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Friday, July 1, 2022
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How Do You Slow Down Parkinson’s

How Do I Prevent Falls From Common Hazards

How Do You Slow Time Down With Novelty? | Ft. William James and Parkinsons Law
  • Floors: Remove all loose wires, cords, and throw rugs. Minimize clutter. Make sure rugs are anchored and smooth. Keep furniture in its usual place.
  • Bathroom: Install grab bars and non-skid tape in the tub or shower. Use non-skid bath mats on the floor or install wall-to-wall carpeting.
  • Lighting: Make sure halls, stairways, and entrances are well-lit. Install a night light in your bathroom or hallway and staircase. Turn lights on if you get up in the middle of the night. Make sure lamps or light switches are within reach of the bed if you have to get up during the night.
  • Kitchen: Install non-skid rubber mats near the sink and stove. Clean spills immediately.
  • Stairs: Make sure treads, rails, and rugs are secure. Install a rail on both sides of the stairs. If stairs are a threat, it might be helpful to arrange most of your activities on the lower level to reduce the number of times you must climb the stairs.
  • Entrances and doorways: Install metal handles on the walls adjacent to the doorknobs of all doors to make it more secure as you travel through the doorway.

Why Exercise Can Help Delay The Onset Of Parkinsons Disease

Parkinsons disease affects more than a million people in the United States alone, and it is the second most common neurodegenerative disorder in the country. It is also the most common of movement disorders, which also include neurological disorders like Dystonia, Huntingtons disease, Tourettes syndrome, and others. In fact, there are 60,000 new patients diagnosed with PD each year, and men are one and a half times more likely to develop the disease than women.

PD affects both motor and non-motor related faculties and could include symptoms such as tremors, limb rigidity, gait and balance difficulties, slowness of movement, depression, constipation, sleep issues, and cognitive impairment. Though these symptoms may not be readily apparent, they develop and progress as the disease spreads.

Experts remain unsure exactly what causes Parkinsons a combination of environmental and genetic factors seems to be at play but the good news is that there are ways to slow its onset and protect against its development. One helpful method is to maintain good health through a balanced diet high in fiber and antioxidant-rich foods . Other preventative measures include getting proper sleep, minimizing stress, limiting exposure to toxins, and avoiding head injuries.

Research shows that something else is also promising in preventing and delaying the onset of PD: regular exercise.

Forget Fava Beans For Parkinsons

Fava beans contain an amino acid known as levodopa. Levodopa is an active ingredient in some Parkinsons medications. Seems like a good reason to eat a lot of fava beans, right?

Nope. Dr. Gostkowski explains that the amount in the beans is tiny compared to whats in your medication. You cant eat enough fava beans to have any effect on your symptoms, he says.

Bananas also have levodopa in them, Dr. Gostkowski says. But, like fava beans, its not possible to eat enough bananas to affect PD symptoms. Of course, if you like fava beans or bananas, enjoy! But dont go overboard or expect them to work like medication. Eat a variety of fruits, veggies, legumes and whole grains for balance.

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Theory Of Pd Progression: Braaks Hypothesis

The current theory is that the earliest signs of Parkinson’s are found in the enteric nervous system, the medulla and the olfactory bulb, which controls sense of smell. Under this theory, Parkinson’s only progresses to the substantia nigra and cortex over time.

This theory is increasingly borne out by evidence that non-motor symptoms, such as a loss of sense of smell , sleep disorders and constipation may precede the motor features of the disease by several years. For this reason, researchers are increasingly focused on these non-motor symptoms to detect PD as early as possible and to look for ways to stop its progression.

Page reviewed by Dr. Ryan Barmore, Movement Disorders Fellow at the University of Florida, a Parkinsons Foundation Center of Excellence.

*Please note that not all content is available in both languages. If you are interested in receiving Spanish communications, we recommend selecting both” to stay best informed on the Foundation’s work and the latest in PD news.

How Patients Are Using Cycling To Slow Down Parkinson’s

How to slow your Parkinson

Parkinsons symptoms include tremor, rigid muscles and problems with movement. While early treatment can delay the worst symptoms, people almost always get worse. About 60,000 Americans are diagnosed with Parkinson’s disease each year and about a million Americans have Parkinsons now.

No medical therapy can cure Parkinsons and while exercise was always shown to help people feel better, it was not generally accepted as a true therapy until recently.

Now teams are trying to find out how much exercise helps and just which symptoms it affects. Doctors say theyd be thrilled just to slow the inevitable worsening of the disease and if they can freeze progression or reverse symptoms, that would be a home run.

Corcos and colleagues say the most intense exercise appears to have at least temporarily frozen symptoms in many of their volunteers.

“The earlier in the disease you intervene, the more likely it is you can prevent the progression of the disease,” Corcos said in a statement.

“We delayed worsening of symptoms for six months, he added. Whether we can prevent progression any longer than six months will require further study.”

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They worked with 128 patients with early stage Parkinsons. They randomly assigned them to either moderate exercise four days a week, intense exercise four days a week, or no additional exercise.

“This is not mild stretching. This is high intensity, Corcos said.

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What Exactly Does Parkinsons Disease Entail

Parkinsons is a nervous system disorder. Its progressive, which means it gradually gets worse. At first many of the symptoms are minor and may only be on one hand. Over time, these symptoms affect the rest of the body. One of the most common symptoms that will noticeably get worse is the tremor.

Some of the symptoms will only be visible to others. While you think youre showing emotion, people wont see any movement in your face. You may find your arms dont swing while walking, which is often overlooked in the early stages. Its when the speech becomes slurred and other symptoms appear that people start taking the condition seriously.

While its a chronic disorder , there are treatments to help manage the symptoms. It is possible to live a somewhat normal life for many years with the disease.

Slowing The Spread Of Alpha Synuclein Pathology

There is a mantra that disease modifying treatments must be initiated early if they are to be of any use in preventing disease progression. This is because post mortem specimens suggest that>50% of SNc dopaminergic neurons are already lost by the time that patients present with the classical motor features of the disease . Given that there are many effective symptomatic treatments to help the motor, dopaminergic deficits in PD, it can be argued that the important unmet needs in PD relate to cognitive, speech, gait and balance difficulties and autonomic failure. In this case any treatment that prevented onset/worsening of these symptoms, would be highly relevant even in patients with established motor PD, and would be addressing the major challenges that patients face in its long-term management. From another perspective, since many of these non-motor features of PD may precede the onset of motor symptoms, we may have an even earlier window to start therapy, and have an opportunity to slow or stop the development of even the first motor symptoms of PD.

Beyond this, the companies will have to look carefully at the emerging data to decide whether a strategy of enrichment might be advantageous, and/or whether to risk extending trial eligibility to patients with more established disease than those currently being recruited.

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When To Seek Hospice Care

When you or your loved one have a life expectancy of six months or less, you become eligible for hospice care a type of comfort care provided at the end of life for someone living with end-stage Parkinsons disease. Hospice provides extra support so your loved one can live as comfortably as possible.

If you have experienced a significant decline in your ability to move, speak, or participate in activities of daily living without caregiver assistance, its time to speak with a hospice professional.

Read more: What is hospice care?

Some of the things that determine whether your loved one with end-stage Parkinsons is eligible for hospice include: difficulty breathing, bed bound, unintelligible speech, inability to eat or drink sufficiently, and/or complications including pneumonia or sepsis.

If you live in South Jersey, our nurse care coordinator can answer your questions and decide if your loved one is ready for hospice care. Call us 24/7 at 229-8183.

Nanotechnology: Science Fiction Or Fact

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The grand vision would be to develop a therapy that would accurately target alpha synuclein pathology, dissolve the toxic aggregates and push the equilibrium back towards normal monomeric alpha synuclein. Would this sci-fi dream ultimately be the definitive cure for PD? With the aptly named, graphene quantum dots , perhaps this dream is right in from of us. These nanoparticles have been shown to penetrate the blood brain barrier in rodents and protect dopaminergic neurons exposed to alpha synuclein preformed fibrils. In vitro data suggests these GQDs can in fact interact with alpha synuclein fibrils, blocking their formation and even promoting their disaggregation . If safe and sufficiently selective, might these GQDs be the magic bullet for PD?

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Managing Parkinsons Disease Yourself

If you notice any of the symptoms, the best thing you can do is talk to your doctor. While there may not be a cure, there are treatments to help manage symptoms and improve your abilities. You can still do some daily tasks.

The disease is progressive. This can take years or months. It really depends on how you protect your health and the help you seek both medically and mentally. Its time to take control of the disease and live your life as full as you wish.

Experts Explore Which Of The Existing Strategies To Slow Down Or Stop The Processes Of Parkinsons Disease Are Most Likely To Be Successful Over The Next 20 Years

Understanding of the processes involved in Parkinsons disease degeneration has vastly improved over the last 20 years. Published in the Journal of Parkinsons Disease, authors Tom Foltynie, MBBS, PhD, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology & The National Hospital for Neurology and Neurosurgery, UK, and J. William Langston, MD, Associate Director, Stanford Udall Center, Department of Pathology, Stanford University, USA, explain the progress of research.

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Discovery Could Help Slow Down Progression Of Parkinson’s Disease

Rutgers collaborates with Scripps Research hoping to develop new drug treatment

Rutgers University

A collaboration between scientists at Rutgers University and Scripps Research led to the discovery of a small molecule that may slow down or stop the progression of Parkinson’s disease.

Parkinson’s, which affects 1 million people in the United States and over 10 million worldwide according to the Parkinson’s Foundation, is a neurodegenerative disorder with no cure. Symptoms develop slowly over time and can be debilitating to patients, who most recognizably develop tremor, slow movements and a shuffling gait.

A key feature of Parkinson’s disease is a protein named -synuclein, which accumulates in an abnormal form in brain cells causing them to degenerate and die. However, it has been difficult to target -synuclein because it does not have a fixed structure and keeps changing its shape, making it very difficult for drugs to target. Because higher levels of the protein in the brain speed the degeneration of brain cells, scientists have been looking for ways to decrease the protein production as a form of treatment.

“We found the molecule to be very selective at both the RNA level and the protein level,” Disney says.

“The reach of our study could go beyond people with Parkinson’s disease to many other neurodegenerative diseases. It is a classic example of how interdisciplinary research leads to significant change,” she shares.

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What Causes Parkinson Disease

Small molecule may slow down Parkinson

Parkinson disease arises from decreased dopamine production in the brain. The absence of dopamine makes it hard for the brain to coordinate muscle movements. Low dopamine also contributes to mood and cognitive problems later in the course of the disease. Experts don’t know what triggers the development of Parkinson disease most of the time. Early onset Parkinson disease is often inherited and is the result of certain gene defects.

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How Do You Stop Stiffness In Parkinson’s

Our community shared the remedies that have helped them relieve rigidity.Move more during the day. Increasing everyday movement can help improve motor symptoms, which in turn helps prevent stiff muscles. … Exercise. … Try heat or a hot bath to relax muscles. … Try weight lifting. … Consider yoga.2

What Is Parkinson Disease

Parkinson;disease is a movement disorder. It can cause the muscles to tighten and become rigid This makes it hard to walk and do other daily activities. People with Parkinsons disease also have tremors and may develop cognitive problems, including memory loss and dementia.

Parkinson;disease is most common in people who are older than 50. The average age at which it occurs is 60. But some younger people may also get Parkinson disease. When it affects someone younger than age 50, it’s called early-onset Parkinson disease. You may be more likely to get early-onset Parkinson disease if someone in your family has it. The older you are, the greater your risk of developing Parkinson disease. It’s also much more common in men than in women.

Parkinson disease is a chronic and progressive disease.; It doesn’t go away and continues to get worse over time.

Read Also: Life Expectancy With Parkinson Disease

What Type Of Exercise Is Best

Any type of exercise is beneficial, so patients should focus on activities they enjoy. Patients who engage in movement and training exercises like yoga, jogging, swimming, cycling, or calisthenics improve their physical fitness and work towards alleviating PD symptoms. For example, yoga improves balance and flexibility, while running or cycling increases endurance.

More important than the type of exercise is the frequency that patients exercise. Patients with PD who engaged in exercise programs of any kind for longer than six months have shown improvement in balance and mobility far more than individuals who enrolled in short-term programs.

Studies indicate that short bursts of intense exercise may also be more effective than longer, less demanding sessions. A recent study published in the Journal of Rehabilitation Medicine outlined the impact of High-Intensity Interval Training cycling in patients with mild-to-moderate PD. Participants saw improvements in their cardiovascular health, brain functionality, and their bodys circulation of oxygen after periods of short, intense bursts of cycling for three times a week over an eight week period.

What Is Pill Rolling In Parkinson’s

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pillrollingParkinson’s

A pill rolling tremor is the most common tremor associated with Parkinson’s disease, a nervous system disorder that affects movement. It’s usually one of the earliest symptoms of Parkinson’s disease.

Secondly, what are the four cardinal signs of Parkinson’s disease? Cardinal symptoms. Four symptoms are considered cardinal in PD: bradykinesia, tremor, rigidity, and postural instability also referred to as parkinsonism. Tremor is the most apparent and well-known symptom.

Also asked, what does Pill rolling mean?

n. A circular movement or tremor of the tips of the thumb and the index finger when brought together, seen in Parkinson’s disease.

What are early warning signs of Parkinson’s disease?

  • cramped handwriting or other writing changes.
  • tremor, especially in finger, hand or foot.
  • uncontrollable movements during sleep.
  • limb stiffness or slow movement
  • voice changes.
  • rigid facial expression or masking.
  • stooped posture.

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What Are The Different Stages Of Parkinsons Disease

Each person with Parkinsons disease experiences symptoms in in their own unique way. Not everyone experiences all symptoms of Parkinsons disease. You may not experience symptoms in the same order as others. Some people may have mild symptoms; others may have intense symptoms. How quickly symptoms worsen also varies from individual to individual and is difficult to impossible to predict at the outset.

In general, the disease progresses from early stage to mid-stage to mid-late-stage to advanced stage. This is what typically occurs during each of these stages:

Early stage

Early symptoms of Parkinsons disease are usually mild and typically occur slowly and do not interfere with daily activities. Sometimes early symptoms are not easy to detect or you may think early symptoms are simply normal signs of aging. You may have fatigue or a general sense of uneasiness. You may feel a slight tremor or have difficulty standing.

Often, a family member or friend notices some of the subtle signs before you do. They may notice things like body stiffness or lack of normal movement slow or small handwriting, lack of expression in your face, or difficulty getting out of a chair.

Mid stage

Mid-late stage

Standing and walking are becoming more difficult and may require assistance with a walker. You may need full time help to continue to live at home.

Advanced stage

There Are Risk Factors Involved

While researchers dont understand everything, there are certain noted risk factors involved. Genetics are one. If you have a family member with Parkinsons, there is a chance that you can develop it. However, the risks are small except in cases where multiple family members have the disorder.

Men are more likely to develop it than women, but the reasons for this are unknown. Those who are older are also more likely to see symptoms, especially from around the age of 60 years. Of course, in the cases of like Michael J. Fox, there is a chance you can develop it at a younger age.

Those who are exposed to more pesticides and herbicides have seen an increase in the risk of development. However, the increased risk is minor.

Because the risk factors and causes are unknown, its currently impossible to prevent the disease entirely. Researchers are still looking for a way to do this.

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