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Parkinson’s And Diabetes Medication

The Open Lines Presence Approach

Pharmacology – Parkinsons Disease, Levodopa meds nursing RN PN NCLEX

Our proprietary PRESENCE Approach combines cutting-edge research from diverse medical fields and applies it to the speech and voice therapy programs we provide. We believe treatment entails more than just cognitive-communication or physical therapies. Our specially trained therapists also understand and work with you on the mental and emotional aspects of managing communication. This approach guides you in a forward motion to help you in the way you would like with the confidence you need to participate more fully in your life.

Nationally certified in New York, New Jersey, California, and Florida, our team consists of professional researchers/writers for prestigious journals, trusted academicians, reputable lecturers, and clinical experts who practice in and continue to collaborate with New Yorks top academic medical centers and private schools, and who stay current with the latest research advancements.

Our professional team is detail-driven in its quest to design a highly personalized program customized and designed just for you. Like motivational coaches and psychological counselors, Open Lines speech-language pathologists provide in-depth counseling within the scope of communication disorders to ensure you develop the mindset and habits necessary to build a solid foundation for meeting and sustaining your long-term goals.

Dr Farley Is The Leading Expert In Finding Which 30 Root Functional Causes Are Primary For You

My laboratory has never had anything but an extremely professional and proficient relationship with Dr. Farley and his staff. I believe that in the future more patients will seek care that is based on root functional causes rather than just managing symptoms.

Anyone who uses Dr. Farley today is getting insight, care and a dependable trusting doctor that should be the standard in doctoring across the United States and abroad.

I hope that patients can open their minds to understanding these concepts and not dismiss them because their doctor doesnt know about them. This healABILITY approach is an old and new evidence scientific based approach that frankly most doctors have absolutely no training in. Dr. Farleys office is run like a fine hotel that provides excellent customer service. So not only will you get exceptional care, but youll also be treated with a kind, warm and dependable staff. This book can aid anyone in getting insight into Dr. Farleys method of functional physiological based approach that has the potential to really help almost any condition. There are 30 key hidden root functional causes. Dr. Farley will help find which one of these 30 root functional causes are most important to correct for you to get well. Each person is unique in their physiology and biochemistry. Dr. Farley is the leading expert in finding which 30 root functional causes are primary for you.

Dr. Naveed Ashfaq MD emphasizes how powerful Dr. Farleys methods are and the impact they have.

Speech Language & Voice Services For Adults

If you are struggling to communicate with ease and confidence, Open Lines personalized and solution-focused approach is here to help you. Our therapists help you determine what is happening. They teach you how to address difficulties to optimize your communication so you may participate more fully in your life in a way that is most meaningful to you.

People often have difficulties that were not fully addressed in childhood or have developed in adulthood and are difficult to manage. These include challenges with language organization and expression, voice, stuttering, muscle tension, vocal fatigue, or articulation/speech clarity. Learn more about our services for cognitive-communication, voice, fluency, and articulation as you review frequently asked questions that follow.

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Intensive Speech And Voice Therapy Programs

Following your assessment but prior to the initiation of an intensive program, we begin with an initial education and training treatment session to review evaluation findings and discuss results, impressions, and a plan of exercises and expectations. During this session, there are opportunities to practice the treatment exercises, prepare for the intensive program, and answer any questions you may have.

In this intensive program, we target physical aspects of speaking, such as reduced loudness and speech clarity. However, we also address ones susceptibility to distractions, impaired attention and memory recall, and delayed word retrieval. The impact anxiety and stress can have on thinking and talking is also addressed.

Benefits of this program include:

  • Improved vocal loudness with no strain for a voice thatcan be heard and understood
  • Improved breath support and control
  • Improved intonation for voice that is more expressive
  • Improved speech clarity and intelligibility
  • More effective and easier communication in real-world settings
  • Improved quality of life

Treatment For Voice Disorders

Levodopa (L

Treatment for voice disorders is individualized and takes several factors into account, such as age, severity, and etiology, or the underlying cause of the voice disorder. Vocal needs in different settings are also considered. Techniques may include, but are not limited to the following:

  • Vocal Hygiene: Education about good vocal hygiene, including proper hydration and vocal use/misuse.
  • Resonant Voice Treatment: Treatment focusing on achieving a healthy vocal fold vibratory pattern and healthy voicing by establishing a forward vocal resonance and easy phonation. Treatment follows a hierarchy from basic sound production through conversational speech.
  • Exercises to improve breath support and control .
  • Vocal function exercises, stretches, manual techniques , and back pressure exercises to balance pressure above and below the level of the vocal folds, decrease extraneous muscle tension, improve voice quality and decrease vocal effort/fatigue.

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Common Diabetes Drugs May Help Prevent Parkinsons

27 October 2020

Elevated risk of Parkinsons disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers.

The researchers are testing one of the drugs, called exenatide, as a potential Parkinsons treatment in an upcoming clinical trial, and the new findings, published in Brain, lend support to repurposing diabetes medications for people with Parkinsons.

The research team, funded by The Cure Parkinsons Trust, examined patient records from 100,288 people with type 2 diabetes, from The Health Improvement Network database.

The findings confirmed that people with type 2 diabetes face an elevated risk of Parkinsons, when compared to another cohort of people without diabetes, but commonly prescribed drugs, GLP-1 agonists and DPP4 inhibitors, appeared to reverse that relationship.

The researchers found that people who were taking two particular classes of diabetes treatments GLP-1 agonists and DPP4 inhibitors were less likely to be diagnosed with Parkinsons disease a few years later , compared to people who were taking other diabetes medications. Those taking GLP-1 agonists were 60% less likely to develop Parkinsons compared to people taking other diabetes drugs.

Intensive Speech Programs For Parkinsons Disease And Other Neurological Disorders

People with speech and voice difficulties due to age-related voice and speech changes as well as acquired and progressive neurological conditions, such as Parkinsons disease, Multiple Sclerosis, Stroke, Cerebral Palsy, Downs Syndrome, and Autism.

A comprehensive evaluation of speech and voice.

Exercises to improve the strength of voice and clarity of voice and speech.

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Researchers Have Found That Parkinsons Medication May Be The Key To Preventing Teenagers With Type 1 Diabetes From Developing Heart Disease

Worsening diet and lifestyle choices have made chronic conditions like diabetes common among the young. One of those conditions is type 1 diabetes. Caused by the inability of the pancreas to produce insulin, type 1 diabetes patients require injections of insulin every day to merely stay alive. Otherwise, their sugar levels spike to levels that their body cannot take. However, researchers have found that Parkinsons medication may be the key to preventing teenagers with type 1 diabetes from developing heart disease.

According to Diabetes.co.uk, patients suffering from type 1 diabetes are at a higher risk of developing heart disease and those diagnosed with the condition as children are at an even greater risk than adults.

A study published in the American Heart Association Journals Hypertension section has revealed that teenagers who are given bromocriptine, used for the treatment of Parkinsons disease and type 2 diabetes, had lower blood pressure and less stiff arteries after a month.

The research involved the observation of 34 participants in the age group of 12 to 21, all of them diagnosed with type 1 diabetes for at least a year and whose HbA1c was 12% or less. They were randomly divided into two equal groups, out of which one received the bromocriptine quick-release therapy and the other received a placebo for one day.

The therapy also reduced aortic stiffness in the patients.

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New Study Suggests Bromocriptine Holds Promise For Preventing Heart Disease In Youth With Type 1 Diabetes

Parkinson’s Disease:- Prof Tom Foltynie “Does the repurposing of diabetes drugs offer hope for PD”
Date:
American Heart Association
Summary:
Teens with Type 1 diabetes who took bromocriptine, a medication usually prescribed to treat Parkinson’s disease, had lower blood pressure after one month of treatment compared to those who did not take the medicine. Participants taking the medication for one month also experienced significant improvements in aortic stiffness, a measure of vascular health. Larger, longer-term studies are needed to determine if bromocriptine may be recommended to adolescents with Type 1 diabetes.

Teens with Type 1 diabetes who took bromocriptine, a medication used to treat Parkinson’s disease and Type 2 diabetes, had lower blood pressure and less stiff arteries after one month of treatment compared to those who did not take the medicine, according to a small study published today in Hypertension, an American Heart Association journal.

High blood pressure and stiff arteries contribute to the development of heart disease. People with T1D, a lifelong, chronic condition in which the pancreas doesn’t produce enough insulin to control blood sugar levels, have a higher risk of developing heart disease than those without the condition. Those diagnosed with T1D as children have even higher risks for heart disease than people diagnosed in adulthood. Therefore, researchers are interested in ways to slow down the onset of vascular disease in children with T1D.

The study found:

The National Institutes of Health funded the study.

Story Source:

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Speech Therapy For Neurological Disorders

The Little LOUDers program is administered by our uniquely and expertly trained licensed speech-language pathologists with specialized certification in LSVT LOUD for Kids. This program targets many aspects of communication for children with wide a variety of conditions that make it challenging to speak.

A motor speech disorder reflects challenges with the physical aspect of speaking. LSVT LOUD for Kids utilizes an evidence-based, intensive protocol that targets normal, healthy vocal loudness and quality to achieve improvements in a wide variety of areas, including speech clarity and breath support. Open Lines SLPs also address other aspects of communication within the program. The impact anxiety can have on talking is also examined and addressed to help the child begin to improve the overall effectiveness of speech delivery so they can develop a sense of ease and confidence when communicating to better participate in social situations.

Understanding The Science Behind Neurobiomedicine And Our Approach To Helping You Restore Proper Function To Ultimately Help You Feel Better Look Better And Recover Your Health

Dr. Farleys Neurobiomedicine Health System can easily be understood when applied to the science of Translational Medicine, Psychosomatic Medicine and Somatopsychic Medicine as described from the National Institutes of Health. Please to learn more about Translational Medicine, Psychosomatic Medicine, Somatopsychic Medicine. Allopathic Medicine and even Integrative Medicine asks, Whats the diagnosis. Neuro-Biomedicine asks, Why you are personally having this happen?, and, What are your specific multifactorial causes?

Most doctors offices rely on outdated protocols that are 17-20 years behind the basic scientific research. The reason for this is lack of initiative by most doctors, and for medical legal reasons, they will not deviate from typical protocols even when they are outdated and produce terrible results for patients. The focus is not on the individual patient and their unique requirements, instead, the patient is literally pushed from office to office with the goal to just move the responsibility to another doctor or office . We do not treat any disease, instead we focus on your functional neuro-metabolic deficits. We will fight for you and your health! We will provide new possibilities and potential for greater healABILITY, greater depth of understanding, more compassionate listening, and ultimately, superior results aimed at restoring proper function. This, in turn, can have profound and positive improvements for the patients that qualify.

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Search Results And Details Of Included Studies

The flow chart of the study is presented in Figure 1. We found 894 unique articles after the systematic literature search. Of these, we selected 22 for full-text analysis. Twelve articles were excluded because 10 compared the PD risk between patients with and without DM and did not focus on specific DM medications and 2 had overlapping data with another one . Finally, 10 studies met the inclusion criteria and were analyzed for this review . Table 1 presents characteristics of all included studies. All of them were retrospective cohort studies with data extracted from insurance databases or national registries. The sample size varied widely from 5,530 to 1,308,089 patients. The included studies assessed the PD risk among patients with DM using sulfonylureas, metformin, GTZ, DPP4i, GLP1a, meglitinides, or α-glucosidase inhibitors. The studies also varied widely in the factors adjusted for the outcome analysis and the follow-up durations. The Newcastle-Ottawa score ranged between 6 and 8 for the included studies .

Figure 1. Study flow chart.

Table 1. Details of included studies.

Table 2. Risk of bias evaluation of individual studies.

Diabetes Drug May Reduce Risk Of Parkinsons

Procyclidine Hydrochloride Tablets, Treatment: Parkinson

A type of drug used to treat diabetes may have a protective effect against developing Parkinsons disease, according to a new study.

Results showed a 28% reduction in the incidence of Parkinsons disease among patients with diabetes taking glitazonesrosiglitazone or pioglitazonecompared with those taking other anti-diabetes treatments who had never taken glitazones._________________________________________________________________________________________________________________________________________________________________

Can Bright Light Improve Sleep in Parkinson’s?_________________________________________________________________________________________________________________________________________________________________

We often hear about negative side effects associated with medications, but sometimes there can also be unintended beneficial effects, says lead study author Ruth Brauer, PhD, of Kings College London, who worked on the study while she was at the London School of Hygiene & Tropical Medicine.

Previous research has demonstrated the potential of glitazones to reduce Parkinsons risk in rodent models and in vitro, but the authors believe this study is the first to show the same effect in humans. Our results suggest that treatments which activate the PPAR receptor in the same way as glitazones could be promising targets in future drug research, Brauer says.

Colleen Mullarkey

Reference

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A Neurobiomedicine Functional Restoration Prescription Treatment Program

healABILITY: Preservation of health and wellness through the promotion of well-being prevention of disease, and promotion and support of the inherent or innate recuperative abilities of the body.

Dr. James F. Farley, DC, BA, BS, MS, BCIM, FAAIM, FAIS

Dr. James F. Farley, DC, BA, BS, MS, BCIM, FAAIM, FAIS

Dr. James F. Farley, DC, BA, BS, MS, BCIM, FAAIM, FAIS

Allostatic Stress, Neurobiomedicine Health System creates healability

Data Extraction And Risk Of Bias Assessment

We prepared a data extraction form to compile relevant details from the studies. The final version of this template was approved by all the study investigators it included details of the first author, publication year, study type, location, the database used, study period, sample size, the mean age of the sample, DM medication studied, medication users, factors adjusted for the outcome, outcome data, and follow-ups. Data were extracted independently by two reviewers, and any disagreements were resolved by discussion.

The methodological quality of the studies included was assessed using the Newcastle-Ottawa scale . This too was carried out in duplicate and independently by two study investigators. Studies were awarded points for selection of study population, comparability, and outcomes. The maximum possible score was nine. We also assessed the certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation tool using the GRADEpro GDT software .

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Researchers Think These Factors May Be Linked To Parkinsons

These results are an encouraging and critical step in our pursuit of therapies that slow or stop Parkinsons progression, Patrik Brundin, MD, PhD, a professor of neuroscience and the director of the Parkinsons Disease Center at Van Andel Institute in Michigan, said in a press release

Both the Van Andel Institute and the U.K.s Cure Parkinsons funded the trial.

We believe diabetes medications, such as liraglutide, hold particular promise and look forward to additional results from the trial, added Brundin, who is also chair of Cure Parkinsons International Linked Clinical Trials program, which aims to repurpose approved medications to treat Parkinsons and supported the liraglutide study.

Additional trial results are expected later this year and in 2023.

Increasing evidence suggests that GLP-1R agonists, which can reduce appetite and help to control sugar levels in the body by promoting insulin production, may be potential therapies for Parkinsons.

Previous studies showed that GLP-1R agonists have neuroprotective effects resulting in motor and non-motor improvements in animal models of Parkinsons and suggest that people taking such medications are at a lower risk of developing Parkinsons.

In addition, data from a previous Phase 2 clinical trial showed that exenatide, a short-acting GLP-1R agonist sold as Byetta, was superior to a placebo at aiding motor function in Parkinsons patients on standard therapy.

Dr Farleys Neurobiomedicine Health System Can Easily Be Understood When Applied To The Science Of Translational Medicine As Described From The National Institutes Of Health

Bromocriptine for both Pakinson disease and Diabetes Mellitus

Please to learn more about Translational Medicine. Most doctors offices rely on outdated protocols that are 17-20 years behind the basic scientific research. The reason for this is lack of initiative by most doctors, and for medical legal reasons, they will not deviate from typical protocols even when they are outdated and produce terrible results for patients. The focus is not on the individual patient and their unique requirements, instead, the patient is literally pushed from office to office with the goal to just move the responsibility to another doctor or office . We do not treat any disease, instead we focus on your functional neuro-metabolic deficits. We will fight for you and your health! We will provide new possibilities and potential for greater healABILITY, greater depth of understanding, more compassionate listening, and ultimately, superior results aimed at restoring proper function. This, in turn, can have profound and positive improvements for the patients that qualify.

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