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Thursday, June 16, 2022
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Can Parkinsons Be Cured If Caught Early

Parkinson’s Disease Symptoms: Life Expectancy

How early can Parkinson’s be diagnosed?

Even though Parkinson’s disease is a serious, progressive condition, it is not considered a fatal illness. People who have Parkinson’s disease usually have the same average life expectancy as people without the disease.

But when the disease is in its advanced stages, Parkinson’s symptoms can lead to life-threatening complications, including:

  • Falls that lead to fractured bones
  • Pneumonia
  • Choking

Thinking about the progression of Parkinson’s disease can be frightening. But proper treatments can help you live a full, productive life for years to come. And researchers hope to one day find ways to halt the progression of Parkinson’s and restore lost functioning.

How We’re Speeding Up The Search For A Cure

We believe that new and better treatments are possible in years, not decades, and we have a clear strategy for making this happen. This includes:

Medications For People With Parkinsons Disease

Symptoms of Parkinsons disease result from the progressive degeneration of nerve cells in the brain and other organs such as the gut, which produce a neurotransmitter called dopamine. This causes a deficiency in the availability of dopamine, which is necessary for smooth and controlled movements.;Medication therapy focuses on maximising the availability of dopamine in the brain. Medication regimes are individually tailored to your specific need. Parkinsons medications fit into one of the following broad categories:;

  • levodopa dopamine replacement therapy
  • dopamine agonists mimic the action of dopamine
  • COMT inhibitors used along with levodopa. This medication blocks an enzyme known as COMT to prevent levodopa breaking down in the intestine, allowing more of it to reach the brain
  • anticholinergics block the effect of another brain chemical to rebalance its levels with dopamine
  • amantadine has anticholinergic properties and improves dopamine transmission
  • MAO type B inhibitors prevent the metabolism of dopamine within the brain.

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Important Supplements That May Help

Once you;stop putting toxins;into your body and eat clean, the trillions of cells in your body will be;able to start living normally again. Eating the right foods and taking the necessary supplements will now begin to boost your brain health and healing.

Here are some supplements;that will speed up the reversal of PD symptoms:

  • Magnesium:; First and foremost on the list is magnesium. Low intake of this mineral magnesium, enables;the deposition of excess calcium, heavy metals and toxins in the brain that leads to Parkinsons and Alzheimers diseases. When there is adequate presence;of magnesium, heavy metals cannot be absorbed in the small intestines. Magnesium plays a vital role in protecting neurons from the lethal effects of aluminium and mercury poisoning.
  • B vitamins:; A deficiency in;vitamins B9 and B12 can cause brain problems that will initially manifest as depression, anxiety or even psychosis. The other B vitamins are useful for protecting against age-related brain wasting, and possibly prevent memory loss.
  • Glutathione: ;Glutathione is the mother of all antioxidants;and is powerful in neutralizing free radicals damage and greatly reduce oxidative stress that destroy neurons.
  • Grape seed extract: ;Has;super antioxidant effect that reduces DNA fragmentation in the brain. It is able to cross into the brain to protect brain cells from free radical damage.

Support For People With Parkinsons Disease

Ask the expert: cure for Parkinsons disease

Early access to a multidisciplinary support team is important. These teams may include doctors, physiotherapists, occupational therapists, speech therapists, dietitians, social workers and specialist nurses.;Members of the team assess the person with Parkinsons disease and identify potential difficulties and possible solutions.There are a limited number of multidisciplinary teams in Victoria that specialise in Parkinsons disease management. But generalist teams are becoming more aware of how to help people with Parkinsons disease.;;

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Clinical Trials Often Fail

Did you know up to 10% of people taking part in clinical trials into early Parkinsons may not actually have the condition. And because they wont benefit from the treatment they are likely affecting results even leading to the failure of these trials.

Fortunately, through initiatives like the Critical Path for Parkinsons, were leading the way towards better clinical trials that are more likely to succeed.

Today, we are starting to identify what may be behind the loss of brain cells, and clinical trials are underway to try and tackle everything from the build up of alpha-synuclein to inflammation. But, without effective clinical trials, we risk failure simply because we are not testing treatments in the right way.

What Are The Symptoms Of Parkinson’s Disease

The main symptoms of Parkinson’s disease are:

  • tremor or shaking, often when resting or tired. It usually begins in one arm or hand
  • muscle rigidity or stiffness, which can limit movement and may be painful
  • slowing of movement, which may lead to periods of freezing and small shuffling steps
  • stooped posture and balance problems

The symptoms of Parkinson’s disease vary from person to person as well as over time. Some people also experience:

  • loss of unconscious movements, such as blinking and smiling
  • difficulties with handwriting
  • drop in blood pressure leading to dizziness
  • difficulty swallowing
  • sweating

Many of the symptoms of Parkinson’s disease could be caused by other conditions. For example, stooped posture could be caused by osteoporosis. But if you are worried by your symptoms, it is a good idea to see your doctor.

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What Is The Treatment For Parkinson’s Disease

    There is currently no treatment to cure Parkinson’s disease. Several therapies are available to delay the onset of motor symptoms and to ameliorate motor symptoms. All of these therapies are designed to increase the amount of dopamine in the brain either by replacing dopamine, mimicking dopamine, or prolonging the effect of dopamine by inhibiting its breakdown. Studies have shown that early therapy in the non-motor stage can delay the onset of motor symptoms, thereby extending quality of life.

    The most effective therapy for Parkinson’s disease is levodopa , which is converted to dopamine in the brain. However, because long-term treatment with levodopa can lead to unpleasant side effects , its use is often delayed until motor impairment is more severe. Levodopa is frequently prescribed together with carbidopa , which prevents levodopa from being broken down before it reaches the brain. Co-treatment with carbidopa allows for a lower levodopa dose, thereby reducing side effects.

    In earlier stages of Parkinson’s disease, substances that mimic the action of dopamine , and substances that reduce the breakdown of dopamine inhibitors) can be very efficacious in relieving motor symptoms. Unpleasant side effects of these preparations are quite common, including swelling caused by fluid accumulation in body tissues, drowsiness, constipation, dizziness, hallucinations, and nausea.

    Tips For Caring For Someone With Parkinsons Disease

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    Caring for a loved one with early onset Parkinsons can be difficult. If youre a caregiver for someone with this condition, its important that you remember your own emotional and physical health.

    Not only are you dealing with a difficult diagnosis, youre also managing an increased number of responsibilities. Burnout is common in caregivers, so make sure youre checking in with your own needs.

    The Michael J. Fox Foundation Center for Parkinsons Research recommends these tips for caregivers:

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    Symptoms Of Parkinsons Disease

    The type, number, severity and progression of Parkinsons disease symptoms vary greatly. Every person is affected differently they may not get every symptom.;

    Some of the more common symptoms are:

    • resting tremor
    • rigidity
    • blood pressure fluctuation;
    • constipation.;

    People living with Parkinsons for some time may experience hallucinations , paranoia ; and; delusions . These symptoms are able to be treated so have a talk with your doctor.

    What Did It Find

    • According to the UPDRS score, there was no difference in the progress of disease between the early-start group and the delayed-start group , .
    • The estimated rate of change in progression of the disease, a secondary outcome, was similar in both groups between 4 and 44 weeks .
    • Due to needing symptomatic relief, 87 people in the delayed-start group had levodopa before week 40.
    • The estimated rate of change in progression was faster between weeks 44 and 80 in the early-start group . This means starting levodopa earlier did not slow disease progression.
    • At 80 weeks, a similar proportion of participants were suffering complications, such as involuntary movements, from levodopa treatment .

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    The Symptoms Of Parkinsons Disease

    Some symptoms of PD are difficult to detect even by the specialists, while others are obvious to even untrained eyes. Parkinsons symptoms are different for every patient. Like any other chronic diseases, the degree that the disease worsen;differs in;every individual depending on their genes, diet, lifestyle and their exposure to environmental toxins.

    Some of the common symptoms of Parkinsons:

    • Constipation
    • Trouble;sleeping
    • Low blood pressure, feeling dizzy or fainting

    As a result of this disease that;is a deterioration of brain health and the central nervous system, if left untreated, some sufferers may also experience other brain issues such as Alzheimers Disease, dementia, severe depression and anxieties that may result in suicidal thoughts.

    Catch Parkinson’s Early For Better Support

    What is the best treatment for Parkinson

    Comanaging patients with Parkinson’s disease involves a back-and-forth relationship between the primary care physician and the neurologist over the course of a slow but progressive disease.

    Parkinson’s disease can be challenging to identify in its early stages, but catching emerging signs allows earlier intervention with medication and other support.

    There’s no clinically validated biomarker, so a diagnosis relies upon physicians identifying symptoms that might be subtle and difficult, particularly initially, to sort out from other conditions. One meta-analysis published 2016 in Neurology, which incorporated 11 studies that used pathology for comparison, found that physicians’ ability to diagnose idiopathic Parkinson’s disease was 80.6% overall. That accuracy rate hasn’t changed significantly over 25 years, the researchers wrote.

    Nearly 1 million Americans live with Parkinson’s, a number that’s projected to reach 1.2 million by 2030, according to a prevalence analysis by the Parkinson’s Foundation.

    While primary care physicians can manage a lot of the ongoing care, including prescribing, they might periodically need to refer the patient back to a neurologist, for issues ranging from reassessing the diagnosis to adjusting medication, Dr. Homayoun said.It’s kind of a back-and-forth relationship over the course of a slow but progressive disease.

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    At That Point I Had A Running List Of Symptoms That Got Longer Each Day

    My face felt stiff and I slurred my words and blanked out in the middle of sentences. I felt off-balance, rigid, and slow-moving. Sometimes I froze between steps. I could feel my body trembling inside and out. I was extremely fatigued, but I struggled to fall and stay asleep at night. I lost my sense of taste and smell. According to a cardiologist, I also had orthostatic hypotension, a form of low blood pressure that makes you feel dizzy when you stand up and can sometimes indicate deeper health issues.

    Id always been such a happy person, but people around me were starting to notice something was wrong. My employer at the time even told me Id lost my sparkle and had slowed down too much at school. Hearing this broke my heart.

    After doing my own research, I feared I may have Parkinsons disease , a progressive neurodegenerative disorder that affects dopamine-producing neurons in a part of the brain that affects multiple functions, including movement and cognition. I couldnt fathom how this could be possible when so few young women were diagnosed with Parkinsons, but I needed to know why I had so little energy I could no longer go on field trips with my youngest son.

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    After Struggling For Four Years I Was Finally Given A Diagnosis At The Age Of 44

    In July 2017, I found myself in yet another doctors office to see a third neurologist, this time for migraines. But the doctor didnt ask me about my headaches. Instead, he asked me to stand up and do a few exercises. Then, he sat down across from me, took a deep breath, and told me he suspected I had young onset Parkinsons disease .

    I had been fighting for so long to figure out what was wrong with me that I had a small sense of satisfaction in receiving a diagnosis. But that satisfaction was fleeting and overwhelmed by an impending sense of fear. I knew there was no cure and I knew first-hand what the disease could look likemy father-in-law had Parkinsons disease. While I explained to my children that the disease affected everyone differently, they were worried I would end up like their Poppy, and I was too. I feared that this disease would take away my two greatest passions: my ability to take care of my kids and make art.

    Most people with Parkinsons develop symptoms when theyre 50 or older, but 2 to 10 percent of uslike mebegin to experience signs of the disease earlier. Because young onset Parkinsons disease is so rare, its much harder to diagnose and many of us go untreated or misdiagnosed with something else.

    What Is Parkinson’s Disease

    When will there be a cure for Parkinson’s?

    Parkinson’s disease is the second most common neurodegenerative disorder and the most common movement disorder. Characteristics of Parkinsons disease are progressive loss of muscle control, which leads to trembling of the limbs and head while at rest, stiffness, slowness, and impaired balance. As symptoms worsen, it may become difficult to walk, talk, and complete simple tasks.

    The progression of Parkinson’s disease and the degree of impairment vary from person to person. Many people with Parkinson’s disease live long productive lives, whereas others become disabled much more quickly. Complications of Parkinsons such as falling-related injuries or pneumonia. However, studies of patent populations with and without Parkinsons Disease suggest the life expectancy for people with the disease is about the same as the general population.

    Most people who develop Parkinson’s disease are 60 years of age or older. Since overall life expectancy is rising, the number of individuals with Parkinson’s disease will increase in the future. Adult-onset Parkinson’s disease is most common, but early-onset Parkinson’s disease , and juvenile-onset Parkinson’s disease can occur.

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      Mayo Clinic Q And A: Rate Of Progression Of Parkinsons Disease Hard To Predict

      DEAR MAYO CLINIC: My father is 64 and was diagnosed with Parkinsons last year. So far his symptoms are very mild, but Im wondering what the typical progression of the disease is like. I have read that deep brain stimulation is sometimes recommended. When is this type of treatment usually considered? Is it safe?

      ANSWER: The symptoms of Parkinsons disease, or PD, tend to begin very gradually and then become progressively more severe. The rate of progression is hard to predict and is different from one person to another. Treatment for PD includes a variety of options, such as exercise, medication and surgery. Deep brain stimulation is one surgical possibility for treating PD, but its usually only considered in advanced cases when other treatments dont effectively control symptoms.

      Parkinsons disease is a syndrome which typically has no known cause. The diagnosis is based on symptoms. Neurologists who specialize in movement disorders typically have the most experience with PD diagnosis and treatment. There are many symptoms of parkinsonism. The most common include excessive slowness and lack of movement, as well as shaking or tremor.

      As in your fathers situation, symptoms are often mild at the outset. How quickly they get worse varies substantially, perhaps because there may be multiple underlying causes of the disease. In most cases, symptoms change slowly, with substantive progression taking place over the space of many months or years.

      This Was One Of A Few Times I Felt Like I Was Losing My Mind

      Members of my own family had begun to question the validity of my symptoms, too. When you dont have the support of the people closest to you, of course you begin to question yourself. I fell into a depression.

      After I collapsed in the shower, I pushed through one more semester at school. At the end of the school year, my contract was not renewed. I couldnt help but wonder if this was because Id lost my sparkle. I struggled to fight the hopelessness that so much uncertainty can breed.

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      What Will A Cure For Parkinson’s Look Like

      Because Parkinson’s varies so much from person to person, there may not be a single ‘cure’.

      Instead we may need a range of different therapies to meet the needs of the individual and their specific form of the condition.

      This mix may include treatments, therapies and strategies that can:

      • slow or stop the progression of the condition
      • replace or repair lost or damaged brain cells
      • control and manage particular symptoms
      • diagnose Parkinson’s at the earliest possible stage.

      And this could involve medical treatments, such as drugs and surgical approaches, as well as lifestyle changes, for example to diet and exercise.

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