My Parkinsons Medications

Groundbreaking Implant Can REVERSE Parkinson

Some people find that exercise helps them reduce the doses of Parkinsons medications over time. But exercise is not a replacement for your medications. In fact, some people need more medications so they can stay active. Dont make changes to your medications without talking to your healthcare providers.

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Specialized Neurology And Neurosurgery Services In At Bwh

Parkinson’s disease diagnosis and treatment are administered by the Department of Neurology at BWH, which integrates a diverse array of specialized services for patients with neurological disorders. The BWH Boston neurology campus partners with our community locations at Brigham and Women’s Faulkner Hospital in Jamaica Plain and with Brigham and Women’s/Mass General Health Care Center in Foxborough and South Shore Hospital in Weymouth to offer state-of-the-art facilities and the largest neuroscience intensive care unit in the New England region.

Neurosurgical treatment for Parkinson’s disease is provided by specialists in our world-class BWH Department of Neurosurgery. Our expert Boston neurosurgeons deliver comprehensive neurosurgery treatment through many innovative techniques to improve outcomes for our neurosurgery patients. The Department’s Boston neurosurgery staff of more than 13 clinical faculty and over 100 department members strives to provide patient-focused, world-class medical treatment across the spectrum of neurological diseases, including Parkinson’s disease.

Identifying And Treating Parkinson’s Disease

Mercy Health Hauenstein Neurosciences specializes in the diagnosis and treatment of Parkinson’s disease. We believe in addressing the body not as a home for symptoms, but as a combination of many complex systems, each with different needs.

For over a decade, we’ve treated Parkinson’s disease through an interdisciplinary approach, cutting-edge technology, partnerships with organizations such as Van Andel Research Institute and Michigan State University, and more.

Parkinsons disease affects each patient differently. We place the patient in the center of a team of providers who work together to address the physical, mental and spiritual needs of patients and their families.

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Parkinsons: Foundation: Centers: Of: Excellence

Together with you and your family, ColumbiaDoctors Neurology Movement Disorders specialists will work to build a complete picture of your disorder, and help you to understand and manage your treatment options. We pride ourselves on providing expert, compassionate care, and diagnostic testing for a wide range of movement disorders, including:

  • Atypical Parkinsonisms/ Parkinson-plus syndromes: progressive supranuclear palsy , multiple system atrophy , Olivopontocerebellar atrophy , Shy-Drager syndrome, corticobasal syndrome
  • Chorea including Huntingtons disease, Sydenhams chorea
  • Dystonia including blepharospasm, torticollis, writers cramp, and musicians cramp
  • Essential Tremor and other tremor disorders
  • Hemifacial spasm
  • Tourette syndrome, tics
  • Wilsons disease

ColumbiaDoctors Neurology Movement Disorders Practice also has several highly-trained neurological specialists who perform special procedures for the treatment of movement disorders, including:

  • Botulinum toxin injection
  • Deep brain stimulation

Parkinsons Foundations National Medical Director, Dr. Michael S. Okun, and infectious disease expert, Dr. Frederick S. Southwick, both of the University of Florida, answer YOUR questions about the disease as it relates to Parkinsons disease, and discuss the precautions you and your loved ones should take to stay healthy.

Why Choose Uhealth

Deep-Brain Stimulation Surgery Provides Life-Changing Results for Parkinsons Patient

One of only 47 Centers of Excellence designated by the Parkinsons Foundation.When you are seen by our team of experts, you are receiving treatment from leaders in Parkinsons care. Our neurologists are considered experts by their peers and have special training in movement disorders and PD.

Treatment tailored specifically to you. Our health care professionals will help you develop and follow a healthy eating plan and remain or get physically active. You may need insulin if your nutrition plan and physical activity fail to keep your blood glucose in your target range.Personalized care in one location. Every person who has Parkinsons disease is different. Once diagnosed, your neurologist will discuss a treatment plan with you that is aimed at minimizing your symptoms. Our team includes neurologists, physical therapists, and other professionals who work together to decrease the symptoms and increase your quality of life.

Holistic, intersectional support: In addition to standard treatments and exclusive clinical trials, our one-of- a-kind program provides our UHealth PD patients and their families with:

  • Monthly support groups
  • Post-surgery Deep Brain Stimulation support groups
  • Social worker services
  • Multiple educational symposiums, conferences and events on PD

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How Does It Work

The treatment will involve stem cells that can be transformed into dopamine, a chemical lost in Parkinsons that plays a crucial role in helping people to move.

To circumvent some of the usual challenges associated with sourcing stem cells, including practical issues related to supply, the researchers have developed technology enabling the cells to be grown in lab cultures. They are said to have been created under good manufacturing practice at the Royal Free Hospital in London, UK.

Furthermore, the researchers have been able to programme these cells to develop into dopamine nerve cells that will be transplanted into the brains of those living with the condition.

We now know that putting dopamine cells in the brain will work and the procedure is safe. There is no longer a problem about supply of sufficient tissue because we can manufacture these cells in large numbers in the laboratory, said Professor Barker.

That means that we are now at a point where we can use stem cell transplants as treatments for Parkinsons patients, though it will take several years before we will know that these work and can be used as standard treatments for Parkinsons disease.

For more information on the latest Parkinsons research, please visit the Parkinsons Europe website.

Read more:

Muhammad Ali Parkinson Center: A Hub For Cutting

More than two decades since its establishment in 1997 and five years following famed boxer Muhammad Alis passing, the Muhammad Ali Parkinson Center remains committed to upholding the mission of fighting for a cure for this condition through groundbreaking research and top-notch patient care.

The renowned movement disorder center has held steadfast to the wishes of Lonnie and Muhammad Ali that all patients and caregivers have access to the same level of outstanding services that Ali received throughout his battle with the neurodegenerative disease.

This dream of Lonnie and Muhammads is what drives many of our goals at the Center, said Holly Shill, MD, movement disorder neurologist and director of the Muhammad Ali Parkinson Center at Barrow Neurological Institute at Dignity Health St. Josephs Hospital and Medical Center in Phoenix. We are thrilled to be able to offer our patients access to the types of research studies that could really be game changers in the way we understand and treat the disease.

We are also proud to be involved in the second phase of a landmark clinical study by the Michael J. Fox Foundation called the Parkinsons Progression Markers Initiative . The main goal of this initiative is to better understand Parkinsons onset and progression in order to expedite the development of new treatments, which are incredibly important for neurologists to have in our tool kits, said Dr. Shill.

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Parkinsons Foundation Center Of Excellence

The Department of Neurology at UNC has been actively caring for patients with Parkinsons disease since the opening of the North Carolina Memorial Hospital in 1952. In 2004, the UNC School of Medicine and UNC Hospitals became the first medical center in North Carolina to join the ranks of only 47 Parkinsons Foundation Centers of Excellence worldwide.

The Parkinsons Foundation supports Parkinsons-related research, patient care, education, training, and outreach through its centers of excellence. As such, the centers define the gold standard in Parkinsons-related research, comprehensive care and outreach. Learn more about the Parkinsons Foundation and the Parkinsons Foundation Center of Excellence criteria.

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