Wednesday, November 30, 2022
Wednesday, November 30, 2022
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How Is Treatment Used To Determine Parkinson’s Disease



As The Second Most Common Neurodegenerative Disease Parkinsons Disease Is An Important Subject Of Ongoing Research And Innovation

Drugs Used for Treatment Parkinson Disease

However, it also presents unique challenges as the pathophysiology behind the disease remains complex and often medication is not effective for all patients. Additionally, clinical rating scales are limited in their ability to provide quantitative data for researchers. When conducting clinical trials, patients suffering from PD are often limited in their ability to travel to sites, and as a result, this burden can be a barrier to participation. In regard to these concerns, recent advances in medical devices and digital health technologies, such as wearables and apps, may offer new solutions for physicians and researchers, and determine the direction of treatment in the future.

Research On Medical Marijuana In The Treatment Of Multiple Sclerosis And Parkinsons Disease

In spite of the vast anecdotal, lab, and clinical evidence surrounding the efficacy of medical marijuana for treatment of Parkinson’s and multiple neurological disorders, considerable controversy still exists.

However, some reputable medical journals have published the following reports:

  • Researchers from London’s Institute of Neurology reported: “In addition to symptom management, cannabis may also slow down the neurodegenerative processes that ultimately lead to chronic disability in multiple sclerosis and probably other neurodegenerative diseases.”
  • Dr. Andras Bilkey-Gorzo reported in a 2012 research review: “At first sight, it is striking that cannabinoid, substances known to impair cognitive functions, could be beneficial in neurodegenerative cognitive disorders. However, cannabinoid receptor activation could reduce oxidative stress and excitotoxicity, suppress neuroinflammatory processes, and thus alleviate the symptoms of neurodegenerative motor and cognitive diseases.”

Pharma Company Also Plans To Investigate Psychedelic Therapies For Multiple Sclerosis

In 2006, Johns Hopkins researchers published a groundbreaking study on the effects of a single dose of psilocybin, a naturally occurring psychedelic compound found in more than 200 species of mushrooms. The team had to set up “unusually rigorous scientific conditions and measures” amid highly restrictive regulatory policies, which were partially due to unfavorable media coverage from the recreational use of “shrooms” in the 1960s and ‘70s that had resulted in misperceptions of risk.

The landmark study provided a scientific framework to better understand how hallucinogenic drugs target the brain’s serotonin receptors, and the researchers announced future plans to investigate how psilocybin might be used to treat conditions like cancer-related anxiety and depression, and other mental health conditions. Since then, more than 60 peer-reviewed articles in scientific journals further validated the safety and enduring positive effects of a unique class of pharmacological compounds known as psychedelics.

The US Food and Drug Administration has since granted breakthrough therapy designation for psilocybin to determine its viability for treating major depressive disorder, opening enrollment to patients for clinical studies in 2019. 

in Neuropsychiatric Disorders Laboratory is studying why people with mental illnesses have trouble with social connection. 

For Weisblum, working in this industry has been particularly personal.

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Natural Remedies And Treatments For Parkinsons Disease That Get Powerful Results

To successfully treat the symptoms of Parkinson’s, andeven reverse this disorder, there are 4 things you must do…

a)  Increase your natural dopamine levels 

b)  Detox your body of all heavy metals andpollutants 

c)  Reduce all inflammation in the body,especially the brain

d) Repair the neuro pathways 

These 10 natural treatments and remedies do all four. Solet’s not waste any more time then. Here they are in order of importance…

Transcranial Direct Current Stimulation For The Treatment Of Parkinsons Disease

Parkinson

Objective/Rationale:Current treatments for Parkinson’s disease are either associated with side effects, expensive, or their efficacy diminishes over time. Thus, the development of practical, inexpensive and effective long-term, adjunct treatments is needed in PD research. Transcranial direct current stimulation may represent one such intervention with a realistic potential to be translated into clinical practice. The goal of this project is to identify the optimal stimulation parameters for the application of tDCS to improve motor and cortical function in PD.

Project Description:The project comprises two studies designed to examine the efficacy of different tDCS protocols of improving motor function in PD. The first study will determine the optimal timing of tDCS relative to practice of a motor task to improve motor performance, whereas the second study will examine the optimal intensity of tDCS to improve motor performance. The studies will also determine if motor performance improvements attained in a task practiced in association with tDCS can be generalized to non-trained tasks such as a common clinical measure of motor function and various functional manual dexterity tests. Additionally, transcranial magnetic stimulation will be performed before and after the tDCS interventions to assess selected cortical pathways that are commonly impaired in PD and determine the extent to which tDCS impacts these pathways.

Naturaltreatment For Parkinsons #9 Exercise And Other Alternative Therapies:

Regular exercise has been shown to help Parkinson’ssufferers by reducing muscle stiffness, increasing mobility, and enhancing postureand balance. Exercise also increases oxygen levels and neurotransmitters, alongwith releasing potent “mood elevating” chemicals called endorphins.

The type of exercise performed for PD is crucial. Aqua orwater aerobics can be particularly useful as traditional exercise is usuallyquite difficult for many Parkinson’s sufferers. Muscle decline, loss of strength,stiffness and loss of balance can make conventional exercises difficult toperform. The great thing about aqua aerobics is it still has the same benefits as other exercise regimens,but the risk of falling is eliminated.

Other types of exercises that can be beneficial for PDsufferers include Tai Chi, Yoga, dancing, walking, aerobic/jazzercise classes,and general stretching.

For more information on the different exercise programsavailable for Parkinson’s patients, you can check out this website…  Exercise and Physical Therapy for Parkinson’sDisease

Natural Treatment For Parkinsons #3 Turmeric And Otherherbs And Spices:

A recent study published in the journal Stem Cell Research & Therapy, foundthat the extracts in turmeric, particularly curcumin and the newly discovered Ar-turmerone,can regenerate “a damaged brain” and reverse neurological disorders.  Researchers said Ar-turmerone is “a promising candidate to supportregeneration in neurologic disease.” Michigan State University researcherBasir Ahmad also found that a compound in turmeric may help fight Parkinson’sdisease by disrupting the proteins responsible for the disease.

Another study published in the Pharmacognosy Magazine found that tumeric can prevent and evenreverse the toxic effects exerted on the brain from fluoride exposure. Fluorideis a nasty and dangerous heavy metal that destroys brain cells and the intricateworkings of the central nervous system. Fluoride poisoning has also beenimplicated in the development of neurological diseases such as Alzheimer’s,Parkinson’s, ALS and multiple sclerosis. 7

Turmeric is also a very potent anti-inflammatory spice. Because Parkinson’s is aninflammation type disease, turmeric will help immensely. A heaped teaspoon ofhigh quality turmeric powder taken 3 times daily in asmoothie will do the trick. Just make sure you combine it with 10-12 blackpeppercorns for enhanced absorption Turmeric is also fat soluble so you’ll need tocombine it with some coconut oil, red palm oil or fish/krill oil as well.

What Is Essential Tremor And How Is It Different To A Parkinsons Tremor

A tremor is a rhythmical, involuntary movement that affects a part of the body, such as the hand.

Essential tremor is the most common type of tremor. It’s most noticeable when your hands are doing something and it usually affects both the right and left sides of the body equally. Essential tremors often lessen when your body is resting. 

Unlike an essential tremor, a Parkinson’s tremor is most obvious when the affected body part is resting and tends to be less noticeable with movement. It usually starts on one side of the body and may progress to the other side as Parkinson’s develops.

The time it takes to get a diagnosis can vary from person to person. Some people may receive a diagnosis of Parkinson’s quite quickly, but for others it may be a long process. This can be due to a number of things, including your medical history, your age and what symptoms you have.

Your specialist may wish to rule out other causes of your symptoms first and see how you respond to treatment. This may take some time, and, as already mentioned, there is currently no definitive test for Parkinson’s.

How you respond to treatment may help your specialist make a diagnosis. Keeping a diary or record of your symptoms will give the specialist more information to guide their decision.

Because the symptoms of Parkinson’s are sometimes similar to other forms of parkinsonism, people can sometimes be misdiagnosed. 

Parkinsons Foundation Centers Of Excellence And Medicinal Marijuana

Which Medications are Available for Parkinson Disease ...

The Parkinson’s Foundation, in partnership with Northwestern University researchers, studied attitudes about cannabis at 40 Centers of Excellence. To the best of our knowledge, this is the first study to provide data on the practices, beliefs and attitudes of expert PD physicians concerning cannabis use.  

The results were interesting: most experts said they knew what cannabis did, but disagreed on the details. While there is no general agreement on what the benefits might be for people with PD, the survey confirmed that cannabis is a popular subject within Parkinson’s Foundation centers as 95 percent of neurologists reported patients have asked them to prescribe it.

Cannabis study results also included:

  • Only 23 percent of physicians had any formal education on the subject of cannabis , thus 93 percent of physicians want cannabis taught in medical school.
  • Physicians reported that 80 percent of their patients with PD have used cannabis.
  • Only 10 percent of physicians have recommended the use of cannabis to patients with PD.
  • In terms of memory: 75 percent of physicians felt that cannabis would have negative effects on short-term memory and 55 percent felt that cannabis could have negative effects on long-term memory
  • Only 11 percent of physicians have recommended use of cannabis in the last year

This graph shows how physicians expect cannabis would improve, worsen, or show no effect to PD-related symptoms given their expertise and observations of patients with PD.

Determining Diagnosis Through Response To Parkinsons Medication

If a person’s symptoms and neurologic examination are only suggestive of Parkinson’s disease or if the diagnosis is otherwise in doubt, the physician may, nevertheless, prescribe a medication intended for Parkinson’s disease to provide additional information. In the case of idiopathic Parkinson’s, there is typically a positive, predictable response to Parkinson’s disease medication; in the case of some related Parkinsonian syndromes, the response to medication may not be particularly robust, or it may be absent entirely.

Unfortunately, there are no standard biological tests for the disease, such as a blood test. However, researchers are actively trying to find biomarkers in blood and other bodily fluids that could help confirm the diagnosis.

Natural Treatment For Parkinsons #1 Cannabis/medicalmarijuana:

Cannabis, aka medical marijuana, is an incredibletreatment for Parkinson’s disease. You can have a Parkinson’s patient shakingviolently and uncontrollably, and yet within 30-40 minutes of self-administering with some cannabis, their symptoms will almost completely disappear. Watch this short 2minute video from Parkinson’s sufferer, Ian Frizell, who shows you what he waslike before self-medicating with cannabis and then again after. The change is truly astonishing! 

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Taylor French is another Parkinson’s patient thatundergoes a remarkable transformation once he ingests what he calls “nutritional vegetable extract” . This guy has an advanced form ofParkinson’s and is normally confined to a wheelchair with limited use of hisbody due to stiff and rigid muscles . But after ingestingsome cannabis he’s able to walk, and incredibly, in his video he even getsinto his car and drives off down the road!

You can view it here…

Elyse Del Francia also tells the story of her Parkinson’ssuffering husband, and the time she decided to smother his morning pancakes withsome canabutter. She said…

“Within45 minutes of eating a pancake with marijuana on it, he stopped shaking. Thatwas my lightbulb moment. That’s when I knew that I was onto something thatwould relieve his pain and suffering, because it’s horrible, horrible, to haveParkinson’s Disease and not have any relief. I feel that this is something thathelps so many people in so many ways with pain and suffering.” 5

What Lifestyle Changes Can I Make To Ease Parkinsons Symptoms

Exercise: Exercise helps improve muscle strength, balance, coordination, flexibility, and tremor. It is also strongly believed to improve memory, thinking and reduce the risk of falls and decrease anxiety and depression. One study in persons with Parkinson’s disease showed that 2.5 hours of exercise per week resulted in improved ability to move and a slower decline in quality of life compared to those who didn’t exercise or didn’t start until later in the course of their disease. Some exercises to consider include strengthening or resistance training, stretching exercises or aerobics . All types of exercise are helpful.

Eat a healthy, balanced diet: This is not only good for your general health but can ease some of the non-movement related symptoms of Parkinson’s, such as constipation. Eating foods high in fiber in particular can relieve constipation. The Mediterranean diet is one example of a healthy diet.

Preventing falls and maintaining balance: Falls are a frequent complication of Parkinson’s. While you can do many things to reduce your risk of falling, the two most important are: 1) to work with your doctor to ensure that your treatments — whether medicines or deep brain stimulation — are optimal; and 2) to consult with a physical therapist who can assess your walking and balance. The physical therapist is the expert when it comes to recommending assistive devices or exercise to improve safety and preventing falls.

Improve the quality of your sleep.

Brain Imaging And Other Tools To Aid Diagnosis Of Parkinsons

Medications for the Treatment of Parkinson

In addition to taking a history and performing a detailed neurologic examination, physicians sometimes use brain imaging to help support a particular diagnosis. However, these studies have their limitations in the diagnosis of Parkinson’s disease and are typically used only in select patients. Brain imaging is not routinely performed by neurologists or movement disorder specialists when they are considering a diagnosis, especially if the person’s symptoms strongly suggest to the physician that idiopathic Parkinson’s disease is the correct diagnosis.

Helping diagnose Parkinson’s with DaTscan and other tests

Rather, use of imaging is most helpful when the diagnosis is uncertain, or when physicians are looking for changes in the brain that are more typical of one of several Parkinsonian syndromes and other conditions that can mimic Parkinson’s. Imaging studies to evaluate Parkinson’s disease and Parkinsonian syndromes include magnetic resonance imaging , which examines the structure of the brain, and DaTscan, an imaging test approved by the Food and Drug Administration to detect the dopamine function in the brain. A DaTscan may help differentiate idiopathic Parkinson’s disease from certain other neurologic disorders. Most physicians’ offices will have access to MRI; however, DaTscan imaging may only be available at larger hospitals or medical centers.

Low Intensity Focused Ultrasound To Help Deliver Therapies

While high intensity FUS is a treatment for PD as described above, low intensity FUS can be used in an entirely different way to help treat PD. This type of FUS may allow for disruption of the blood brain barrier. The blood brain barrier refers to the cells that line the blood vessels within the brain which keep foreign substances, such as toxins and microbes, in the bloodstream and out of the brain.

Normally, this mechanism is advantageous and protects the brain. However, the blood brain barrier may also keep out molecules that could help to treat brain diseases. Therefore, disrupting the blood brain barrier could allow for penetration of these molecules into particular areas of the brain. A whole variety of different molecules such as antibodies, nerve growth factors and gene therapy may be able to take advantage of this approach. Further research is necessary to determine if this will be a useful method for drug delivery into the brain.

Natural Remedies And Treatments For Parkinsons Finalnote

So there you have our top 10 natural remedies andtreatments for reversing Parkinson’s disease. We believe this is one of the most informative andthorough health articles on this disease you’ll find anywhere on the internet. Ifyou follow these 10 tips to-the-letter and continue to use them consistently,we guarantee that in 3-6 months’ time you will be truly astounded at themiraculous level of improvement you’ll see. In 12 months’ time you will scarcely recognize yourself! . But of course, you must stickwith them and follow through with each remedy every day if you want them towork. We sincerely hope you do.

Good luck and best wishes.

P.S. Because Parkinson’s is closely linked to Alzheimer’s disease and actually goes under the “dementia umbrella”, we recommend you take the time to read our “Powerful Natural Remedies for Dementia and Alzheimer’s” article for a more complete and comprehensive understanding on the causes and treatments for these diseases. You can click on the link below to go there…

Contact Our New Patient Coordinator For More Information

When many patients come to see us, they have lost hope as they don’t see any light at the end of the tunnel. It’s rewarding as a practitioner to be able to help so many people realize a much better “normal” and a greatly improved quality of life.

If you have questions or would like to discuss our Treatment Protocols, we offer a Free consultation by phone. Our New Patient Coordinator will take the time to listen and explain. She is able to answer most questions and discuss our protocols, scheduling, fees, and other information. She is happy to assist you in any way she can.

Please call us to get more information about how our clinic and Dr. Miller may be able to help you with your health goals and to schedule an initial screening to see if MeRT may be an option.

What Are The Surgical Treatments For Parkinsons Disease

Stem Cells Therapy: Stem Cells Therapy for Parkinson

Most patients with Parkinson’s disease can maintain a good quality of life with medications. However, as the disease worsens, medications may no longer be effective in some patients. In these patients, the effectiveness of medications becomes unpredictable – reducing symptoms during “on” periods and no longer controlling symptoms during “off” periods, which usually occur when the medication is wearing off and just before the next dose is to be taken. Sometimes these variations can be managed with changes in medications. However, sometimes they can’t. Based on the type and severity of your symptoms, the failure of adjustments in your medications, the decline in your quality of life and your overall health, your doctor may discuss some of the available surgical options.

What Is The Outlook For Persons With Parkinsons Disease

Although there is no cure or absolute evidence of ways to prevent Parkinson’s disease, scientists are working hard to learn more about the disease and find innovative ways to better manage it, prevent it from progressing and ultimately curing it.

Currently, you and your healthcare team’s efforts are focused on medical management of your symptoms along with general health and lifestyle improvement recommendations . By identifying individual symptoms and adjusting the course of action based on changes in symptoms, most people with Parkinson’s disease can live fulfilling lives.

The future is hopeful. Some of the research underway includes:

  • Using stem cells to produce new neurons, which would produce dopamine.
  • Producing a dopamine-producing enzyme that is delivered to a gene in the brain that controls movement.
  • Using a naturally occurring human protein – glial cell-line derived neurotrophic factor, GDNF – to protect dopamine-releasing nerve cells.

Many other investigations are underway too. Much has been learned, much progress has been made and additional discoveries are likely to come.

How Is Treatment Used To Determine Parkinson’s Disease useddisordersParkinson’s disease

Levodopa is the most commonly prescribed medicine for Parkinson’s. It’s also the best at controlling the symptoms of the condition, particularly slow movements and stiff, rigid body parts. Levodopa works when your brain cells change it into dopamine.

Additionally, how does Parkinson’s disease start? Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement. In the early stages of Parkinson’s disease, your face may show little or no expression. Your arms may not swing when you walk.

Also, what are the symptoms of Parkinson’s and how is it diagnosed?

These are the symptoms most often noticed by patients or their families: Shaking or tremor: Called resting tremor, a trembling of a hand or foot that happens when the patient is at rest and typically stops when he or she is active or moving. Bradykinesia: Slowness of movement in the limbs, face, walking or overall body.

What vitamin is good for Parkinson’s disease?

Dietary Supplements for Parkinson’s Disease

  • Coenzyme Q10. Coenzyme Q10 is an antioxidant that helps the cells obtain energy from oxygen.
  • Creatine.
  • Vitamin C and Vitamin E.
  • Glutathione.

Naturaltreatment For Parkinsons #6 Magnesium & Iodine:

Magnesium is vital for the health of the entire nervoussystem, especially the protective layer that surrounds the nerves . Magnesiumis also essential for the production of dopamine and helps protect dopaminergicneurons in the substantia nigra from degeneration. In addition to this, new evidence is showing that low levels of magnesium in the brain causes a build-up ofheavy metals – a major factor in the development of Parkinson’s, Alzheimer’s,epilepsy and MS. In a recent trial, 30 epileptics were given 450 mg ofmagnesium daily and this successfully controlled their seizures. Ifmagnesium can help epilepsy patients, it can certainly help Parkinson’s sufferers. Worldrenowned magnesium expert and author, Dr Carolyn Dean, has both Parkinson’s andAlzheimer’s disease in her “top 55 health conditions caused by amagnesium deficiency” list and says that magnesium is 100% essential for the preventionand treatment of both of these diseases… Dr Carolyn Dean Interview

In regards to iodine, well-known researcher and author,Dr James Howenstein, says…

“Iodineis found in large quantities in the brain and the ciliary body of the eye. A lackof iodine may be involved in the production of Parkinson’s disease andglaucoma.”

“Inthe brain, iodine concentrates in the substantia nigra, an area of the brainthat has been associated with Parkinson’s disease.”

David Brownstein M.D. 9

Best Sources of Magnesium and Iodine…

-What You’ll Need

1 cup of Magnesium Chloride Flakes

1 cup of Distilled Water

 

 

 

Best Marijuana Strains For Treating Parkinsons Disease

Novel Treatment Using Patient

Medical marijuana strains for Parkinson’s disease can be tailored to individual needs, in terms of lifestyle and the types of symptoms the patient is experiencing. specific cannabis strains contain varying ratios of THC to CBD.

For example, if a patient doesn’t want the intoxication that comes with a high-THC strain, a high-CBD strain may be the answer.  

If an individual prefers pure CBD strains, dried flower and CBD oils can be purchased over the counter online almost anywhere in the U.S.

Another important consideration is the delivery method. Cannabis products come in a wide menu of options including dried flower for smoking or cooking, vape oils, tinctures, capsules, edibles, topicals, patches, and more. 

These medical marijuana strains have been shown to be effective in relieving the symptoms of Parkinson’s disease:

  • GG4

  • Amnesia Haze

  • Blue Cookies

Patients should talk to a knowledgeable budtender about the more effective strains on their menu for their needs. 

In summary, many Parkinson’s disease patients are finding that medical marijuana and CBD products safely provide them with relief from their pain, spasticity, seizures, and other serious side effects. There exists a wide variety of strains, product formulas, and delivery methods. A unique medical marijuana treatment can be formulated for each individual’s needs. 

Treatment options should always be discussed with a qualified healthcare provider. 

Natural Remedy For Parkinsons #4 Chlorella And Borax:

If you have a neurological disease such as Parkinson’s orAlzheimer’s, the importance of removing heavy metals from the body – especiallyfrom the brain and nervous system – cannot be overstated. Heavy metalsaccumulate in the brain and nervous system at a rapid rate and cause damage tothe neurological pathways and “brain inflammation”. Fluoride is one ofthe worst, however, mercury, lead, aluminium and cadmium are also extremely dangerous.Chlorella and borax not only remove these heavy metals completely, theycontinue to prevent further toxic build-ups.

Chlorella is a miracle blue-green algae and one of themost powerful detoxifiers and chelators yet discovered. Whenit’s combined with cilantro, its benefits are enhancedsignificantly. A Russian study found that chlorella, combined with cilantro,was able to remove all heavy metals from the body, including fluoride and mercury,with no adverse or harmful side effects. You can purchase chlorellain powdered form online or from most health food stores. Just make sure you buythe Broken Cell Wall Chlorella as this is the strongest and most bio-available.For dosage recommendations, simply follow the directions on the container.

Naturalremedy For Parkinsons #10 Foods You Must Avoid

There are certain foods that are known to worsen thesymptoms of Parkinson’s and certain foods that are known to help. Healthadvocate, Dr Joseph Mercola, says that Parkinson’s disease is primarily relatedto poor lifestyle choices, particularly poor dietary habits. Increasing yourbody’s natural dopamine levels is also extremely important in your fight againstPD.

The foods and liquids you should be eating and drinkingmore of to help you along include:

·        Clean Filtered Water – Clean filtered water helpsto flush toxins from the body and hydrate the cells .Try and aim to drink at least two liters of water every day, and under nocircumstances drink tap water! Tap water is laced with toxic fluoride and otherchemicals and heavy metals so NEVER drink it. Buy yourself a good quality waterfilter. It’s worth the investment.   

·        Whole Foods and Raw Foods – Eat plenty oforganic mixed berries, green leafy vegetables, liver , fish,eggs, nuts and seeds such as chia and flaxseeds, along with plenty of herbs andspices. When it comes to buying any of these remember fresh is alwaysbest.  

·        Consume Lots of Probiotics – Good gutbacteria are needed for strong immunity and healthy digestive function, whichin turn produces healthy brain and nerve function. You can learn how to makeyour own probiotic rich foods such as kefir, sauerkraut, kombucha and yogurt here…Cultures for Health.  

The foods you should be avoiding or not eating at allinclude:

What Medications Are Used To Treat Parkinsons Disease

Medications are the main treatment method for patients with Parkinson’s disease. Your doctor will work closely with you to develop a treatment plan best suited for you based on the severity of your disease at the time of diagnosis, side effects of the drug class and success or failure of symptom control of the medications you try.

Medications combat Parkinson’s disease by:

  • Helping nerve cells in the brain make dopamine.
  • Mimicking the effects of dopamine in the brain.
  • Blocking an enzyme that breaks down dopamine in the brain.
  • Reducing some specific symptoms of Parkinson’s disease.

Levodopa: Levodopa is a main treatment for the slowness of movement, tremor, and stiffness symptoms of Parkinson’s disease. Nerve cells use levodopa to make dopamine, which replenishes the low amount found in the brain of persons with Parkinson’s disease. Levodopa is usually taken with carbidopa to allow more levodopa to reach the brain and to prevent or reduce the nausea and vomiting, low blood pressure and other side effects of levodopa. Sinemet® is available in an immediate release formula and a long-acting, controlled release formula. Rytary® is a newer version of levodopa/carbidopa that is a longer-acting capsule. The newest addition is Inbrija®, which is inhaled levodopa. It is used by people already taking regular carbidopa/levodopa for when they have off episodes .

Parkinsons Clinical Signs Diagnosis And Rating Scales

Is An Oral L

The three clinical motor cardinal signs of PD, a-/hypo-/bradykinesia, rest tremor, and rigidity, are directly related to the degeneration of dopaminergic neurons. However, other motor symptoms and signs, secondary to degeneration of nondopaminergic pathways, can be described such as loss of postural control, postural stability/balance, and gait disturbance. In addition, the most well-known nonmotor characteristic motor symptoms have also been described. There can be additional psychiatric and autonomic features found, as well as cognitive impairment, sleep disorders, olfactory dysfunction, and pain.

Methodological Limitations Of The Diagnostic Studies

When interpreting the literature about PD diagnosis, the following methodological issues should be considered:

  • lack of long-term prospective clinical and pathological as a reference standard
  • lack of operational definitions such as defining specialists or clinical diagnostic criteria
  • unclear whether investigators were blinded to initial diagnosis
  • sample sizes necessarily limited by the number of cases available with neuropathological outcomes
  • PD trial age groups are often young as studies were performed by neurologists who see a younger population of people with PD
  • most studies included people with established disease lasting some years
  • varying geographical locations
  • some studies are in specialised units and may not reflect the diagnostic accuracy of other units in the UK
  • exclusion of some studies using magnetic resonance volumetry and magnetic resonance spectroscopy as they lacked appropriate population, intervention and outcome criteria
  • lack of statistical details of diagnostic accuracy such as sensitivity, specificity and positive predictive values
  • lack of economic evaluations of SPECT.

Can Medical Marijuana Help Treat Parkinsons Symptoms

Chronic inflammation is a dominant symptom of Parkinson’s disease. Medical marijuana is known to modulate the inflammatory response. This in turn slows the progression and even potentially the onset of neurodegeneration.

Oxidative stress is a culpable factor in the destruction of nerve cells and brain neurons. Cannabis contains strong antioxidant properties and is known to be neural-protective. 

Moreover, Parkinson’s patients who used medical marijuana report a significant decrease in depression and fatigue. 

Home Remedyfor Parkinsons #5 Vitamin D & Vitamin E:

Inflammation and low immunity are two powerful factorsthat contribute to the development and worsening of Parkinson’s disease. Bothvitamin D and vitamin E are strong anti-inflammatories and immune boosters. VitaminD & E also protect our brain cells and can even help damaged neurons regenerate. A deficiency of these key vitamins has also been linked to brain difficultiessuch as poor memory and recall attainability. 

In regards to PD, a study of 157 Parkinson’s patientsfound that the vast majority of them had severe to chronic vitamin Ddeficiencies. The findings, published in the Archives of Neurology in March of 2011, revealed a strong linkbetween inadequate levels of vitamin D and the onset of early Parkinson’sdisease.4

Back in 2002, another study was published in the Archives of Neurology which tracked themental decline of 3,000 men and women diagnosed with Parkinson’s disease over a period of 7 years. The study found the participants whose supplemental vitamin E intakewas higher experienced a 36% reduction in theseverity of their symptoms compared to the rest of the group. Another study, whichappeared in the Lancet Neurology onlinemagazine in 2005, showed that vitamin E may actually prevent Parkinson’sdisease from developing in the first place! 8 

Where to Get Your Vitamin D and Vitamin E From?


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