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Can Wellbutrin Help Parkinson’s

Tremors May Be Nothing To Worry About Or Something More Serious But Don’t Let Them Go Unchecked

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Do you ever notice that you can’t seem to hold a coffee cup still? Or that your hands sometimes tremble so much it interferes with daily chores? Those involuntary hand movements are called tremors. “They’re common in middle and older age,” says Dr. Chizoba Umeh, a neurologist who specializes in movement disorders at Harvard-affiliated Brigham and Women’s hospital. “They’re not life-threatening, but people with severe tremors may have a hard time feeding themselves, dressing, or driving.”

Parkinsons Risk Linked To Cymbalta Celexa Similar Antidepressants: Study

  • July 12, 2018

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New research suggests that the side effects of some antidepressants, such as Zoloft, Celexa and Cymbalta, may increase the risk of Parkinson’s disease. 

In a study published in the August 2018 edition of the Journal of Clinical Psychopharmacology, researchers from the University of British Columbia say there appears to be a link between a number of popular antidepressants, Parkinson’s disease and extrapyramidal symptoms .

According to the findings, the associations were found with the use of Celexa, Cymbalta, Remeron, Lexapro, Paxil, Zoloft, Effexor, Zyban, Wellbutrin, and Prozac.

“Antidepressants are one of the most prescribed classes of medications. A number of case reports have linked these drugs to extrapyramidal symptoms , but no large epidemiologic study to date has examined this association,” the researchers noted. “We sought to quantify the association of EPSs with different antidepressants by undertaking a large pharmacoepidemiologic study.”

Researchers conducted a nested case-control study using data from June 2006 through December 2015, collected by a large claims database in the U.S. They found 3,838 subjects with EPSs and compared them to 38,380 age-matched control subjects.

The effect was not seen throughout all antidepressants, however. Atamet, Requip, Mirapex and a number of others showed no significant association.

Difficulties In Diagnosing Depression In Patients With Parkinson’s

  • Certain symptoms of depression overlap with symptoms of PD ? for example, sleep problems and feeling slowed down occur in both conditions.
  • Some experts think that depression in PD often involves frequent, shorter changes in mood versus a constant state of sadness daily.
  • Many people with PD express less emotion due to the effect the disease has on the muscles of the face. This symptom, called facial masking, makes a person unable to express emotion through facial expressions.
  • Many people with Parkinson’s do not seek treatment because they often do not recognize they have a mood problem or are unable to explain symptoms. For these reasons, it is helpful to ask a caregiver or loved one if he or she has noticed any changes commonly reported in depression.

A Critical Reappraisal Of The Worst Drugs In Parkinsons Disease

What are the worst drugs for Parkinson’s disease patients?  Couldn’t a simple list be assembled and disseminated to the Parkinson community?  Recently Ed Steinmetz, an experienced neurologist in Ft. Meyers, FL pointed out to me, a list approach published in the Public Citizen Newsletter .  The approach was to list every drug associated with a single confirmed or unconfirmed symptom of Parkinson’s disease or parkinsonism.  Parkinson’s disease is defined as a neurodegenerative syndrome , whereas parkinsonism encompasses a wider net of drug induced and other potential causes. In parkinsonism symptoms are similar to Parkinson’s disease, but patients do not have Parkinson’s disease.  Patients and family members confronted with a simple “drug list” approach may falsely conclude that most medicines are bad for Parkinson’s disease, and that any medicine may cause parkinsonism.  This concept is in general, incorrect.  Although the approach is well-meaning, it is in need of a major revision, as Parkinson’s disease and parkinsonism are too complex to summarize by simple lists. In this month’s column I will try to summarize the key information that patients and family members need to know about the “worst pills,” for Parkinson’s disease and parkinsonism.

A Florida Parkinson’s Treatment Blog by Michael S. Okun, M.D.

UF Center for Movement Disorders & Neurorestoration, Gainesville FL


How Is Depression Treated In People With Parkinsons Disease

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Depression must be treated differently in people who have Parkinson’s disease. Many people can be treated with a type of antidepressant called serotonin reuptake inhibitors . However, some other Parkinson’s symptoms may worsen from SSRI use in a very small number of people.

SSRIs shouldn’t be taken if you’re currently taking selegiline . This is a commonly prescribed medication to control other symptoms of Parkinson’s.

If both are taken at once, it could cause serotonin syndrome. Serotonin syndrome occurs when there’s excessive nerve cell activity, and it can be fatal. Symptoms can include:

  • confusion, disorientation, or hallucinations
  • digestive issues like diarrhea or nausea
  • rapid heartbeat, or tachycardia
  • overactive reflexes, or hyperreflexia
  • dilated pupils

Some medications used to treat other symptoms of Parkinson’s, like dopamine agonists, may have an antidepressant effect. These appear to be particularly helpful in those who experience periods when their medication isn’t effective. This is also known as “on-off” motor fluctuation.

Between Prozac Or Wellbutrin Which Is Better For Depression

Both Prozac and Wellbutrin have their advantages and disadvantages. 

Prozac helps with the treatment of depression and anxiety. However, it increases energy levels more than other antidepressants and may not be ideal for people with sleep difficulties. On the other hand, Wellbutrin is useful for treating depression, has few to none sexual side effects, but the patient must be okay with not consuming alcohol. 

Treating Depression In Parkinson’s Disease: Study Results

Patients in all three treatment groups, including the placebo group, showed improvement on a commonly used scale to gauge depression known as the Hamilton Rating Scale.

Those on antidepressants improved more than did those on placebo, Richard says.

On average, those getting Paxil had a 59% improvement. Those taking Effexor had a 52% improvement. Those who got the placebo had a 32% improvement.

Richard evaluated their depression using three other scales and found similar results.

There was no effect on movement ability.

Richard can’t say which antidepressant type is better for treating depression in Parkinson’s disease, she says. The study did not do a head-to-head comparison of the two types.

Each type, SSRI and SNRI, includes many different medicines, so patients have a choice, she says.

Both medicines studied are available as generics, Richard says. At the doses studied, the cost would be about $20 to $30 a month.

Patients reported side effects such as insomnia, constipation, sexual dysfunction, and fatigue. Three patients, including one in the placebo group, had serious side effects. These included chest pressure, bowel obstruction, and heart rhythm problems.

However, only the patient with heart rhythm problems withdrew.

Wyeth Pharmaceuticals provided the venlafaxine XR. Glaxo SmithKline provided the paroxetine.

How To Prevent Parkinsons Disease With Diet And Lifestyle

The number of people diagnosed with Parkinson’s disease and living with this condition is on the rise, with researchers estimating that over 1 million Americans will have this devastating illness by 2020.

Unfortunately, the conventional treatments available for Parkinson’s disease are limited to surgical interventions and medications that come with numerous side effects. But a growing body of research indicates that there are many modifiable risk factors associated with the condition, providing us with clues as to what measures we can take to prevent the onset of the disease. Read on to learn how to prevent Parkinson’s disease by using evidence-based dietary and lifestyle interventions.  

Is It Wrong To Take Prozac And Wellbutrin Simultaneously

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No, it is not wrong but only in consultation with your physician. These two medications together can increase the risk of stroke, which is uncommon in the context of either of the two drugs. Moreover, Wellbutrin may increase the levels of fluoxetine in the blood, which, in turn, increases other side effects.

Treating Depression In Parkinson’s Disease: Perspective

The study has ”critical information” for patients and caregivers, says Michael S. Okun, MD, national medical director of the National Parkinson Foundation. He reviewed the findings.

“The bottom-line message is that treatment for depression in Parkinson’s disease matters,” he says. “An important aspect of this particular study was that it had a placebo group, and that the investigators showed that either antidepressant performed better than placebo for Parkinson patients.”

An editorial that accompanies the study concludes that depression in Parkinson’s patients may be as treatable as it is in the general population.

What Should I Know About Living With Essential Tremor

Essential tremor is not life-threatening, but it can be very distressing for people who have it. The distress is more acute for people with severe symptoms. Simple activities such as eating, writing, or picking up a cup can be challenging and frustrating.As the disease progresses and tremors become more pronounced, many people feel anxious and embarrassed in social situations, making those situations worse. Eating a forkful of food without spilling, drinking a glass of water in a restaurant, speaking in a meeting without a trembling voice, or writing a legible check can become trying tasks.Some people with ET may feel tempted to withdraw from family and friends, but avoiding social situations is not recommended. There are practical tips, in addition to doctor-prescribed treatments, that allow people with ET to maintain active social lives. Staying socially active is an important part of maintaining emotional and physical well-being.

Are There Alternative Therapies For Essential Tremor

Currently, there is no evidence that alternative therapies are beneficial in treating ET. Patients who have tremors that worsen with emotional stress may find relaxation therapies helpful. However, this type of alternative therapy is not a treatment. Some herbal supplements may make tremor worse. Always consult your doctor before trying any alternative therapy.

Tremor As A Side Effect From Taking Antidepressants

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Is it normal to develop a tremor while taking an antidepressant? Which drugs may cause this symptom and how is it treated? Learn more about what a tremor is, the different types of tremors, and what other medications as well as medical conditions which may contribute to a tremor.

When Are Drugs Prescribed To Treat Essential Tremor

When essential tremor often prevents with daily activities, long-term drug treatment is needed. Your healthcare provider will determine which treatment is best based on other medical conditions you may have and based on the safety of the drugs. The goal is to minimize the side effects of drugs while having improvement in function.

With the use of medication, patients may see improvement in the ability to control tremor and improvement in functions like drinking from a cup or using food utensils. More specialized motor functions, such as being able to thread a needle, may not improve.

For patients with mild ET, the effects of the condition can be lessened by the patient’s minimizing exposure to emotional stress and avoiding substances, such as caffeine and nicotine that may increase tremor. In social situations, a person with mild tremor can take a beta blocker drug or drink a small amount of alcohol if such treatments are approved by a doctor.

Drugs most commonly used to treat ET include beta blocking drugs Inderal® , Tenormin® , Betapace® , and Lopressor® .

Antidepressants Aid Depressed Parkinson’s Patients

Two Classes of Medicine Help Depression in People With Parkinson’s Without Worsening Other Symptoms, Experts Say

April 11, 2012 — Certain antidepressantmedications can help treat depression in people with Parkinson’s disease without making the symptoms of the disease worse, according to a new study.

Researchers looked at two common types of antidepressant medicines in the study. They found that both improved depression.

There has been a lingering suspicion that antidepressants may make the symptoms of Parkinson’s worse, but this study may help set aside some of those fears.

“We showed that we have effective and well-tolerated treatments for depression in Parkinson’s,” says researcher Irene Hegeman Richard, MD, associate professor of neurology and psychiatry at the University of Rochester Medical Center.

Depression is the thing that most impacts quality of life,” she says. “It’s present in almost 50% of patients.”

About a million people in the U.S. have the brain disorder, according to the National Parkinson’s Foundation. It leads to shaking or tremors and difficulty with walking, movement, or coordination.

The study is published in the journal Neurology. It was funded by the National Institutes of Health/National Institute of Neurological Disorders and Stroke and Johns Hopkins University School of Medicine.

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Treatment For Tremors Caused By Antidepressants

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Perhaps the best solution for tremors caused by antidepressants is to stop taking the drug causing it and switch to a different medication. Tremor will generally resolve over time after the medication has been ceased, but occasionally a tremor caused by SSRIs may persist.

Sometimes, however, you may be doing so well on your medication that you don’t want to change it for fear of returning depression. If this is the case, your doctor may opt to add an additional medication to control your tremors. Some medications that may be used to manage antidepressant-induced tremors include:

  • Beta-blockers

editorial process

  • Morgan JC, Kurek JA, Davis JL, Sethi KD. Insights into pathophysiology from medication-induced tremor. Tremor Other Hyperkinet Mov . 2017;7:442. Published 2017 Nov 22. doi:10.7916/D8FJ2V9Q

  • Dixit, S., Khan, S., and S. Azad. A Case of SSRI Induced Irreversible Parkinsonism. Journal of Clinical and Diagnostic Research. 2015. 9:VD01-VD02. doi:10.7860/JCDR/2015/11394.5583

  • National Institutes of Neurological Disorders and Stroke. Tremor Fact Sheet. Updated August 13, 2019.

    • Kasper, Dennis L.., Anthony S. Fauci, and Stephen L.. Hauser. Harrison’s Principles of Internal Medicine. New York: Mc Graw Hill education, 2015. Print.

    • U.S. National Library of Medicine. Medline Plus. Drug-Induced Tremor. Updated 09/05/17.

    If It Is Not Essential Tremor What Could It Be

    Tremors can be caused by a variety of other conditions or lifestyle factors. What separates them is the timing of the tremor. It is important to know if the tremors occur at rest, with sustained posture, or with certain movements.

    • Drugs. There are several drugs that can cause tremor:
    • Albuterol .
    • Corticosteroids .
    • Certain antidepressants like Paxil®, Prozac®, Zoloft®, Pamelor®, and others.
  • Other causes:
  • Resting tremors can be caused by certain medications, Parkinson’s disease, or other conditions including multiple sclerosis and stroke.
  • Tremors that change with posture or movement can occur in people with low blood sugar, drug withdrawal, thyroid problems, Parkinson’s disease, multiple sclerosis, or stroke.
  • What Are The Treatment Options For Depression

    Just as the symptoms and causes of depression can differ from person to person, so too can suitable treatment approaches. There are two main types of treatment options for depression: antidepressant medications and psychological counseling . 

    The Parkinson’s Foundation recommends a holistic, comprehensive approach to depression. Although antidepressants are often effective in reducing symptoms, they should seldom be used alone. In most cases, the best approach is a combination of antidepressant medication, counseling, exercise and social support. 

    How can you ease depression in PD? First, share your concerns with your doctor. Many movement disorders specialists now include questions about depression in their exams. If your doctor does not, raise the topic. He or she may recommend medical or nonmedical coping strategies, including the following:

    Make Sure You Get Enough Vitamin D And Omega

    Vitamin D deficiency is associated with an increased risk of Parkinson’s disease, whereas vitamin D supplementation and sunlight exposure are associated with a reduced risk. How does vitamin D combat neurodegeneration in Parkinson’s disease? A high density of vitamin D receptors reside in the part of the brain most affected by Parkinson’s disease; this finding suggests that vitamin D regulates the function of neurons.

    Vitamin D also lessens the severity of autoimmunity and regulates neurotrophins, proteins that induce the survival, development, and function of neurons. Vitamin D is one nutrient you won’t want to skimp on if your goal is to prevent Parkinson’s disease!Safe sun exposure is the best method for boosting vitamin D levels. However, full-body sun exposure is not possible for most people year-round; in this case, I recommend you take cod liver oil and eat fatty cold-water fish, beef liver, and egg yolks to obtain dietary vitamin D.

    Omega-3 fatty acids, like EPA and DHA, are critical for normal brain development and function across the lifespan. Low levels of EPA and DHA increase the risk of neurodegeneration, whereas omega-3 supplementation can help reduce neuron death in the brain, alleviate neuroinflammation, boost antioxidant enzymes, and relieve motor symptoms in PD. EPA and DHA are abundant in seafood, so I recommend consuming two to three servings of seafood per week to achieve a healthy intake of these neuroprotective fatty acids.

    Treating Depression In Parkinson’s Disease

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    Depression in people with Parkinson’s is still under-recognized and under-treated, Richard tells WebMD.

    As doctors have become more aware of how common it is, she says, they have struggled with how best to treat it.

    Older antidepressants known as tricyclic antidepressants are sometimes used, she says. But their use is linked with certain types of heart problems and other side effects.

    Richard’s team studied paroxetine and venlafaxine extended release , comparing it to placebo.

    Paroxetine is an SSRI , which affects levels of the hormone serotonin in the brain, improving mood.

    Venlafaxine extended release is an SNRI . It works by balancing the two hormones to improve mood.

    The 115 patients all had both Parkinson’s and clinical depression. Patients had to be at least 30 years old and free of dementia. They were treated at 20 different centers in the U.S., Canada, and Puerto Rico from June 2005 through March 2009.

    The patients were assigned to one of three groups: paroxetine, venlafaxine, or placebo.

    The patients took a maximum of 40 milligrams of paroxetine or 225 mg of venlafaxine daily.

    The researchers evaluated their depression at the start and throughout the 12-week study. They looked to see if the treatment affected their movement ability.

    Medications For Parkinson’s Disease

    Because the loss of dopamine in the brain is the fundamental problem of Parkinson’s disease, treatment is focused on replacing dopamine to help counter the loss of motor function. Dopamine loss is not the only mechanism involved; finding other, still-unknown factors is a major challenge facing researchers. Until we have the answers, however, drug makers will continue to design medications aimed at helping the brain replace the missing dopamine.

    When symptoms warrant treatment, your neurologist will consider several types of medications to reduce tremor and ease movements.

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    What Are The Symptoms Of Essential Tremor

    The main symptoms associated with essential tremor include:

    • Uncontrollable shaking that occurs for brief periods of time.
    • A shaking voice.
    • Tremors that worsen during periods of emotional stress.
    • Tremors that worsen with purposeful movement.
    • Tremors that lessen with rest.
    • Balance problems, in rare cases.

    Going Off Cymbalta & Starting Wellbutrin adri

    • Please log in to reply
    • 18 posts

    Posted 02 May 2014 – 09:15 AM

    I’m going to post this in both medication’s forums to see what I can find out. 


    I’ve been on cymbalta for less than 6 months and it stopped working and the side effects were too much. On Monday my dr told me to stop taking the cymbalta immediately and started me on wellbutrin. Here’s what my med calendar was supposed to look like…


    Monday – last dose of cymbalta in the morning

    Tuesday – 1 dose of 150mg wellbutrin in the morning

    Wednesday – Morning wellbutrin

    Friday – 1 dose of wellbutrin in the morning and at night


    Starting on Tuesday I was a little bit dizzy and tired but nothing unbearable


    Wednesday the dizziness and tiredness was worse, along with what felt like random earthquakes through my whole body . Felt lethargic all over. I came down with a pretty bad cold on top of all of this.


    Yesterday the dizziness, nausea, and tiredness was almost unbearable. Add on to that my lips feel numb and tingly. Whole body feels flu-like. I am also experiencing a pulsing feeling through my whole body any time I move my eyes or head. I called the doctor and they said to take the wellbutrin at night as well and see how I feel, that it should get better. 



    To me, this sounds like the wellbutrin is the problem, not so much the quitting cymbalta cold turkey. Thoughts?

    Drug Interactions Or Combining The Drugs

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    Consult your physician before combining Wellbutrin with Prozac. Combining these medications may cause complications, such as increasing the risk of seizures. Such difficulties may not occur commonly with either of the two drugs. 

    Moreover, Wellbutrin can augment the levels of Prozac in the bloodstream, which may lead to an increase in other side effects. An individual has a higher likelihood of experiencing strokes with these drugs if they: 

    • Are elderly;  
    • Have a history of seizures;
    • Are experiencing an alcohol or drug withdrawal;
    • Any central nervous system condition, like a brain tumor, or trauma/injury to the head

    In such cases, the physician may prescribe some other medications that do not interact. Otherwise, the individual may be suggested an adjustment in the dosage. Further, the doctor may monitor the patient more regularly to ensure the safe consumption of the medications.

    It is imperative that the patient avoids the consumption of alcohol during the treatment period. Further, the patient must let their physician know of all the drugs they are currently taking, including supplements and herbs. The patient must not stop the medication without discussing it with the doctor first. 

    Herbal Medicine, such as Kratom. Check the Best Kratom for Depression and Anxiety.

    What Other Drugs Will Affect Wellbutrin

    You may have a higher risk of seizures if you use certain other medicines while taking Wellbutrin.

    Many drugs can interact with bupropion. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Wellbutrin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

    Does Anxiety Get Better With Wellbutrin

    Yes, Wellbutrin does help with anxiety. One case study reported that 150 milligrams of a daily dose of Wellbutrin helped with anxiety and panic symptoms in an individual with panic disorder. Anecdotal evidence exists to show the effective treatment of anxiety using Wellbutrin along with other medications.

    Warning Disclaimer Use For Publication

    WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

    DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

    If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

    Can I Take Bupropion With Hydroxyzine

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    Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.

    In respect to this, can you take Wellbutrin and hydroxyzine together?

    This report displays the potential drug interactions for the following 2 drugs: Vistaril Wellbutrin Drug Interaction Classification.

    Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.

    Additionally, what anxiety medication can you take with Wellbutrin? Wellbutrin and Drug Interactions

    • Paroxetine
    • Carbamazepine

    Also, what can you not take with hydroxyzine?

    Do not use with any other antihistamines applied to the skin because increased side effects may occur. Hydroxyzine is very similar to cetirizine and levocetirizine. Do not use these medications while using hydroxyzine.

    Is hydroxyzine the same as buspirone?

    Hydroxyzine and buspirone belong to different drug classes. Hydroxyzine is an antihistamine with anticholinergic and sedative properties; buspirone is an azapirone anti-anxiety medication. Side effects of hydroxyzine and buspirone that are similar include dizziness, nervousness, and nausea.

    Parkinsonism Falls And Fracture Risk

    All forms of parkinsonism, both PD and DIP, have implications for bone health. A 2014 meta-analysis on PD and fracture risk concludes that PD increases the risk of fracture.4

    Given that the symptoms of parkinsonism affect balance, motor skills, gait, and the body’s ability to control movement, it is no surprise that people with PD are more likely to experience a fall than people without PD. Here is an excerpt from a 2016 study comparing the incidence of falls and fracture in PD patients:

    It is estimated that 60.5% of patients with PD experience at least one fall and 39% have recurrent falls. The high frequency of falls consequently contributes to the increased risk for fractures in PD patients, which has been estimated to be approximately two times the risk in healthy controls. It has been estimated that 76% of falls in PD patients require health care services and 33% result in fractures. Falls and fractures may result in a series of unfavorable outcomes, such as disabilities and death. Furthermore, among PD patients with fractures, the mortality rate is approximately 10.6%.5

    All too often, doctors prescribe these drugs without appropriate consideration of this risk. This excerpt from a study on DIP clarifies the danger of accepting a prescription of an unnecessary or inappropriate prescription drug:

    Shockingly, the drugs that cause DIP are still being prescribed. This yet one more example further proving that the FDA’s drug approval process is useless.


    Other Medications That Cause Tremors

    Other psychiatric medications—such as lithium and Depakote —may also commonly cause tremor.?? Antipsychotic medications, particularly the older agents , may cause a tremor similar to Parkinson’s disease.

    Extrapyramidal side effects of these drugs may also include dystonia , tardive dyskinesia , and akathisia, a feeling of restlessness which may sometimes mimic a tremor.??

    In addition, there are a wide variety of other prescription drugs which may cause tremor. These include:

    • Anticonvulsants
    • Some heart and blood pressure medications
    • Stimulants such as caffeine and amphetamines

    Common Symptoms For These People *:

  • Nausea : 11 people, 34.38%
  • Freezing Phenomenon: 8 people, 25.00%
  • Weight Decreased: 8 people, 25.00%
  • Hallucinations : 8 people, 25.00%
  • Malaise : 8 people, 25.00%
  • Abnormal Dreams: 8 people, 25.00%
  • On And Off Phenomenon: 8 people, 25.00%
  • Dyskinesia : 7 people, 21.88%
  • Constipation: 7 people, 21.88%
  • * Approximation only. Some reports may have incomplete information.

    Is Prozac Different From Wellbutrin

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    No, Prozac and Wellbutrin are different from each other, although both are prescribed for depression. Prozac is a Selective Serotonin Reuptake Inhibitor , which restricts the reabsorption of serotonin. On the other hand, Wellbutrin is an aminoketone, which restricts the reuptake of the neurotransmitters noradrenaline and dopamine. 

    Depression And Parkinson’s Disease

    Depression is a mood disorder that affects more than half of those with Parkinson’s.1,2 Its symptoms can affect the way you feel and think, and cause changes to your regular patterns of sleeping and eating, as well as your ability to go to work and interact with friends and family. There are different types of depressive disorders and the symptoms can vary.2

    Depression can be diagnosed by a physician and can generally be effectively treated with talk therapy and medications. The treatment approach is very individual based on the symptoms you are experiencing, other medications you take, and your personal medical history along with Parkinson’s stage. No one drug is effective for everyone, and it may take trying several before finding the one or combination that works best for you. It is important to carefully follow the prescribed instructions when taking antidepressants and report any side effects to your physician.

    The Connection Between Pd And Drug

    In addition to potentially causing parkinsonism in the general population, these medications should definitely be avoided in people who have parkinsonism from other causes, such as PD. APDA has created a list of Medications to be Avoided or Used With Caution in Parkinson’s Disease. It is important to note that there are anti-psychotics and anti-nausea medications which do not cause parkinsonism and can be used safely by people with PD.

    Sometimes, a person without a diagnosis of PD is prescribed a medication which leads to a side effect of drug-induced parkinsonism. The prescribing physician may stop the new medication, but the parkinsonism does not resolve. The patient remains off the medication with continuing symptoms, and eventually is given a diagnosis of PD. In this scenario, that person most likely had dopamine depletion in the brain which had not yet manifested as a clinical symptom. The prescription medication that blocked the dopamine receptor, was the proverbial “straw that broke the camel’s back”, inducing the full-fledged symptoms of dopamine depletion and revealing that the person did in fact have PD.

    The differences of PD vs drug-induced parkinsonism

    There are key differences to note between parkinsonism from PD and parkinsonism as a side effect of medication.


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