Friday, January 28, 2022
Friday, January 28, 2022
HomeTreatmentsCan Parkinson's Cause Seizures

Can Parkinson’s Cause Seizures



Have You Come Across Advice That Those With Parkinsons Should Avoid Too Much Refined Sugar Or Perhaps Youre Aware Of New Research Linking Diabetes And The Condition We Go Behind The Headlines To Find Out What Is Actually Going On

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Over the last decade, a war on sugar has started. In March 2016 the government announced that a tax on sugary soft drinks would be introduced in the UK from 2018. At the same time, we’ve seen a gradual increase in messaging that healthy eating, particularly limiting your intake of sugar, is essential for a healthy body.

The main aim of this war is to curb a growing obesity pandemic. And while it’s too early to draw any conclusions about these initiatives on the patterns of obesity in the UK, studies have suggested that simply reducing the sugar content of sweetened beverages by 40% over five years could result in roughly half a million fewer obese adults. As our collective national waistline shrinks, the hope is we will also see a reduction in a range of health conditions from heart problems to cancer, diabetes to osteoarthritis.

It Quickly Became Clear That Most People Dont Know That Having Dementia Particularly Alzheimers Disease Can Increase Your Risk Of Seizures

In our group, around 1 in 8 patients with dementia described episodes which we believe could have been epileptic seizures.

We interviewed our participants one year later and found that those who had described having had epileptic seizures previously performed less well on memory tests than those who showed no evidence of epilepsy. 

Can A Patients Ability To Make Decisions In The Last Days Of Life Be Impaired And How Is This Managed

In a North American study of 47 carers of idiopathic PD patients in the last months of life most described the goal of care as comfort, and almost half “of the patients were described as unable to make any decisions in the last month of life.” 10

When presenting, the patient may already be unable to communicate their symptoms and care preferences due to cognitive impairment and confusion. Also, there might be a physical difficulty in communication from severe rigidity. Care should be taken in considering the presence and consequent treatment of an intercurrent illness, and whether dopaminergic medication is exacerbating confusion due to hallucinations and/or psychosis.27 

Continued attempts at verbal and non-verbal communication should be made throughout given the often fluctuating symptoms associated with PD and possible improvement in the intercurrent illness. In the absence of a next of kin or other person who is able to inform the clinical team, decisions should be made on a best interest basis as recommended in end of life care guidance.30

Stage Four: Symptoms Are Severe And Disabling And You Often Need Assistance To Walk Stand And Move

Stage Four Parkinson’s disease is often called advanced Parkinson’s disease. People in this stage experience severe and debilitating symptoms. Motor symptoms, such as rigidity and bradykinesia, are visible and difficult to overcome. Most people in Stage Four aren’t able to live alone. They need the assistance of a caregiver or home health aide to perform normal tasks.

Stage Three: Symptoms Are More Pronounced But You Can Still Function Without Assistance

PPT

The third stage is considered moderate Parkinson’s disease. In this stage, you’ll experience obvious difficulty with walking, standing, and other physical movements. The symptoms can interfere with daily life. You’re more likely to fall, and your physical movements become much more difficult. However, most patients at this stage are still able to maintain independence and need little outside assistance.

What Are The Considerations For Pain Management In The Last Days Of Life In Pd

It is important to consider that pain can be a risk factor for, and associated with, many other symptoms which might be the presenting features in a patient with complex or advanced PD. These include a new or worsened confusion, hallucinations, agitation and symptoms of depression or apathy.

As well as being an underlying cause of another symptom, pain can also be the symptom of other features of PD, such as rigidity, dyskinesia, but also non-motor features, for example, depression and fatigue.

Identifying whether pain is at the root of the presenting complaint and what might be causing the pain is therefore the most important part of the initial history from the patient and the carer. Then using the clinical examination to confirm findings from the history and identify any features not already elicited such as abnormal posturing, or dystonia.

A recent review into the pathophysiology and treatment of pain in PD suggests simple analgesia with paracetamol and non-steroidal anti-inflammatory drugs but advises caution with opiate analgesia as constipation is a recognised problem in PD patients.25 The review mentions, however, the lack of evidence for many widely used analgesics specifically in PD.26

Relationship Between Disrupted Neuronal Connectivity And Epileptic Seizures

Epilepsy is considered a disease of network dysfunction.47,48 At a microscopic level, both simple and complex partial seizures involve disruptions in the excitatory interactions between cerebral cortex pyramidal cells.49 From a neurophysiology view, the EEG-graphic representation of an epileptic event is characterized by the paroxysmal onset of hyper-synchronized sharp waves disrupting the neuronal background activity. This activity is often multifocal, reflecting a broader network dysfunction.50,51 Moreover, TMS studies demonstrate similar neurophysiologic features between epilepsy and PD characterized by a state of increased cortical excitability as indicated by reduced intra-cortical inhibition and increased intra-cortical facilitation observed in both patient populations.25,52–55 As mentioned before, in PD, cortical neurons innervating the basal ganglia become hyperexcitable, possibly as a compensatory mechanism following the incremental rise in the output threshold of striatal dopaminergic neurons. As such, it would not be surprising if this putatively maladaptive phenomenon may eventually lead to the generation of epileptiform activity. While epidemiologically, epilepsy-increased comorbidity in patients with PD remains questioned,13,56 our group published the largest case series of patients with PD with concomitant epilepsy57 raising the possibility that epileptic activity in these patients may indeed be under-diagnosed and under-recognized.

What Are The Important Points Regarding Apomorphine At The End Of Life

Apomorphine is a dopamine agonist, which is given as a subcutaneous infusion either continuously or intermittently and also as single subcutaneous injections. An overview of studies into apomorphine use shows improvement in motor off periods and in dyskinesias.39

Apomorphine has side-effects similar to other dopaminergic medication but also notably nausea and vomiting. Ondansetron is not recommended for nausea in patients using apomorphine due to adverse effects.21

Subcutaneous apomorphine has been used at the end of life in a patient with advanced PD although with the recommendation that this is by a healthcare professional experienced in its use.40

Subclinical Or Atypical Epileptic Seizures Could Masquerade As Non

Animal Models Of Chronic Epilepsy

While the non-motor questionnaire and non-motor symptoms scale 73,74 allow improved detection and tracking of NMD-PD, the symptoms often remain under-recognized and under-appreciated by clinicians and caretakers. Recently, six different clinical phenotypes of PD were recognized on the basis of prevalent NMS-PD.75 These non-motor signatures included cognitive impairment, apathy, depression/anxiety, REM behavioral disorder , lower limb pain, and weight loss/olfactory dysfunction. This distinction may help in promoting the incorporation of NMS-PD into routine assessments, emphasizing the importance of these features for an adequate appreciation of the patient’s clinical picture. On the other hand, a rigid categorization may challenge the flexible and consistent monitoring of these dynamic and overall nonspecific symptoms along the disease course.

In the following section, we will focus on clinical features frequently displayed by patients with PD that may signal an ongoing subclinical or non-motor epileptic event masquerading as NMS-PD.

What Are The Important Points Regarding Duodopa At The End Of Life

Duodopa is a continuous infusion of dopaminergic medication administered as a gel into the gut, pumped via a percutaneously inserted gastrostomy tube . There is a requirement for care of the stoma and PEG tube together with functioning of the pump by the patient or carer.41 It reduces the time in motor off periods in advanced PD and quality of life.42 There is evidence of effective treatment up until death from within a case series.43

Cat Head Shaking Like Parkinson’s: Potential Causes And Treatments

 

When it comes to cats in general, most pet owners universally agree that their fluffy friend tends to act rather oddly from time to time. Nonetheless, in a couple of cases, strange behaviors in cats are early symptoms of serious diseases which require urgent attention. That means you should not underestimate the issue of “cat head shaking like Parkinson’s”, especially if your pet seems fine up until very recently. As with humans, the earlier you detect health problems in your cat and get it diagnosed, the easier the treatment. But what is the cause of the head shaking anyway? Is it possible for the vet to prevent future resurgent?

If you are searching for answers to questions above and information regarding the “cat head shaking like Parkinson’s” issue, this article is for you. Down below, you would be introduced to everything you must know about the head shaking including potential causes and solution. Generally speaking, you could take care of any health problem in cats as long as you act promptly and decidedly. It’s not difficult to keep your cat in good condition, you only have to pay attention. So just put what you learn here into practice and your pet would get back in shape in no time.

What Are The Risks Of Not Receiving Any Dopaminergic Medication

There is the possibility of neuroleptic malignant-like syndrome , a life-threatening and distressing condition resulting in rigidity and fever, from withdrawal of therapy.31 This can also occur with sudden cessation of Deep Brain Stimulation .32,33,34 To reduce the risk of this, dopaminergic therapy at the end of life should be continued.27 It should also be noted that in a patient dying of another condition, whose PD is still responsive to dopaminergic medication, the cessation of this also risks aspiration pneumonia.35 Transdermal rotigotine can be used in patients in whom a NG tube may cause excessive distress or is not possible. The dose should be calculated with an accepted converter.36

Which Medications Can Make Confusion And Hallucinations Worse

Epilepsy: Facts, Disease Prevention and Treatment Strategies

As PD progresses, non-motor symptoms including psychosis and hallucinations become more prominent both for the patient and caregivers.9 Dopaminergic medication can exacerbate these symptoms and this can be reduced through a “last in, first out approach.” 27,28 Medications that have an anticholinergic effect also may cause or worsen acute confusion and the anticholinergic burden in the patient’s medication history should be considered.29

Does Epilepsy Or Epilepsy Medications Affect Fertility In Men

As explained below, epilepsy medications can decrease sperm count.

But because men produce so much sperm, usually epilepsy medications donotaffectfertilityinmales.

There are very few described cases of epilespy medications causing infertility in males. These cases are temporary. After changing medications, sexual function, sperm count and sperm function all improve.

Parkinson’s Disease Caused By Stroke: Vascular Parkinsonism

A stroke involving the substantia nigra or basal ganglia is called vascular Parkinsonism. Similar to other strokes, damage is caused primarily by a lack of blood supply to these regions of the brain. Generally, the strokes associated with Parkinsonism are termed small vessel strokes as they aren’t normally catastrophic. Diagnosis of small vessel strokes can be confirmed with diagnostic tests such as CT or MRI of the brain.

It typically takes several small strokes to produce the symptoms of vascular Parkinsonism. In some cases, small vessel strokes can also produce a type of dementia called vascular dementia. As such, it is not unusual for people who have vascular Parkinsonism to also have vascular dementia.

What To Do With Deep Brain Stimulation At The End Of Life

Deep brain stimulation uses an Implantable Pulse Generator, usually placed in the infraclavicular area, connected to leads within the brain. There is a remote programmer, and also a charging unit in the case of a rechargeable device, which are given to the patient and their carer. It improves dyskinesias and also has a levodopa sparing effect.37

Deactivation of DBS may lead to increased symptom burden as mentioned in the section above and so awareness of features of PHS should be considered if there is failure at the end of life. Supportive treatment should be given if possible,38 and anticipation of symptoms of distress from rigidity and fever.

After death, deactivation of the device with the patient’s handheld programmer is required before removing the pulse generator and battery in the case of a cremation.

How To Talk To Someone With Hallucinations Or Delusions

Valley Neurology

  • It is usually not helpful to argue with someone who is experiencing a hallucination or delusion. Avoid trying to reason. Keep calm and be reassuring.
  • You can say you do not see what your loved one is seeing, but some people find it more calming to acknowledge what the person is seeing to reduce stress. For example, if the person sees a cat in the room, it may be best to say, “I will take the cat out” rather than argue that there is no cat.

Page reviewed by Dr. Chauncey Spears, Movement Disorders Fellow at the University of Florida, a Parkinson’s Foundation Center of Excellence.

Fertility: Can A Man Or Woman With Epilepsy Have A Baby

This is an article from the Safe Pregnancy in Epilepsy patient guide.

Epilepsy does not decrease fertility. But Epilepsy medications can affect fertility.

Epilepsy medications can affect the reproductive system in women. Some medications like valproate can cause PCOD.  Epilepsy medications can cause temporary problems in getting pregnant.

Some epilepsy medications can decrease sperm counts. However, epilepsy medications usually do not decrease fertility of males.

Stage One: Symptoms Affect Only One Side Of Your Body

The initial phase of Parkinson’s disease typically presents with mild symptoms. Some patients will not even detect their symptoms in the earliest phases of this stage. Typical motor symptoms experienced in Stage One include tremors and shaking limbs. Family members and friends may begin to notice other symptoms including tremor, poor posture, and mask face or loss of facial expression.

The Relationship Between Parkinsons Disease And Sleep

It’s unclear whether poor sleep causes parkinsonian symptoms to worsen or whether worsening parkinsonian symptoms cause poor sleep. In many cases it’s likely a case of bidirectionality, with each one exacerbating the other.

Fragmented sleep and sleep deprivation appear to leave the brain more vulnerable to oxidative stress, which has been tied to the development of Parkinson’s disease. Parkinson’s disease is not usually diagnosed until individuals have developed sufficient motor symptoms, by which time a significant portion of brain cells have already been damaged. If poor sleep quality or having sleep disorders foreshadows the development of parkinsonian symptoms, these could be useful in early diagnosis of the disease.

More research is needed to clarify the multifaceted relationship between Parkinson’s disease and sleep. A better understanding of this connection may offer medical experts the unique opportunity to screen at-risk individuals and perhaps delay the onset of the disease.

Parkinsons Sleep Problems: Diagnosis And Treatment

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Parkinson’s disease is chronic and progressive, meaning it tends to get worse over time. However, there are treatment options that can help manage symptoms and allow patients to get more restful sleep.

The simplest way to start sleeping better with Parkinson’s disease is by adopting healthy sleep habits. Sleep hygiene tips for Parkinson’s disease sufferers include:

  • Sticking to regular bedtimes
  • Following a consistent bedtime routine with soothing activities such as listening to music or reading a calming book
  • Getting regular exercise, preferably early in the day
  • Getting adequate exposure to light, whether outdoors or through light therapy
  • Avoiding long naps and naps late in the day
  • Creating a cool, dark, and comfortable sleeping environment
  • Restricting bedtime activities to sex and sleep only
  • Turning off screens an hour before bedtime
  • Reducing liquid intake before bedtime
  • Avoiding caffeine, alcohol, and tobacco
  • Eating a healthy diet and avoiding large meals at night

Light therapy, exercise, and deep brain stimulation have been successfully used to improve overall sleep quality and to treat specific conditions, such as REM sleep behavior disorder, in patients with Parkinson’s disease. Cognitive behavioral therapy for insomnia has proven effective at reducing insomnia in healthy adults, although further research is needed on the effects of CBT in patients with Parkinson’s disease.

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What Is The Link Between Seizures And Dementiablog

There are some symptoms of dementia that are more commonly known, such as memory loss. Seizures are a less common symptom of dementia that are not as understood. Hear from one of our dementia researchers who has been studying seizures in people with the condition.

How common are epileptic seizures in dementia? Who is most at risk of having them? What do these seizures look like? What effect do they have on how someone’s memory changes over time?

These are the questions that I have been researching since starting my PhD in 2016. I’m a student funded by Alzheimer’s Society as part of the University of Exeter doctoral training centre.

Do Epilepsy Medications Affect Fertility In Women

Yes. Some medications can.

Please note that these epilepsy medications decrease fertility. They do not abolish it. Many women get pregnant while taking these medications.

Epilepsy medications decrease fertility in women in 2 different ways:

Valproate:

Valproate is one of the older seizure medications. It can disrupt a female’s reproductive cycle. Valproate may cause a condition called Polycystic Ovarian Disease .

PCOD causes irregular cycles. PCOD can prevent the female’s eggs from developing normally. As a result, patients with PCOD find it more difficult to become pregnant.

“Enzyme Inducing seizure medications”:

The liver gradually inactivates hormones floating in the blood. This gives the hormones some time to act on various body parts.

Some seizure medications are called “Enzyme Inducers“. They can cause your liver to go into overdrive. It starts inactivating hormones rapidly! The hormones include estrogen & progesterone. These sexual hormones are important for becoming pregnant.

These “Enzyme Inducing” medications include:– Phenobarbital– Carbamazepine– Oxcarbazepine

Phenobarbital really pushes the liver into overdrive! This decimates hormones. Thus, phenobarbital may produce temporary infertility.

The other medications push the liver less hard. But according to some studies, in some cases these epilepsy medications decrease fertility. In my own practice, I find this to be uncommon.

There Are Two Common Types Of Epileptic Seizures:

Generalised tonic-clonic seizures

Most of us are familiar with the kind of epileptic seizures we see on TV or in films. People become unresponsive, they fall to the ground, become stiff and their whole-body shakes in a convulsion.

Generalised tonic-clonic seizures are hard to miss. But this is not what most epileptic seizures look like. 

Focal onset seizures

Most epileptic seizures in people with dementia are known as focal onset seizures. These can involve brief periods of increased amnesia or unresponsiveness. We see involuntary repeating movements, often of the hands and arms, or of the face .

Understandably, the latter are more easily missed, especially as the person affected will often quickly be back to normal afterwards..

Parkinsons As A Disease Of Neuronal Connectivity

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The clinical manifestations of neurodegenerative disorders have been traditionally described from an impaired neuronal circuitry perspective.14 Technological advancements have led to a surge of studies investigating the impact PD has on neural excitability and connectivity utilizing electroencephalogram , neuromodulation techniques, imaging modalities, and graph-analytical methods. Although the field of PD has been somewhat slower to incorporate these concepts compared to other disease models, clinicians now generally acknowledge the complex, multifaceted nature of the disease and the need to pursue multidimensional approaches to study it.

To further establish the clinical applicability of connectome network dysfunction, studies have demonstrated that circuit-specific modulatory therapies, such as repetitive TMS, can alleviate various symptoms of PD, from memory and motor symptoms to depression in PD.31–34 Although from a therapeutic standpoint, there is much to streamline and corroborate with respect to repetitive TMS paradigms and methodologies, there is no denying the potential to providing individualized circuit-specific modulatory therapies.35

Why Do Parkinsons Patients Have Trouble Sleeping

Despite having daytime tremors, Parkinson’s patients do not shake in their sleep. However, both Parkinson’s disease itself and the medications used to treat it can give rise to a number of sleep problems that lead to insomnia and excessive daytime sleepiness.

Patients with motor symptoms may have trouble adjusting sleeping positions to get comfortable.  Others may experience distressing nocturnal hallucinations when trying to fall asleep. These may be a result of medications or cognitive impairment.

In turn, excessive daytime sleepiness may occur as a consequence of sleeping poorly at night. It may also be triggered by medications. Parkinson’s patients who suffer from EDS may be at a higher risk of accidents and unable to safely carry out activities such as operating a motor vehicle.

Since insomnia frequently goes hand-in-hand with anxiety and depression, it may be a contributing factor to sleep problems in people with Parkinson’s disease. For that reason, doctors often look for mental health disorders in people with Parkinson’s disease who have sleep problems.

Why Choose Ohio State For Treatment Of Myoclonus

Physician Expertise: All of our movement disorders specialists are board certified neurologists who have received additional fellowship training in movement disorders.

Multidisciplinary Team: Because movement disorders overlap with a number of other nervous system disorders, we have an integrated network of neurology subspecialists who work together, including epilepsy specialists and sleep medicine specialists. In addition, we have physical therapists who specialize in movement disorders and a neurology social worker who connects you to medical and community resources.

Can Seizures Be Managed In People With Dementia

There is good news. There are medications that are effective at reducing, and hopefully stopping, epileptic seizures.

If you think that you, or someone you know with dementia may be having epileptic seizures you should tell a doctor. They might want to perform some extra tests, and may want to start some extra medications to treat this problem.

What we don’t know yet is whether starting treatment for epilepsy might help to slow down dementia and whether it might help keep people’s memory function better for longer.

We have learned so much about the brain – but there is still so much to discover.

Support dementia research

Alzheimer’s Society is working tirelessly to challenge perceptions, fund research and improve care and support. We rely on your donations. Let’s take on dementia together.

The Use Of Levodopa And Peripheral Neuropathy

Parkinsons

There are reports in the literature that levodopa use may increase the risk of peripheral neuropathy, although other studies suggest that this is not the case. There are studies that demonstrate for example, that cumulative Levodopa exposure correlates to prevalence of PN in people with PD. Other studies however, demonstrate no difference in the prevalence of PN whether the person was treated with Levodopa or not, suggesting that Levodopa treatment does not play a role in development of PN.

Another area of research that emerges from the literature is the potential role of Vitamin B12 deficiency in the development of PN in those with PD. Some studies suggest that Vitamin B12 deficiency is a more common cause of PN among those with PD than those with PN who do not have PD.

There is also research that suggests that levodopa treatment may contribute to PN through impairment of Vitamin B12 metabolism, leading to Vitamin B12 deficiency. Taking COMT inhibitors such as Entacapone may protect against this complication.

Regardless, if PN is diagnosed in anyone, whether they have PD or not, and whether they take Levodopa or not, Vitamin B12 and various other markers of Vitamin B12 metabolism should be tested. If Vitamin B12 levels are low or even low-normal, a person should take Vitamin B12 supplementation, which may help with the symptoms of PN. Other causes of PN, many of which can be checked with various blood tests, should be investigated as well.

Peripheral Neuropathy And Parkinsons Disease

A number of studies have tried to determine if PN is more common among people with PD as opposed to people without PD. PN is a relatively common condition in the general population, which makes it difficult to ascertain whether or not it is even more common among people with PD.

The available studies have varying results and are difficult to compare with each other as they:

  • Include different types of populations of people with PD
  • Assess peripheral neuropathy differently
  • Assess for causes of peripheral neuropathy differently

A recent review looked at all the available data and determined that large fiber neuropathy was present in 16% of patients with PD, about double the prevalence of this condition in the general population. Skin biopsy-proven small fiber neuropathy was present in over 50% of people with PD, although this result was based on a small sample of patients.

What Symptoms Can Be Expected In Advanced Pd

  • Pain – 86%
  • Shortness of breath – 54%
  • Problems in swallowing – 40%14

In an analysis of 339 death certificates and medical notes in the UK, pneumonia was found to be a “terminal event in 45%”.13

Caregiver distress with choking and the risk of “choking to death” is also mentioned in a separate study in to experiences regarding all stages of PD.4

In a survey of symptoms and their association with quality of life, in those patients with advanced disease, uncontrolled pain, anxiety and hallucinations were significantly associated with poor quality of life.9

Seizures are also noted in a description of the last phase of Parkinsonian syndromes,15 and in retrospective studies of PD patients’ overall.16,17

These above symptoms often occur on the background of weight loss, pain, and cognitive impairment. It is important therefore to note which medications given at the end of life may exacerbate these symptoms, and which should be considered in anticipation of them.

Does Epilepsy Affect The Reproductive System

No.

There is some controversy about this topic. But, recent research shows that Epilepsy does not affect fertility.

For example:A recent US study looked at women who were trying to get pregnant. They studied both women with epilepsy, and women without epilepsy.

Most women became pregnant in less than 1 year. Women with epilepsy were equally likely to become pregnant.

So, what is the controversy?

Older research shows that Epilepsy patients may have trouble getting pregnant. There is a simple reason for the difference between newer and older studies.

Patients in earlier studies were on older medications like Phenobarbital. Older epilepsy medications can decrease fertility .

In summary, Epilepsy itself does not affect fertility. But in some cases, older epilepsy medications decrease fertility. Read more below.

Can Medical Marijuana Treat Seizure Disorder

Epilepsy: Causes, Symptoms, Seziure Types, Diagnosis ...

Cannabis and its components may offer some relief for people with seizures. Even in ancient times, marijuana was used to manage seizure disorders. Modern medicine also recognizes weed’s potential in treating seizures. But what is the best weed for epilepsy?

The FDA has approved Epidiolex, a brand name product that contains CBD, as a treatment for epilepsy subtypes Dravet syndrome and Lennox-Gastaut syndrome. Recent studies have also shown the benefits of CBD in treating seizures. 

However, most studies concluded that CBD may be safer and more effective in treating seizures than the psychoactive THC constituent of marijuana. In many studies, CBD was prescribed alongside traditional anti-seizure medications, and the combination resulted in an improvement of seizures.

Doctors, however, warn that you should not try to self-medicate with weed if you have a history of epilepsy or seizures. Since it can be hard to control seizures through self-medication, you should first consult with your neurologist about medical cannabis for seizure treatment.

Get seizure treatment via marijuana strains. Click the button below to get your medical marijuana card.

 

 

Get Your Medical Marijuana Card From Mdberry

At MDBerry, we will be glad to evaluate your health situation and determine whether you can benefit from medical marijuana for seizure treatment. If that is the case, we will help you obtain your medical cannabis certification quickly and affordably. When you choose MDBerry, you can rest assured you are getting the best treatment possible. Our certified MMJ physicians are skilled and trained on how medical cannabis can benefit a wide array of health conditions.

Contact Us at MDBerry for seizure treatment or click the banner below to book your appointment.

 

Why Do People With Dementia Develop Seizures

Ultimately, anything that changes the structure of the brain can cause seizures. 

This happens for some people after a stroke, a head injury, or with a brain infection like meningitis. A similar problem is happening in the brain in dementia. As cells in the brain die and the brain shrinks this can lead to epilepsy. 

In addition, we know that two proteins that build up in the brain of people with Alzheimer’s disease – amyloid and tau – affect how the brain’s nerve cells communicate with each other.

Sometimes these nerve cells can become ‘hyper-excitable’, meaning they can behave uncontrollably, causing epileptic seizures.

How Common Is Parkinson’s Disease Psychosis

Between 20-40% of people with Parkinson’s report the experience of hallucinations or delusions. When followed as the disease progresses over the years, this number increases. The increase does not mean that the hallucinations are persistent across the majority of patients. However, it is important to note that these statistics sometimes include “delirium,” in which the symptoms are temporary due to medication that needs to be adjusted or infection that needs to be treated, and “isolated minor symptoms” or “minor hallucinations,” including illusions, where instead of seeing things that are not there , people misinterpret things that are really there. These are the most common types of psychosis in people with PD, with different studies placing the occurrence between 25-70% of people with Parkinson’s. Typically, if the person with PD only has these minor hallucinations, their doctor will not prescribe an antipsychotic medication, though more significant psychosis that requires medication may develop over time. In one study, 10% of those with minor hallucinations had their symptoms resolved within a few years, while 52% saw their symptoms remain the same and 38% saw their psychosis symptoms get worse.

We recommend that people with Parkinson’s not use a single percentage to represent the prevalence of hallucinations and PDP. Parkinson’s is a complex disease and as it progresses the percentages and risk of symptoms will change.


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