Symptoms That May Be Related To Pd But That Few People Know About
People with PD and care partners may suspect that a particular symptom is related to PD, but they cant find information about it, so they are not sure. Two symptoms that pop up in this category are runny nose and breathing problems, which well focus on today. Of course, if these are new symptoms for you, they could be indicative of a new problem, including infection with COVID-19, so make sure to get yourself checked out by your doctor. However, if all else is ruled out, PD could be to blame. Excessive sweating and specific skin disorders are in this category as well and have been addressed previously.
Runny Nose And Parkinsons Disease
Runny nose, or rhinorrhea in medical jargon, is an annoying symptom that has been shown in a number of studies to be more common among people with PD than those without PD. The rhinorrhea of PD is not associated with a viral infection or environmental allergies, or any other common cause of runny nose.
Rhinorrhea can be an early feature of PD, sometimes present at the time of diagnosis. In fact, studies have shown that rhinorrhea is not correlated with disease duration, disease severity, or whether the PD is characterized more by tremor or gait difficulties. One study tested the smell of those with runny nose versus those without and determined that the presence of rhinorrhea did not correlate with deficits in the sense of smell.
There are no studies in the medical literature addressing how to treat the runny nose associated with PD. Ipratropium bromide is an anti-cholinergic medication that does not cross the blood-brain barrier and is available in two forms an inhaled form to treat asthma, chronic bronchitis and emphysema; and a nasal spray that is used to treat allergic and non-allergic runny nose. The nasal spray may be worth a try in PD-related rhinorrhea.
Rhinorrhea Frequency In Pd And Nc
Rhinorrhea of any cause occurred more frequently in PD compared with NC . Non-rhinitic rhinorrhea was five times more prevalent in PD than NC . Mean UPSIT scores and VMAT2 BPND activity throughout the striatum were significantly lower in the PD group . There was no difference in age or rhinorrhea medications between the patients and controls, but NC had a slightly higher MMSE score .
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What Are The Common Symptoms Of Lewy Body Dementia
This condition impairs thinking, such as memory, executive function , or the ability to understand visual information. People with LBD may have fluctuations in attention or alertness; problems with movement including tremors, stiffness, slowness and difficulty walking; hallucinations; and alterations in sleep and behaviour.;
Changes In Sleeping Patterns
As Parkinsons progresses, you can also develop problems with sleep patterns. These may not happen in the early stages, but can be noticeable later. You might wake up often in the middle of the night or sleep more during the day than you do at night.
Another common sleep disturbance for people with Parkinsons is rapid eye movement sleep behavior disorder. This is when you start acting out your dreams in your sleep, such as verbally and physically, which can get uncomfortable if someone is sharing your bed. Dr. Rundle-Gonzalez says many times a bed partner will be the one to notice sleep problems.
REM sleep behavior disorder can also happen in people who dont have Parkinsons. However, if this isnt something youve dealt with before, its likely related to your disease. There are medications your doctor can prescribe to help you sleep comfortably through the night.
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Symptoms That May Be Related To Pd
These symptoms can be associated with PD, but are also commonly associated with other medical;conditions, so more testing is necessary. For example, weight loss may be associated with PD, but may also be a sign of a gastrointestinal problem or cancer. Pain may be associated with PD, but could be also due to arthritis, spinal stenosis, cancer, or a whole host of other causes.
There is a fourth category of non-motor symptoms that I would like to focus on now:
Common Treatments For Lewy Body Dementia
Overview Lewy body dementia is a condition in humans. When there is a progressive reduction in mental abilities, it causes visual hallucinations, altered alertness, and attention, Parkinsons disease . It is the second most popular advanced dementia; Alzheimers disease is the first. Deposition of proteins in cells …
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Depression And Parkinson’s Disease
Depressive symptoms occur in up to half of PD patients, and major depression in 10-20%. However, some patients appear to be depressed because they have difficulty with initiating behaviors . Patients should be routinely screened for depression, but the aforementioned behavior should be distinguished from true depression. Although there is no clear consensus about the best treatment, sertraline may be beneficial and less apt to aggravate motor symptoms than other SSRIs. Ropinirole and pramipexole have also been shown to improve depressive symptoms. They may be used instead of or in combination with levodopa, though treatment of depression is an off-label use. These drugs are also effective for treating restless leg syndromes in patients with PD.
|Table 2. Treatment Options for Non-Motor Symptoms of Parkinson’s Disease|
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However, a runny nose can also be a symptom of a wide variety of mild to serious disorders, even depression.
A cold or sinusitis are typical causes of a drippy nose, as is irritation. And some people’s noses are more susceptible to irritants.
A caregiver can observe if someone’s runny nose is caused by environmental irritants, such as pollution, dust, tobacco smoke, perfume, scented candles or oils. Central heating can exacerbate the condition. If not an environmental factor, a runny nose could be caused by allergies to pets, a new detergent or fabric softener, a new soap or shampoo, or foods.
Geriatric rhinitis is a familiar and bothersome condition in aging adults and can cause headaches and diminished concentration, which can often be magnified in individuals with dementia-related illnesses.
Some individuals have chronic nose drips that have no underlying cause. This condition is called nonallergic rhinitis. Individuals typically sneeze a lot and experience nasal congestion, symptoms much like hay fever. However, the individual is not allergic to anything. Though little can be done about this condition, the caregiver can identify triggers that could possibly make the nasal drip worse, such as certain odors, medications, changes in diet or food, and the weather.
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Cognition In Parkinson’s Disease
Cognitive impairment is common in PD; 40-80% of patients eventually develop dementia. The risk increases with duration of illness and older age. In contrast to Alzheimer’s disease, patients with PD dementia most commonly have deficits in attention, processing speed, executive ;functions, and visual-spatial function while language skills are preserved. And, while patients may have difficulty with information retrieval, severe memory loss does not occur. Clinicians should monitor for cognitive decline and facilitate financial planning and early completion of advanced directives. Cholinesterase inhibitors such as donepezil and rivastigmine are effective in PD dementia, resulting in moderate improvements in cognition and hallucinations.
Stooping Or Hunching Over
Are you not standing up as straight as you used to? If you or your family or friends notice that you seem to be stooping, leaning or slouching when you stand, it could be a sign of Parkinson’s disease .
What is normal?If you have pain from an injury or if you are sick, it might cause you to stand crookedly. Also, a problem with your bones can make you hunch over.
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A good rule of thumb to treat a runny nose is to always keep the individual’s nasal passages moist. You should consult a physician before using any type of nasal spray or medication. A room humidifier for the individual with the chronic runny nose is also suggested.
Questions about Alzheimer’s disease or a related disorder can be sent to Dana Territo, the Memory Whisperer, director of services at Alzheimer’s Services of the Capital Area at or visit the organization at 3772 North Blvd., Baton Rouge.
What Lifestyle Changes Can I Make To Ease Parkinsons Symptoms
Exercise: Exercise helps improve muscle strength, balance, coordination, flexibility, and tremor. It is also strongly believed to improve memory, thinking and reduce the risk of falls and decrease anxiety and depression. One study in persons with Parkinsons disease showed that 2.5 hours of exercise per week resulted in improved ability to move and a slower decline in quality of life compared to those who didnt exercise or didnt start until later in the course of their disease. Some exercises to consider include strengthening or resistance training, stretching exercises or aerobics . All types of exercise are helpful.
Eat a healthy, balanced diet: This is not only good for your general health but can ease some of the non-movement related symptoms of Parkinsons, such as constipation. Eating foods high in fiber in particular can relieve constipation. The Mediterranean diet is one example of a healthy diet.
Preventing falls and maintaining balance: Falls are a frequent complication of Parkinson’s. While you can do many things to reduce your risk of falling, the two most important are: 1) to work with your doctor to ensure that your treatments whether medicines or deep brain stimulation are optimal; and 2) to consult with a physical therapist who can assess your walking and balance. The physical therapist is the expert when it comes to recommending assistive devices or exercise to improve safety and preventing falls.
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Can Parkinsons Disease Be Prevented
Unfortunately, no. Parkinsons disease is long-term disease that worsens over time. Although there is no way to prevent or cure the disease , medications may significantly relieve your symptoms. In some patients especially those with later-stage disease, surgery to improve symptoms may be an option.
Medication Not Working The Way It Used To
In the early stages, taking medicine works well to get rid of symptoms. But as Parkinsons progresses, your medication works for shorter periods of time, and symptoms return more easily. Your doctor will need to change your prescription.
Dr. Valerie Rundle-Gonzalez, a Texas-based neurologist, says to pay attention to how long your medicine takes to kick in and when it stops working. She says you should feel like symptoms significantly improve or are almost gone while on medication.
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Common Cold And Parkinson’s
In a way, yes. You get a little headache and a tickle in your nose and all hell breaks out. It’s as if there is a new kid on the block and all the other kids are being jostled out of their happy routine. Your symptoms rebel and fight to regain your attention. Your muscle and joint pains start earlier and by two thirty in the morning, you just have to get up and move your body. It feels like you are carrying a watermelon around in your gut. Your calves spasm and the dreaded curly toes seem to be mocking you, there is nothing you can do to stop them from playing their macabre tune at the end of your feet. Day one and you feel defeated. But wait, now youre sneezing and coughing – it is just a cold that’s causing this chaos. You can overcome.
Years ago, when I was working on a brand of cold medication, we conducted some very insightful research into the psychology of the cold. In the first stage of a cold there is relief, we deserve a rest a little pampering goes a long way. So Parkie peeps, rest a while. After a day or two, the study told us, the cold starts to be a nuisance. People can’t do the things they want to do, they feel helpless, hopeless, frustrated and out of control. Now they start to look for ways to feel better. The search can be almost frantic.
Is A Chronic Runny Nose Common With Alzheimer’s Disease Here’s What To Know
The restrictions of the coronavirus pandemic can rob Alzheimer’s patients and their caregivers of the support they need.
Older adults with Alzheimer’s disease oftentimes show symptoms of a condition called geriatric rhinitis, which is an inflammation or irritation of the mucous membrane inside the nose. This inflammation caused by viruses, bacteria, irritants or allergens produces large amounts of mucous, resulting in a runny nose or postnasal drip.
As we age, the nasal membrane atrophies, and there is a recession of the collagen fibers and loss of elastic fibers in the skin. The weakening or thinning of these connective tissues in the nose can cause the tip of the nose to droop which restricts airflow and can cause nasal obstructions. Some of the symptoms of geriatric rhinitis in addition to a runny nose include loss of smell, crustiness in the nostrils and a dry cough.
A runny nose is very common in individuals with Lewy body dementia and Parkinson’s disease, and common in the later stages of Alzheimer’s disease. Some medications can lead to this condition.
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Increased Feelings Of Anxiety Or Depression
Anxiety and depression have been linked to Parkinsons. In addition to movement problems, the disease can also have an impact on your mental health. Its possible that changes in your emotional well-being can be a sign of changing physical health as well.
If you are more anxious than usual, have lost interest in things, or feel a sense of hopelessness, talk to your doctor.
Using A Runny Nose As A Pre
This raised another question. There has been a lot of interest in the last several years in finding pre-motor symptoms of PD. That is, identifying people with Parkinsons Disease even before they have their first symptom of tremor, slowness, stiffness or anything else like that. If we finally find a medicine that will slow the progression, then if we can identify people who have Parkinsons Disease before they have movement problems, maybe we will prevent them, or at least forestall them.
In our studies weve had conflicting results about the connection between smell and runny nose, so we dont know whether runny nose interferes with smell or not.
We are hoping to extend our study to see if the problem of rhinorrhea affects all of Parkinsons Disease patients in the US or whether it is only a Rhode Island problem, possibly due to something in the air. As Yogi Berra said, You can see a lot just by looking. Keep tuned.
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Symptoms That Are Commonly Associated With Pd
These symptoms include sleep disorders, abnormalities in blood pressure, urinary problems, constipation, depression, and anxiety. Even though these symptoms are so commonly seen in PD, they are also commonly associated with other issues that have nothing to do with PD, so it is vital to keep an open mind about their cause. If any symptom is new or worsening, it could be an indication of a new medical problem. For example, urinary problems are extremely common in PD, but may be a sign of an enlarged prostate, which can be treated in an entirely different way.
Anticholinergic Nasal Spray Eases Rhinorrhea In Parkinson’s
STOCKHOLM, Sweden Rhinorrhea in patients with Parkinson’s disease may respond to anticholinergic nasal spray, hints a small pilot study.
“All of our patients responded very well without any significant side effects,” Rachana Gandhi, MD, from the Department of Neurology, Cleveland Clinic Florida in Weston, Florida, told Medscape Medical News.
Rhinorrhea is a common nonmotor symptom of PD, with a reported prevalence between 24% and 50%. Yet, “it’s not well recognized or studied,” Dr. Gandhi said.
“A persistent runny nose is not only bothersome, but can also lead to postnasal drip and coughing. Eating may make it worse, so many patients avoid social meal and gatherings,” she explained. “Many of our patients as well as family members found it emotionally disturbing.”
While many medications are available for rhinorrhea, “none of them is actually well studied, which prompted us to do a pilot study to assess efficacy of anticholinergic spray in PD patients,” Dr. Gandhi said.
She presented the study at the recent International Parkinson and Movement Disorder Society 18th International Congress of Parkinson’s Disease and Movement Disorders.
Symptom Relief, Improved Quality of Life
The study included 5 patients who were at least 60 years of age and who had rhinorrhea and a diagnosis of PD for less than 7 years. Two of the 5 patients developed rhinorrhea within the first year of being diagnosed with PD.
Table. Change in SNOT-22 Score After Treatment
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The Overlaps Between Allergic Reactions And Parkinson’s Disease
Indeed, a perpetually blocked or “stuffy” nose is common with Parkinson’s too. Again, this was true for me and looking back, it was the case long before I was diagnosed: I had become a persistent mouth breather, and had stopped being able to breathe through my nose without a great deal of effort, many years before my PD diagnosis!
The Holistic Wellness expert, Deb Helfrich, who helped me start the Out-Thinking Parkinson’s project, noticed my issues with breathing early on. She set me on the path to seek to unblock my nasal problems, and to try to revert to a natural nose breather. We tried Himalayan pink sea salt inhalers, and then progressed to a sea salt nasal spray, available on the market for allergy relief. We found it really helped. Later, I added in anti-snoring plugs which open up the nasal passages. I began to both spray my nose and insert the plugs each and every time I became symptomatic throughout the day. Cumulatively, as the weeks passed, this process worked for me. I now rarely have the slack jaw issue and automatically nose breathe, even at night.
UK: from LloydsPharmacy – this is the product I use.
USA: Bionette have a similar product.
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